The Neurobiological Basis of Suicide


Book Description

With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.




Reducing Suicide


Book Description

Every year, about 30,000 people die by suicide in the U.S., and some 650,000 receive emergency treatment after a suicide attempt. Often, those most at risk are the least able to access professional help. Reducing Suicide provides a blueprint for addressing this tragic and costly problem: how we can build an appropriate infrastructure, conduct needed research, and improve our ability to recognize suicide risk and effectively intervene. Rich in data, the book also strikes an intensely personal chord, featuring compelling quotes about people's experience with suicide. The book explores the factors that raise a person's risk of suicide: psychological and biological factors including substance abuse, the link between childhood trauma and later suicide, and the impact of family life, economic status, religion, and other social and cultural conditions. The authors review the effectiveness of existing interventions, including mental health practitioners' ability to assess suicide risk among patients. They present lessons learned from the Air Force suicide prevention program and other prevention initiatives. And they identify barriers to effective research and treatment. This new volume will be of special interest to policy makers, administrators, researchers, practitioners, and journalists working in the field of mental health.




Suicide in Children and Adolescents


Book Description

In an epoch when rates of death and illness among the young have steadily decreased in the face of medical progress, the persistently high rates of youth suicide and suicide attempts around the world remain a tragic irony and a challenge to both our clinical practice and theoretical understanding. How can these deaths be prevented? Can they be anticipated? Are there perceptible patterns of risk and vulnerability? What role do families, gender, culture, and biology play? What are the treatments for and outcomes of suicide attempters? To address these questions, experts from around the world in all areas of psychiatry, from epidemiology, neurobiology, genetics and psychotherapy, have brought together their current findings in Suicide in Children and Adolescents.




Behavioral Neurobiology of Suicide and Self Harm


Book Description

This book reviews the recent research into biological aspects of suicide behavior and outlines each of the varied, recent approaches to prevent suicide. Suicidal behavior, perhaps, is the most complex behavior that combines biological, social, and psychological factors. A new frontier and new opportunities are opening with the technologies of data acquisition and data analysis. Personalized models based on digital phenotype could provide promising strategies for preventing suicide.




Oxford Textbook of Suicidology and Suicide Prevention


Book Description

Part of the authoritative Oxford Textbooks in Psychiatry series, the new edition of the Oxford Textbook of Suicidology and Suicide Prevention remains a key text in the field of suicidology, fully updated with new chapters devoted to major psychiatric disorders and their relation to suicide.




Understanding the Complex Phenomenon of Suicide: From Research to Clinical Practice


Book Description

Suicide is undoubtedly a worldwide major challenge for the public health. It is estimated that more than 150,000 persons in Europe die as a result of suicide every year and in several European countries suicide represents the principal cause of death among young people aged 14–25 years. It is true that suicide is a complex (and yet not fully understood) phenomenon and may be determined by the interaction between various factors, such as neurobiology, personal and familiar history, stressful events, sociocultural environment, etc. The suicide is always a plague for the population at risk and one of the most disgraceful events for a human being. Moreover, it implies a lot of pain often shared by the relatives and persons who are close to suicide subjects. Furthermore, it has been widely demonstrated that the loss of a subject due to suicide may be one of the most distressing events that may occur in mental health professionals resulting in several negative consequences, such as burnout, development of psychiatric symptoms and lower quality of life and work productivity. All considered, it is clear that the suicide prevention is a worldwide priority and every effort should be made in order to improve the early recognition of imminent suicide, manage suicidal subjects, and strengthen suicide prevention strategies. In our opinion, the first step of prevention is the improvement of knowledge in the field: this was the aim of this present special issue on Frontiers in Psychiatry. In this special issue, several papers have contributed to the suicide knowledge from several viewpoints and we hope that this will contribute to improve and disseminate knowledge on this topic.




Biological Aspects of Suicidal Behavior


Book Description

Suicide is one of the most important causes of death in modern societies. To develop more effective preventive measures, we have to be aware of and learn more about its neurobiological foundations. In recent years, the tools of modern neurosciences have increasingly been utilized to characterize the pathophysiology of complex human behaviors such as suicide. To improve suicide risk assessment and suicide prevention, a better understanding of its pathophysiology is crucial. This includes research from a variety of disciplines such as neuropsychological, psychosocial and cultural studies but also findings from biochemistry, neuropathology, electrophysiology, immunology, neuroimaging, genetics, and epigenetics. Important results have, for example, been obtained in the field of gene-environment interaction and suicidal behavior. We have just begun to understand how early-life adversity may increase suicide risk by epigenetic mechanisms. Based on such insights, novel therapeutic interventions and preventive measures can be developed. Furthermore, a better understanding of the pathophysiological mechanisms involved in suicidal behavior could reveal the mechanism of compounds like lithium salts. In this book, suicidal behavior and its prevention is discussed by international experts in the light of the most recent results from a broad spectrum of neurosciences.




The International Handbook of Suicide and Attempted Suicide


Book Description

Recent research in the area of suicidology has provided significant new insights in the epidemiological,psychopathological,and biological characteristics of suicidal behaviour. The International Handbook of Suicide and Attempted Suicide is the first book to bring together this expertise and translate it into practical guidelines for those responsible for policy issues and for those involved in the treatment and prevention of suicidal behaviour. Leading international authorities provide a truly comprehensive and research-based reference to understanding, treating, and preventing suicidal behaviour. They explore concepts and theories which best guide work within this field and detail key research which has supported conceptual developments, preventive interventions and clinical treatment. "No self-respecting worker in deliberate self-harm and suicide prevention, either clinical or research, can afford to be without access to this comprehensive handbook - possession and regular use, may well become a marker of serious involvement in the subject! ...This is the most comprehensive, up-to-date, informative and well-written source of information on sucide and suicidal behaviour...an invaluable work of reference which will be essential for clinicians and researchers for many years to come." —Andrew Sims, Emeritus Professor of Psychiatry, St James's University Hospital, Leeds, UK - British Journal of Psychiatry




The Oxford Handbook of Suicide and Self-Injury


Book Description

Suicide is a perplexing human behavior that remains among the leading causes of death worldwide, responsible for more deaths each year than all wars, genocide, and homicide combined. Although suicide and other forms of self-injury have baffled scholars and clinicians for thousands of years, the past few decades have brought significant leaps in our understanding of these behaviors. This volume provides a comprehensive summary of the most important and exciting advances in our understanding of suicide and self-injury and our ability to predict and prevent it. Comprised of a formidable who's who in the field, the handbook covers the full spectrum of topics in suicide and self-injury across the lifespan, including the classification of different self-injurious behaviors, epidemiology, assessment techniques, and intervention. Chapters probe relevant issues in our society surrounding suicide, including assisted suicide and euthanasia, suicide terrorism, overlap between suicidal behavior and interpersonal violence, ethical considerations for suicide researchers, and current knowledge on survivors of suicide. The most comprehensive handbook on suicide and self-injury to date, this volume is a must-read text for graduate students, fellows, academic and research psychologists, and other researchers working in the brain and behavioral sciences.




Suicide Prevention


Book Description

A practical and easy-to-use guide for healthcare professionals on the prevention, assessment and treatment of people at risk of suicide.