Author : Susanna Pietropaolo
Publisher :
Page : 472 pages
File Size : 43,24 MB
Release : 2014-10-03
Category : NATURE
ISBN : 9781316073216
A comprehensive and critical overview of the major genetically modified mouse lines used to model human neurobehavioral disorders.
Author : W. E. Crusio
Publisher :
Page : 0 pages
File Size : 49,95 MB
Release : 2013
Category : Behavior genetics
ISBN :
"The first volume in the new Cambridge Handbooks in Behavioral Genetics, Behavioral Genetics of the Mouse provides baseline information on normal behaviors, essential in both the design of experiments using genetically-modified or pharmacologically-treated animals, and in the interpretation and analyses of the results obtained. Offering a comprehensive overview of the genetics of naturally-occurring variation in mouse behavior; from perception and spontaneous behaviors, such as exploration, aggression, social interactions and motor behaviors to reinforced behaviors such as the different types of learning. Also included are numerous examples of potential experimental problems, which will aid and guide researchers trying to troubleshoot their own studies. A lasting reference, the thorough and comprehensive reviews offer an easy entrance into the extensive literature in this field, and will prove invaluable to students and specialists alike"--
Author : Susanna Pietropaolo
Publisher : Cambridge University Press
Page : 471 pages
File Size : 12,36 MB
Release : 2014-09-25
Category : Science
ISBN : 131606140X
The second volume of Behavioral Genetics of the Mouse provides a comprehensive overview of the major genetically modified mouse lines used to model human neurobehavioral disorders: from disorders of perception, of autonomous and motor functions to social and cognitive syndromes, drug abuse and dependence as well as neurodegenerative pathologies. Mouse models obtained with different types of genetic manipulations (i.e. transgenic, knockout/in mice) are described in their pathological phenotypes, with a special emphasis on behavioral abnormalities. The major results obtained with many of the existing models are discussed in depth highlighting their strengths and limitations. A lasting reference, the thorough reviews offer an easy entrance into the extensive literature in this field, and will prove invaluable to students and specialists alike.
Author : Wim E. Crusio
Publisher : Cambridge University Press
Page : 361 pages
File Size : 39,44 MB
Release : 2013-04-25
Category : Science
ISBN : 1107355575
The first volume in the new Cambridge Handbooks in Behavioral Genetics series, Behavioral Genetics of the Mouse provides baseline information on normal behaviors, essential in both the design of experiments using genetically modified or pharmacologically treated animals and in the interpretation and analyses of the results obtained. The book offers a comprehensive overview of the genetics of naturally occurring variation in mouse behavior, from perception and spontaneous behaviors such as exploration, aggression, social interactions and motor behaviors, to reinforced behaviors such as the different types of learning. Also included are numerous examples of potential experimental problems, which will aid and guide researchers trying to troubleshoot their own studies. A lasting reference, the thorough and comprehensive reviews offer an easy entrance into the extensive literature in this field, and will prove invaluable to students and specialists alike.
Author : Byron C. Jones
Publisher : CRC Press
Page : 522 pages
File Size : 38,58 MB
Release : 2006-08-30
Category : Medical
ISBN : 1420003569
A complete background to concepts and principles of behavioral genetics, Neurobehavioral Genetics: Methods and Applications, Second Edition features a broad spectrum of the most current techniques in neurobehavioral genetics in a single source. International researchers incorporate several new developments in the field, including: De
Author : Jacqueline N. Crawley
Publisher : John Wiley & Sons
Page : 540 pages
File Size : 21,67 MB
Release : 2007-03-23
Category : Science
ISBN : 0471471925
Dr. Jacqueline N. Crawley, author of the First and Second Editions of What’s Wrong with My Mouse? Behavioral Phenotyping of Transgenic and Knockout Mice,continues to field calls and e-mails from molecular geneticists who ask: how do I run behavioral assays to find out what’s wrong with my mouse? Turn to What’s Wrong with My Mouse? to discover the wealth of mouse behavioral tasks and to get the guidance you need to select the best methods and necessary controls. Chapters are organized by behavioral domain, including measurements of general health, motor functions, sensory abilities, learning and memory, feeding and drinking, reproductive, social, emotional, and reward behaviors in mutant mice. Throughout the chapters, new behavioral tasks and new research discoveries have been added, bringing the Second Edition up to date with the latest science. In addition, the Second Edition includes two new chapters: "Neurodevelopment and Neurodegeneration" discusses mouse behavioral tasks relevant to neurodevelopmental diseases, such as mental retardation and autism, and to neurodegenerative diseases, such as Alzheimers, Parkinsons, Huntingtons, and amyotrophic lateral sclerosis. "Putting It All Together" recommends strategies for optimizing a battery of behavioral phenotyping tests to address your specific hypotheses about gene functions. The final chapter, "The Next Generation," examines new and emerging technologies. Throughout the book, the use of behavioral testing equipment is illustrated with photographs, diagrams, and representative data. Examples of behavioral tasks successfully applied to transgenic and knockout mouse models are provided, as well as references to the primary literature and step-by-step methods protocols. These features, along with a comprehensive index, listings of database and vendor websites, and an extensive list of references, make this book a valuable and practical resource for students and researchers.
