Author : James Edwin Bailey
Publisher :
Page : 984 pages
File Size : 24,1 MB
Release : 1986
Category : Biochemical engineering
ISBN : 9780070666016
Biochemical Engineering Fundamentals, 2/e, combines contemporary engineering science with relevant biological concepts in a comprehensive introduction to biochemical engineering. The biological background provided enables students to comprehend the major problems in biochemical engineering and formulate effective solutions.
Author : Rajiv Dutta
Publisher : Springer
Page : 0 pages
File Size : 35,80 MB
Release : 2010-11-19
Category : Technology & Engineering
ISBN : 9783642096747
The biology, biotechnology, chemistry, pharmacy and chemical engineering students at various universtiy and engineering institutions are required to take the Biochemical Engineering course either as an elective or compulsory subject. This book is written keeping in mind the need for a text book on afore subject for students from both engineering and biology backgrounds. The main feature of this book is that it contains the solved problems, which help the students to understand the subject better. The book is divided into three sections: Enzyme mediated bioprocess, whole cell mediated bioprocess and the engineering principle in bioprocess. Dr. Rajiv Dutta is Professor in Biotechnology and Director, Amity Institute of Biotechnology, Lucknow. He earned his M. Tech. in Biotechnology and Engineering from the Department of Chemical Engineering, IIT, Kharagpur and Ph.D. in Bioelectronics from BITS, Pilani. He has taught Biochemical Engineering and Biophysics to B.E., M.E. and M.Sc. level student carried out advanced research in the area of Ion channels at the Department of Botany at Oklahoma State University, Stillwater and Department of Biological Sciences at Purdue University, West Lafayette, IN. He also holds the position of Nanion Technologies Adjunct Research Professor at Research Triangle Institute, RTP, NC. He had received various awards including JCI Outstanding Young Person of India and ISBEM Dr. Ramesh Gulrajani Memorial Award 2006 for outstanding research in electro physiology.
Author : John Villadsen
Publisher : John Wiley & Sons
Page : 574 pages
File Size : 24,11 MB
Release : 2015-10-07
Category : Science
ISBN : 3527697462
A thorough introduction to the basics of bioengineering, with a focus on applications in the emerging "white" biotechnology industry. As such, this latest volume in the "Advanced Biotechnology" series covers the principles for the design and analysis of industrial bioprocesses as well as the design of bioremediation systems, and several biomedical applications. No fewer than seven chapters introduce stoichiometry, kinetics, thermodynamics and the design of ideal and real bioreactors, illustrated by more than 50 practical examples. Further chapters deal with the tools that enable an understanding of the behavior of cell cultures and enzymatically catalyzed reactions, while others discuss the analysis of cultures at the level of the cell, as well as structural frameworks for the successful scale-up of bioreactions. In addition, a short survey of downstream processing options and the control of bioreactions is given. With contributions from leading experts in industry and academia, this is a comprehensive source of information peer-reviewed by experts in the field.
Author : Shigeo Katoh
Publisher : John Wiley & Sons
Page : 328 pages
File Size : 21,90 MB
Release : 2015-02-02
Category : Technology & Engineering
ISBN : 3527684999
Completely revised, updated, and enlarged, this second edition now contains a subchapter on biorecognition assays, plus a chapter on bioprocess control added by the new co-author Jun-ichi Horiuchi, who is one of the leading experts in the field. The central theme of the textbook remains the application of chemical engineering principles to biological processes in general, demonstrating how a chemical engineer would address and solve problems. To create a logical and clear structure, the book is divided into three parts. The first deals with the basic concepts and principles of chemical engineering and can be read by those students with no prior knowledge of chemical engineering. The second part focuses on process aspects, such as heat and mass transfer, bioreactors, and separation methods. Finally, the third section describes practical aspects, including medical device production, downstream operations, and fermenter engineering. More than 40 exemplary solved exercises facilitate understanding of the complex engineering background, while self-study is supported by the inclusion of over 80 exercises at the end of each chapter, which are supplemented by the corresponding solutions. An excellent, comprehensive introduction to the principles of biochemical engineering.
