Bennett's Cardiac Arrhythmias


Book Description

Reviews of previous editions: "...a well conceived practical guide to the interpretation andtreatment of the main cardiac rhythm disturbances." —Lancet "This book presents a concise and simplified approach to thediagnosis and management of abnormalities in cardiac rhythm.... Oneof the book's strengths is the number and quality ofelectrocardiographic tracings" —New England Journal of Medicine "...this book provides an excellent foundation for all thoseinvolved in the care of arrhythmia patients" —British Journal of Hospital Medicine "…would recommend it unreservedly to anaesthetists whowish to improve their knowledge of cardiac arrhythmias" —British Journal of Anaesthesia "This book about cardiac arrhythmias is of much educationalvalue" —European Heart Journal A trusted source for junior doctors, students, nurses andcardiac technicians for over 30 years, the new edition of thisclassic reference continues the winning formula of previouseditions while at the same time incorporating essential new contenton today's most important clinical topics, including: Atrial fibrillation: ablation, drugs, rate control versusrhythm control, risk of systemic embolism, prognosis Indications for and management of implantable defibrillatorsincluding complications such as arrhythmia storms Indications for pacemaker implantation Anticoagulant therapy (for atrial fibrillation) Long QT syndromes and other channelopathies Recently-approved anti-arrhythmia drugs The 8th edition also features the latest guidelines on ECGscreening of athletes and clear guidance for anaesthetists andsurgeons dealing with patients with arrhythmias an/or implantabledevices. Rich with example ECGs and designed for ease of access toinformation, Bennett's Cardiac Arrhythmias is the referenceyou can trust to help you master arrhythmia diagnosis and provideoptimal treatment of any patient under your care.




Basis and Treatment of Cardiac Arrhythmias


Book Description

Incorporating the information related to mechanisms and treatment of cardiac arrhythmia, this book discusses genetics of arrhythmias, cell signalling molecules as potential therapeutic targets and trafficking to the membrane. These approaches and implementations of anti-arrhythmic therapy derive from many decades of research.




Anesthetic Pharmacology


Book Description

In recent years our understanding of molecular mechanisms of drug action and interindividual variability in drug response has grown enormously. Meanwhile, the practice of anesthesiology has expanded to the preoperative environment and numerous locations outside the OR. Anesthetic Pharmacology: Basic Principles and Clinical Practice, 2nd edition, is an outstanding therapeutic resource in anesthesia and critical care: Section 1 introduces the principles of drug action, Section 2 presents the molecular, cellular and integrated physiology of the target organ/functional system and Section 3 reviews the pharmacology and toxicology of anesthetic drugs. The new Section 4, Therapeutics of Clinical Practice, provides integrated and comparative pharmacology and the practical application of drugs in daily clinical practice. Edited by three highly acclaimed academic anesthetic pharmacologists, with contributions from an international team of experts, and illustrated in full colour, this is a sophisticated, user-friendly resource for all practitioners providing care in the perioperative period.




Cardiac Arrhythmias, Pacing and Sudden Death


Book Description

This book provides up-to-date, user-friendly and comprehensive guidance on the evaluation, diagnosis, and medical and surgical treatment of cardiac arrhythmias. This ensures that that this title aids every trainee and practicising cardiologist, cardiac electrophysiologist, cardiac surgeon, vascular surgeon, diabetologist, cardiac radiologist and any physician who manages cardiac patients. Cardiovascular Medicine: Cardiac Arrhythmias, Pacing and Sudden Death covers every aspect of cardiac arrhythmias, from cardiac signs and symptoms through imaging and the genetic basis for disease to surgery, interventions, treatment and preventive cardiology. This coverage is presented with consistent chapter organization, clear design, and engaging text that includes user-friendly features such as tables, lists and treatment boxes.




Heart Rate and Rhythm


Book Description

Pathological heart rhythms are a major health issue. In this book experts from various fields provide an important context for understanding the complicated molecular and cellular mechanisms that underlie normal and pathophysiological cardiac rhythms. Individual chapters cover a full range of topics, including the ionic basis of pacemaking, the role of specific channels and transporters in sinoatrial node pacemaking, altered intracellular Ca2+ handling in response to disease, computer modeling of the action potentials of pacemaker and working cardiomyocytes, genetic and molecular basis of inherited arrhythmias and a review of established and novel antiarrhythmic agents. Due to the key importance of the specialized pacemaker cells and tissue (sinoatrial and atrioventricular nodes) in maintaining heart rate and rhythm, special emphasis is placed on the peculiar electrophysiology of these cells.




