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Interstitial Hyperthermia: Physics, Biology and Clinical Aspects

Author : M. Urano

Publisher : CRC Press

Page : 362 pages

File Size : 42,70 MB

Release : 2023-01-06

Category : Medical

ISBN : 1466564822

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Book Description

In the last decade the use of interstitial microwave antennas to deliver localized and controlled power to deep-seated tumours has been explored in institutes around the world. Simultaneously the field of brachytherapy also progressed as clinicans began to develop new implantation approaches for a variety of tumour sites, thereby promoting the insertion of catheters which could serve as conduits for the insterstitial microwave applicators. Although the challenges presented by deep-seated tumours have not been solved, the developments in the field of brachytherapy and the implantation of interstitial applicators for hyperthermia are such that a volume dedicated to this approach is warranted. This third volume in the series "Hyperthermia and Oncology" provides insight in and updated information on various aspects of interstitial hyperthermia. It aims to serve as a guide for clinicians who are either already working in the field or who wish to implement this treatment. It also provides basic aspects to physicists and biologists who are interested in the field of hyperthermic treatment.



Hyperthermia In Cancer Treatment: A Primer

Author : Gian F. Baronzio

Publisher : Springer Science & Business Media

Page : 382 pages

File Size : 30,71 MB

Release : 2008-05-08

Category : Medical

ISBN : 0387334416

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Book Description

Following an introductory overview, Hyperthermia In Cancer Treatment: A Primer comprehensively describes the biological reasons for associating hyperthermia with radiation and chemotherapy and the biological and clinical effects of hyperthermia on cancerous and normal tissues. The volume’s 20 chapters are arranged in three principal parts: physical and methodological studies, biologic principles, and clinical studies.



Biological, Physical and Clinical Aspects of Hyperthermia

Author : Bhudatt R. Paliwal

Publisher : American Institute of Physics

Page : 506 pages

File Size : 37,25 MB

Release : 1988

Category : Medical

ISBN :

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Book Description

While the establishment of hyperthermia as a routine therapy awaits the results of ongoing controlled clinical trials, the advancement in biological sciences, physics and engineering, clinical physics and dosimetry, as well as clinical implementation continues to make advances. A first attempt to document these advances was made by Dr. Gilbert H. Nussbaum in the Medical Physics Monograph No. 8 of the American Association of Physicists in Medicine, published by the American Institute of Physics in 1982. This monograph is an extension of the above work. The material is divided into six catagories: Hyperthermia Biology, Physics and Engineering, Clinical Physics, Dosimetry and Modeling, Analysis of Clinical Results, and Quality Assurance. There are numerous methods of inducing hyperthermia and there are also equally numerous clinical strategies as expected in an experimental modality. A conscious effort has been made to document the basic information and thus provide an objective learning tool. The material contained herein will be of interest to biologists, physicists, engineers, and physicians who are actively involved in the field of hyperthermia, as well as to those who are anxious to learn about this new field. Some sections provide extremely practical information needed in the routine delivery of treatments and, therefore, will be of benefit to nurses and technologists. We also believe that this material provides insight and guidance for future research.



Whole Body Hyperthermia: Biological and Clinical Aspects

Author : Michel Gautherie

Publisher : Springer Science & Business Media

Page : 218 pages

File Size : 49,57 MB

Release : 2012-12-06

Category : Medical

ISBN : 3642845967

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Book Description

1. 1 Background neoplastic diseases which are currently refractory to conventional therapy. All aspects of both preclinical Anticancer effects of elevated (noncauterizing) tem and clinical WBH, ranging from molecular biology perature were first observed in ancient Egyptian times and physiology to WBH methodologies and clinical (Oleson and Dewhirst 1983). Hippocrates trials, will be comprehensively reviewed. It is our in (460-377 B. C. ) later incorporated fever therapy into a tention to provide the reader with a definitive resource homeopathic approach to disease (Le. , treating a dis of to evaluate the current status and future potential ease with a symptom of that disease). In the fourth WBH. In so doing, we will attempt to present the vari century, Refus of Ephesus advocated the use of fever ous perspectives and insights derived from the efforts induction to treat malignant diseases (Kluger 1980). of investigators throughout the world. We hope this In the nineteenth century tumor regressions accompa will encourage an expanded investigative commitment nying high fevers were reported both by Busch and to this exciting and innovative approach to cancer Bruns (Busch 1866; Bruns 1888). At the end of the therapy.



Thermoradiotherapy and Thermochemotherapy

Author : M.Heinrich Seegenschmiedt

Publisher : Springer Science & Business Media

Page : 479 pages

File Size : 39,16 MB

Release : 2012-12-06

Category : Medical

ISBN : 3642578586

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Book Description

Hyperthermia has been found to be of great benefit in combination with radiation therapy or chemotherapy in the management of patients with difficult and com plicated tumor problems. It has been demonstrated to increase the efficacy, of ionising radiation when used locally but also has been of help in combination with systemic chemotherapy where hyperthermia is carried out to the total body. Problems remain with regard to maximizing the effects of hyperthermia as in fluenced by blood flow, heat loss, etc. The present volume defines the current knowledge relative to hyperthermia with radiation therapy and/or chemotherapy, giving a comprehensive overview of its use in cancer management. Philadelphia/Hamburg, June 1995 L.W. BRADY H.-P. HEILMANN Preface In an attempt to overcome tumor resistance, hypoxia, or unfavorable tumor condi tions, oncological research has come to focus on gene therapy, immunotherapy, new cytotoxic agents, and increasingly sophisticated radiotherapy. Radiation research has been directed towards heavy particle therapy and modification of the radiation response by either protecting or sensitizing agents. Improved dose localization using rotational or conformal strategies has also been implemented. Recently, changes in radiation fractionation schedules have shown promise of better results. Hyperthermia in cancer therapy can be viewed similarly as another means to increase the sensitivity of tumors to radio- and chemotherapy.