Author : Debabrata Das
Publisher : CRC Press
Page : 185 pages
File Size : 30,70 MB
Release : 2021-01-11
Category : Medical
ISBN : 1000225437
Biochemical engineering mostly deals with the most complicated life systems as compared with chemical engineering. A fermenter is the heart of biochemical processes. It is essential to operate a system properly. A description of enzymatic reaction kinetics is followed by cell growth kinetics to determine several kinetic parameters. Operations and analyses of several biochemical processes are included to determine their special. The book also covers the determination of several operational parameters, such as volumetric mass transfer coefficient, mixing time, death rate constant, chemical oxygen demand, and heat of combustion. This book provides a novel description of the experimental protocol to find out several operational parameters of biochemical processes. A comprehensive collection of numerous experiments based on fundamentals, it focuses on the determination of not only the characteristics of raw materials but also other essential parameters required for the operation of biochemical processes. It also emphasizes the applicability of the analysis to various processes. Equipped with illustrative diagrams, neat flowcharts, and exhaustive tables, the book is ideal for young researchers, teachers, and scientists working towards developing a solid understanding of the experimental aspects of biochemical engineering.
Author : K. Dane Wittrup
Publisher : MIT Press
Page : 593 pages
File Size : 14,33 MB
Release : 2020-01-07
Category : Science
ISBN : 0262042657
A comprehensive presentation of essential topics for biological engineers, focusing on the development and application of dynamic models of biomolecular and cellular phenomena. This book describes the fundamental molecular and cellular events responsible for biological function, develops models to study biomolecular and cellular phenomena, and shows, with examples, how models are applied in the design and interpretation of experiments on biological systems. Integrating molecular cell biology with quantitative engineering analysis and design, it is the first textbook to offer a comprehensive presentation of these essential topics for chemical and biological engineering. The book systematically develops the concepts necessary to understand and study complex biological phenomena, moving from the simplest elements at the smallest scale and progressively adding complexity at the cellular organizational level, focusing on experimental testing of mechanistic hypotheses. After introducing the motivations for formulation of mathematical rate process models in biology, the text goes on to cover such topics as noncovalent binding interactions; quantitative descriptions of the transient, steady state, and equilibrium interactions of proteins and their ligands; enzyme kinetics; gene expression and protein trafficking; network dynamics; quantitative descriptions of growth dynamics; coupled transport and reaction; and discrete stochastic processes. The textbook is intended for advanced undergraduate and graduate courses in chemical engineering and bioengineering, and has been developed by the authors for classes they teach at MIT and the University of Minnesota.
Author : Douglas A. Lauffenburger
Publisher : Oxford University Press
Page : 376 pages
File Size : 43,90 MB
Release : 1996-01-11
Category : Science
ISBN : 0190283068
Receptors: Models for Binding, Trafficking, and Signaling bridges the gap between chemical engineering and cell biology by lucidly and practically demonstrating how a mathematical modeling approach combined with quantitative experiments can provide enhanced understanding of cell phenomena involving receptor/ligand interactions. In stressing the need for a quantitative understanding of how receptor-mediated cell functions depend on receptor and ligand properties, the book offers comprehensive treatments of both basic and state-of-the-art model frameworks that span the entire spectrum of receptor processes--from fundamental cell surface binding, intracellular trafficking, and signal transduction events to the cell behavioral functions they govern, including proliferation, adhesion, and migration. The book emphasizes mechanistic models that are accessible to experimental testing and includes detailed examples of important contemporary issues. This much-needed book introduces chemical engineers and bioengineers to important problems in receptor biology and familiarizes cell biologists with the insights that can be gained from engineering analysis and synthesis. As such, chemical engineers, researchers, and advanced students in the fields of biotechnology, biomedical sciences, bioengineering, and molecular cell biology will find this book to be conceptually rich, timely, and useful.
Author : Wei-Shou Hu
Publisher : John Wiley & Sons
Page : 502 pages
File Size : 50,84 MB
Release : 2017-11-13
Category : Science
ISBN : 1119159024
This book is a short introduction to the engineering principles of harnessing the vast potential of microorganisms, and animal and plant cells in making biochemical products. It was written for scientists who have no background in engineering, and for engineers with minimal background in biology. The overall subject dealt with is process. But the coverage goes beyond the process of biomanufacturing in the bioreactor, and extends to the factory of cell’s biosynthetic machinery. Starting with an overview of biotechnology and organism, engineers are eased into biochemical reactions and life scientists are exposed to the technology of production using cells. Subsequent chapters allow engineers to be acquainted with biochemical pathways, while life scientist learn about stoichiometric and kinetic principles of reactions and cell growth. This leads to the coverage of reactors, oxygen transfer and scale up. Following three chapters on biomanufacturing of current and future importance, i.e. cell culture, stem cells and synthetic biology, the topic switches to product purification, first with a conceptual coverage of operations used in bioseparation, and then a more detailed analysis to provide a conceptual understanding of chromatography, the modern workhorse of bioseparation. Drawing on principles from engineering and life sciences, this book is for practitioners in biotechnology and bioengineering. The author has used the book for a course for advanced students in both engineering and life sciences. To this end, problems are provided at the end of each chapter.