Transgenic models of cardiac arrhythmias and sudden death


Book Description

Cardiac arrhythmias secondary to hereditary genetic disorders are increasingly recognized as a cause for sudden cardiac death in the general population. Mutations in a large number of genes encoding ion channels and proteins involved in cell-cell coupling have been identified in affected patient populations. Furthermore, genetic defects in other proteins directly or indirectly influencing cardiac electrophysiological properties have been shown to be involved. In-depth studies of the mechanisms underlying the observed electrophysiological abnormalities are often limited in patients carrying these mutations. Transgenic mouse models incorporating the genetic defect in question have been successful in studying genotype-phenotype correlations and have provided important insight into the underlying electrophysiological, biophysical, and molecular mechanisms. In this Research Topic Issue, an overview is presented of the knowledge and insight obtained from various transgenic models of cardiac electrophysiology so far, and how further research in this field may be of additional benefit for the future identification, risk-stratification, and treatment of patients with inherited cardiac arrhythmias and sudden death.




Ion Channel Trafficking and Cardiac Arrhythmias


Book Description

A well-adjusted expression of cardiac ion channels at the sarcolemma is of crucial importance for normal action potential formation and thus cardiac function. The cellular processes that transport channel proteins from the endoplasmic reticulum towards specified regions on the sarcolemmal membrane, and subsequently take them from the plasma membrane to the protein degradation machinery are commonly known as trafficking. The research field recognizes that aberrant channel trafficking stands at the basis of many congenital and acquired arrhythmias. The collection of papers in this eBook provides state-of-the-art insight into the world of ion channel trafficking research.




Guide to Canine and Feline Electrocardiography


Book Description

Guide to Canine and Feline Electrocardiography offers a comprehensive and readable guide to the diagnosis and treatment of abnormal heart rhythms in cats and dogs. Covers all aspects of electrocardiography, from basics to advanced concepts of interest to specialists Explains how to obtain high-quality electrocardiograms Offers expert insight and guidance on the diagnosis and treatment of simple and complex arrhythmias alike Features numerous case examples, with electrocardiograms and Holter monitor recordings Shows the characteristics of normal and abnormal heart rhythms in dogs and cats Includes access to a website with self-assessment questions and the appendices and figures from the book




Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases E-Book


Book Description

After thirty five years, Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases, 8th Edition is still the reference of choice for comprehensive, global guidance on diagnosing and treating the most challenging infectious diseases. Drs. John E. Bennett and Raphael Dolin along with new editorial team member Dr. Martin Blaser have meticulously updated this latest edition to save you time and to ensure you have the latest clinical and scientific knowledge at your fingertips. With new chapters, expanded and updated coverage, increased worldwide perspectives, and many new contributors, Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases, 8th Edition helps you identify and treat whatever infectious disease you see. Get the answers to any questions you have with more in-depth coverage of epidemiology, etiology, pathology, microbiology, immunology, and treatment of infectious agents than you’ll find in any other ID resource. Apply the latest knowledge with updated diagnoses and treatments for currently recognized and newly emerging infectious diseases, such as those caused by avian and swine influenza viruses. Put the latest knowledge to work in your practice with new or completely revised chapters on Influenza (new pandemic strains); New Middle East Respiratory Syndrome (MERS) Virus; Probiotics; Antibiotics for resistant bacteria; Antifungal drugs; New Antivirals for hepatitis B and C; Clostridium difficile treatment; Sepsis; Advances in HIV prevention and treatment; Viral gastroenteritis; Lyme Disease; Helicobacter pylori; Malaria; Infections in immunocompromised hosts; Immunization (new vaccines and new recommendations); and Microbiome. Benefit from fresh perspectives and expanded global insights from an expanded team of American and International contributors. Martin Blaser, MD, a leading expert and Muriel G. and George W. Singer Professional of Translational Medicine at New York University School of Medicine, joins veteran PPID editors John E. Bennett, MD, and Raphael Dolin, MD to continue a legacy of excellence. Find and grasp the information you need easily and rapidly with newly added chapter summaries.




Aspects of the Cytoskeleton


Book Description

This volume provides an overview of the cytoskeleton particularly on the fundamental role the cytoskeleton plays in the regulation of cell structure and function. This book represents new trends in cytoskeletal research that go beyond the traditional approach of identifying new proteins in the cytoskeleton, but actually define how these proteins interact with signaling pathways. While the major emphasis in this volume remains on the microfilament structure, some discussion has been included in this volume to illustrate the similarities and differences between the three cytoskeletal elements namely the actin microfilament, the intermediate filaments and the microtubules.