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Biomedical Membranes And (Bio)artificial Organs

Author : Dimitrios Stamatialis

Publisher : World Scientific

Page : 346 pages

File Size : 37,98 MB

Release : 2017-11-29

Category : Technology & Engineering

ISBN : 9813223987

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Book Description

This book focusses on the development of biomedical membranes and their applications for (bio)artificial organs. It covers the state of art and main challenges for applying synthetic membranes in these organs. It also highlights the importance of accomplishing an integration of engineering with biology and medicine to understand and manage the scientific, industrial, clinical and ethical aspects of these organs.The compendium consists of 11 chapters, written by world renowned experts in the fields of membrane technology, biomaterials science and technology, cell biology, medicine and engineering. Every chapter describes the clinical needs and the materials, membranes, and concepts required for the successful development of the (bio)artificial organs.This text is suitable for undergraduate and graduate students in biomedical engineering, materials science and membrane science and technology, as well as, for professionals and researchers working in these fields.



Biomaterials for Artificial Organs

Author : Michael Lysaght

Publisher : Elsevier

Page : 313 pages

File Size : 15,36 MB

Release : 2010-12-20

Category : Technology & Engineering

ISBN : 0857090844

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Book Description

The worldwide demand for organ transplants far exceeds available donor organs. Consequently some patients die whilst waiting for a transplant. Synthetic alternatives are therefore imperative to improve the quality of, and in some cases, save people's lives. Advances in biomaterials have generated a range of materials and devices for use either outside the body or through implantation to replace or assist functions which may have been lost through disease or injury. Biomaterials for artificial organs reviews the latest developments in biomaterials and investigates how they can be used to improve the quality and efficiency of artificial organs.Part one discusses commodity biomaterials including membranes for oxygenators and plasmafilters, titanium and cobalt chromium alloys for hips and knees, polymeric joint-bearing surfaces for total joint replacements, biomaterials for pacemakers, defibrillators and neurostimulators and mechanical and bioprosthetic heart valves. Part two goes on to investigate advanced and next generation biomaterials including small intestinal submucosa and other decullarized matrix biomaterials for tissue repair, new ceramics and composites for joint replacement surgery, biomaterials for improving the blood and tissue compatibility of total artificial hearts (TAH) and ventricular assist devices (VAD), nanostructured biomaterials for artificial tissues and organs and matrices for tissue engineering and regenerative medicine.With its distinguished editors and international team of contributors Biomaterials for artificial organs is an invaluable resource to researchers, scientists and academics concerned with the advancement of artificial organs. - Reviews the latest developments in biomaterials and investigates how they can be used to improve the quality and efficiency of artificial organs - Discusses commodity biomaterials including membranes for oxygenators and cobalt chromium alloys for hips and knees and polymeric joint-bearing surfaces for total joint replacements - Further biomaterials utilised in pacemakers, defibrillators, neurostimulators and mechanical and bioprosthetic heart valve are also explored



Organ Manufacturing

Author : Xiaohong Wang

Publisher : Nova Science Publishers

Page : 0 pages

File Size : 24,72 MB

Release : 2015

Category : Artificial organs

ISBN : 9781634829571

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Book Description

This is the first time that human organs, such as the heart, liver, kidney, stomach, uterus, skin, lung, pancreas and breast can be manufactured automatically and precisely for clinical transplantation, drug screening and metabolism model establishment. Headed by Professor Xiaohong Wang (also the founder and director) in the Center of Organ Manufacturing, Department of Mechanical Engineering, Tsinghua University, this group has focused on organ manufacturing for over ten years. A series of technical bottleneck problems, such as vascular and nerve system establishment in a construct, multiple cell types and material system incorporation, and stem cell sequential engagement, have been overcome one by one. Two technical approaches have been exploited extensively. One is multiple nozzle rapid prototyping (RP), additive manufacturing (AM), or three-dimension (3D) printing. The other is combined mold systems. More than 110 articles and 40 patents with a series of theories and practices have been published consequently. In the future, all the failed organs (including the brain) in the human body can be substituted easily like a small accessory part in a car. Everyone can get benefit from these techniques, which ultimately means that the lifespan of humans, therefore, can be greatly prolonged from this time point. This book examines the progress made in the field and the developments made by these researchers (and authors) in the field.