Author : W. E. Crusio
Publisher :
Page : 362 pages
File Size : 16,59 MB
Release : 2014-05-14
Category : Nature
ISBN : 9781107342200
"The first volume in the new Cambridge Handbooks in Behavioral Genetics, Behavioral Genetics of the Mouse provides baseline information on normal behaviors, essential in both the design of experiments using genetically-modified or pharmacologically-treated animals, and in the interpretation and analyses of the results obtained. Offering a comprehensive overview of the genetics of naturally-occurring variation in mouse behavior; from perception and spontaneous behaviors, such as exploration, aggression, social interactions and motor behaviors to reinforced behaviors such as the different types of learning. Also included are numerous examples of potential experimental problems, which will aid and guide researchers trying to troubleshoot their own studies. A lasting reference, the thorough and comprehensive reviews offer an easy entrance into the extensive literature in this field, and will prove invaluable to students and specialists alike"--
Author : Valter Tucci
Publisher : John Wiley & Sons
Page : 651 pages
File Size : 10,35 MB
Release : 2016-12-27
Category : Medical
ISBN : 111854076X
The Handbook of Behavioral Genetics and Phenotyping represents an integrative approach to neurobehavioural genetics; worldwide experts in their field will review all chapters. Advanced overviews of neurobehavioural characteristics will add immense value to the investigation of animal mutants and provide unique information about the genetics and behavioural understanding of animal models, under both normal and pathological conditions. Cross-species comparisons of neurobehavioural phenotypes will pave the way for an evolutionary understanding of behaviour. Moreover, while biological sciences are progressing towards a holistic approach to investigate the complexity of organisms (i.e., “systems biology” approach), an integrated analysis of behavioural phenotyping is still lacking. The Handbook of Behavioral Genetics and Phenotyping strengthens the cross-talk within disciplines that investigate the fundamental basis of behaviour and genetics. This will be the first volume in which traditionally distant fields including genomics, behaviour, electrophysiology, neuroeconomics, and computational neuroscience, among others, are evaluated together and simultaneously accounted for during discussions of future perspectives.
Author : DRISCOLL
Publisher : Springer Science & Business Media
Page : 323 pages
File Size : 15,16 MB
Release : 2013-11-11
Category : Science
ISBN : 148996732X
Author : Fergus Craik
Publisher : Psychology Press
Page : 776 pages
File Size : 34,40 MB
Release : 2014-01-21
Category : Psychology
ISBN : 1317775066
The chapters in this volume are the edited versions of invited addresses to the XXVI International Congress of Psychology held in Montréal in August 1996. As one major goal of the Congress was to promote communication among specializations in scientific psychology, the speakers were asked to survey their research area and present their own work in a way that would be accessible to their colleagues in other areas. Another purpose of the meeting was to bring researchers together from different parts of the world, reflecting their different approaches to the scientific study of mind, brain, and behavior. Consequently, the eminent researchers who have written the twenty-six chapters included in the present volume were drawn from universities and research institutes in North America, Europe, Japan, Russia, Israel, and New Zealand. The chapters cover a range of topics in human and animal experimental psychology. The first section deals with psychobiological processes - the interplay of body and mind in determining intelligence, stress, and pain. The next five chapters address current issues in neuropsychology and neuroscience, including the neural correlates of attention and vision. A third section looks at learning processes in humans and animals, and a fourth deals with a range of topics in perception and cognition. The final five chapters take a developmental perspective, presenting theoretical and empirical analyses of the acquisition of perceptual and cognitive abilities. Overall, the collection illustrates the growing trend to break down traditional barriers between areas of experimental psychology; there are many instances of profitable interactions between researchers studying aspects of behavior and those studying the biological bases of these behaviors. The twenty-six chapters give an excellent overview of current research in scientific psychology.