Author : Pauline M. Doran
Publisher : Elsevier
Page : 455 pages
File Size : 28,3 MB
Release : 1995-04-03
Category : Science
ISBN : 0080528120
The emergence and refinement of techniques in molecular biology has changed our perceptions of medicine, agriculture and environmental management. Scientific breakthroughs in gene expression, protein engineering and cell fusion are being translated by a strengthening biotechnology industry into revolutionary new products and services. Many a student has been enticed by the promise of biotechnology and the excitement of being near the cutting edge of scientific advancement. However, graduates trained in molecular biology and cell manipulation soon realise that these techniques are only part of the picture. Reaping the full benefits of biotechnology requires manufacturing capability involving the large-scale processing of biological material. Increasingly, biotechnologists are being employed by companies to work in co-operation with chemical engineers to achieve pragmatic commercial goals. For many years aspects of biochemistry and molecular genetics have been included in chemical engineering curricula, yet there has been little attempt until recently to teach aspects of engineering applicable to process design to biotechnologists.This textbook is the first to present the principles of bioprocess engineering in a way that is accessible to biological scientists. Other texts on bioprocess engineering currently available assume that the reader already has engineering training. On the other hand, chemical engineering textbooks do not consider examples from bioprocessing, and are written almost exclusively with the petroleum and chemical industries in mind. This publication explains process analysis from an engineering point of view, but refers exclusively to the treatment of biological systems. Over 170 problems and worked examples encompass a wide range of applications, including recombinant cells, plant and animal cell cultures, immobilised catalysts as well as traditional fermentation systems.* * First book to present the principles of bioprocess engineering in a way that is accessible to biological scientists* Explains process analysis from an engineering point of view, but uses worked examples relating to biological systems* Comprehensive, single-authored* 170 problems and worked examples encompass a wide range of applications, involving recombinant plant and animal cell cultures, immobilized catalysts, and traditional fermentation systems* 13 chapters, organized according to engineering sub-disciplines, are groupled in four sections - Introduction, Material and Energy Balances, Physical Processes, and Reactions and Reactors* Each chapter includes a set of problems and exercises for the student, key references, and a list of suggestions for further reading* Includes useful appendices, detailing conversion factors, physical and chemical property data, steam tables, mathematical rules, and a list of symbols used* Suitable for course adoption - follows closely curricula used on most bioprocessing and process biotechnology courses at senior undergraduate and graduate levels.
Author : John Enderle
Publisher : Elsevier
Page : 1141 pages
File Size : 22,11 MB
Release : 2005-05-20
Category : Science
ISBN : 0080473148
Under the direction of John Enderle, Susan Blanchard and Joe Bronzino, leaders in the field have contributed chapters on the most relevant subjects for biomedical engineering students. These chapters coincide with courses offered in all biomedical engineering programs so that it can be used at different levels for a variety of courses of this evolving field. Introduction to Biomedical Engineering, Second Edition provides a historical perspective of the major developments in the biomedical field. Also contained within are the fundamental principles underlying biomedical engineering design, analysis, and modeling procedures. The numerous examples, drill problems and exercises are used to reinforce concepts and develop problem-solving skills making this book an invaluable tool for all biomedical students and engineers. New to this edition: Computational Biology, Medical Imaging, Genomics and Bioinformatics.* 60% update from first edition to reflect the developing field of biomedical engineering* New chapters on Computational Biology, Medical Imaging, Genomics, and Bioinformatics* Companion site: http://intro-bme-book.bme.uconn.edu/* MATLAB and SIMULINK software used throughout to model and simulate dynamic systems* Numerous self-study homework problems and thorough cross-referencing for easy use