Heat Transfer and Fluid Flow in Biological Processes

Author : Sid M. Becker

Publisher : Academic Press

Page : 428 pages

File Size : 11,1 MB

Release : 2014-12-31

Category : Science

ISBN : 0124079008

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Book Description

Heat Transfer and Fluid Flow in Biological Processes covers emerging areas in fluid flow and heat transfer relevant to biosystems and medical technology. This book uses an interdisciplinary approach to provide a comprehensive prospective on biofluid mechanics and heat transfer advances and includes reviews of the most recent methods in modeling of flows in biological media, such as CFD. Written by internationally recognized researchers in the field, each chapter provides a strong introductory section that is useful to both readers currently in the field and readers interested in learning more about these areas. Heat Transfer and Fluid Flow in Biological Processes is an indispensable reference for professors, graduate students, professionals, and clinical researchers in the fields of biology, biomedical engineering, chemistry and medicine working on applications of fluid flow, heat transfer, and transport phenomena in biomedical technology. - Provides a wide range of biological and clinical applications of fluid flow and heat transfer in biomedical technology - Covers topics such as electrokinetic transport, electroporation of cells and tissue dialysis, inert solute transport (insulin), thermal ablation of cancerous tissue, respiratory therapies, and associated medical technologies - Reviews the most recent advances in modeling techniques



Scientific and Clinical Applications of Magnetic Carriers

Author : Urs Häfeli

Publisher : Springer Science & Business Media

Page : 618 pages

File Size : 47,11 MB

Release : 2013-11-11

Category : Science

ISBN : 1475764820

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Book Description

The discovery of uniform latex particles by polymer chemists of the Dow Chemical Company nearly 50 years ago opened up new exciting fields for scientists and physicians and established many new biomedical applications. Many in vitro diagnostic tests such as the latex agglutination tests, analytical cell and phagocytosis tests have since become rou tine. They were all developed on the basis of small particles bound to biological active molecules and fluorescent and radioactive markers. Further developments are ongoing, with the focus now shifted to applications of polymer particles in the controlled and di rected transport of drugs in living systems. Four important factors make microspheres interesting for in vivo applications: First, biocompatible polymer particles can be used to transport known amounts of drug and re lease them in a controlled fashion. Second, particles can be made of materials which bio degrade in living organisms without doing any harm. Third, particles with modified surfaces are able to avoid rapid capture by the reticuloendothelial system and therefore en hance their blood circulation time. Fourth, combining particles with specific molecules may allow organ-directed targeting.



Hyperthermia and Cancer

Author : George M. Hahn

Publisher : Springer

Page : 312 pages

File Size : 19,23 MB

Release : 1982-10-31

Category : Medical

ISBN :

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Book Description

Hyperthermia as a tool for the treatment of malignant disease is rapidly becoming a clinical reality. In this book I am attempting to summarize the known biological and physical underpinnings that have led to this development. I also present a compilation of existing clinical results, limited as these are. My aim is to provide oncologists and other physicians with up-to-date information on this modality, which is both new and old, as well as to make available to biologists, physicists and engineers sum maries of currently available information on specific areas of hyperthermic research. Many people have helped me with this book. Specifically, thanks are due to Drs. William Dewey, Jean Dutreix, Peter Fessenden, Gloria Li, and Jane Marmor. Their suggestions have been invaluable. I hope that not too many errors and omissions have crept into the volume, but in any case, for these I have only myself to blame. I also wish to express my appreciation to David Betten and Marie Graham for their help. Most of this material was written while I was on sabbatical leave on the shores of Lake Atitlan in Guatemala. There I enjoyed the hospitality of a gracious, friendly, and proud people who deserve better than fate seems to have in store for them.





Theory and Applications of Heat Transfer in Humans, 2 Volume Set

Author : Devashish Shrivastava

Publisher : John Wiley & Sons

Page : 897 pages

File Size : 28,87 MB

Release : 2018-07-02

Category : Science

ISBN : 1119127300

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Book Description

An authoritative guide to theory and applications of heat transfer in humans Theory and Applications of Heat Transfer in Humans 2V Set offers a reference to the field of heating and cooling of tissue, and associated damage. The author—a noted expert in the field—presents, in this book, the fundamental physics and physiology related to the field, along with some of the recent applications, all in one place, in such a way as to enable and enrich both beginner and advanced readers. The book provides a basic framework that can be used to obtain ‘decent’ estimates of tissue temperatures for various applications involving tissue heating and/or cooling, and also presents ways to further develop more complex methods, if needed, to obtain more accurate results. The book is arranged in three sections: The first section, named ‘Physics’, presents fundamental mathematical frameworks that can be used as is or combined together forming more complex tools to determine tissue temperatures; the second section, named ‘Physiology’, presents ideas and data that provide the basis for the physiological assumptions needed to develop successful mathematical tools; and finally, the third section, named ‘Applications’, presents examples of how the marriage of the first two sections are used to solve problems of today and tomorrow. This important text is the vital resource that: Offers a reference book in the field of heating and cooling of tissue, and associated damage. Provides a comprehensive theoretical and experimental basis with biomedical applications Shows how to develop and implement both, simple and complex mathematical models to predict tissue temperatures Includes simple examples and results so readers can use those results directly or adapt them for their applications Designed for students, engineers, and other professionals, a comprehensive text to the field of heating and cooling of tissue that includes proven theories with applications. The author reveals how to develop simple and complex mathematical models, to predict tissue heating and/or cooling, and associated damage.