Biomedical Engineering Challenges

Author : Vincenzo Piemonte

Publisher : John Wiley & Sons

Page : 273 pages

File Size : 50,38 MB

Release : 2018-04-23

Category : Science

ISBN : 1119296048

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Book Description

An important resource that puts the focus on the chemical engineering aspects of biomedical engineering In the past 50 years remarkable achievements have been advanced in the fields of biomedical and chemical engineering. With contributions from leading chemical engineers, Biomedical Engineering Challenges reviews the recent research and discovery that sits at the interface of engineering and biology. The authors explore the principles and practices that are applied to the ever-expanding array of such new areas as gene-therapy delivery, biosensor design, and the development of improved therapeutic compounds, imaging agents, and drug delivery vehicles. Filled with illustrative case studies, this important resource examines such important work as methods of growing human cells and tissues outside the body in order to repair or replace damaged tissues. In addition, the text covers a range of topics including the challenges faced with developing artificial lungs, kidneys, and livers; advances in 3D cell culture systems; and chemical reaction methodologies for biomedical imagining analysis. This vital resource: Covers interdisciplinary research at the interface between chemical engineering, biology, and chemistry Provides a series of valuable case studies describing current themes in biomedical engineering Explores chemical engineering principles such as mass transfer, bioreactor technologies as applied to problems such as cell culture, tissue engineering, and biomedical imaging Written from the point of view of chemical engineers, this authoritative guide offers a broad-ranging but concise overview of research at the interface of chemical engineering and biology.



Tissue Engineering for Artificial Organs, 2 Volume Set

Author : Anwarul Hasan

Publisher : John Wiley & Sons

Page : 762 pages

File Size : 43,88 MB

Release : 2017-06-19

Category : Science

ISBN : 3527338632

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Book Description

A comprehensive overview of the latest achievements, trends, and the current state of the art of this important and rapidly expanding field. Clearly and logically structured, the first part of the book explores the fundamentals of tissue engineering, providing a separate chapter on each of the basic topics, including biomaterials stem cells, biosensors and bioreactors. The second part then follows a more applied approach, discussing various applications of tissue engineering, such as the replacement or repairing of skins, cartilages, livers and blood vessels, to trachea, lungs and cardiac tissues, to musculoskeletal tissue engineering used for bones and ligaments as well as pancreas, kidney and neural tissue engineering for the brain. The book concludes with a look at future technological advances. An invaluable reading for entrants to the field in biomedical engineering as well as expert researchers and developers in industry.



Transport Phenomena in Biomedical Engineering: Artifical organ Design and Development, and Tissue Engineering

Author : Kal Renganathan Sharma

Publisher : McGraw Hill Professional

Page : 510 pages

File Size : 28,35 MB

Release : 2010-07-21

Category : Technology & Engineering

ISBN : 0071663983

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Book Description

A Cutting-Edge Guide to Applying Transport Phenomena Principles to Bioengineering Systems Transport Phenomena in Biomedical Engineering: Artificial Order Design and Development and Tissue Engineering explains how to apply the equations of continuity, momentum, energy, and mass to human anatomical systems. This authoritative resource presents solutions along with term-by-term medical significance. Worked exercises illustrate the equations derived, and detailed case studies highlight real-world examples of artificial organ design and human tissue engineering. Coverage includes: Fundamentals of fluid mechanics and principles of molecular diffusion Osmotic pressure, solvent permeability, and solute transport Rheology of blood and transport Gas transport Pharmacokinetics Tissue design Bioartificial organ design and immunoisolation Bioheat transport 541 end-of-chapter exercises and review questions 106 illustrations 1,469 equations derived from first principles



Artificial Cells

Author : Thomas Ming Swi Chang

Publisher : World Scientific

Page : 482 pages

File Size : 30,26 MB

Release : 2007

Category : Medical

ISBN : 9812770372

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Book Description

50th anniversary of artificial cells -- Basic principles -- Oxygen carriers based on nanobiotechnology -- A nanobiotechnologic therapeutic that transports oxygen and remove oxygen radicals: for stroke, hemorrhagic shock and related conditions -- Nanotechnology-based artificial red blood cells (RBC's) -- Use of enzyme artificial cells for genetic enzyme defects that increase systemic substrates to toxic levels -- Enzyme artificial cells in substrate-dependent tumors and activation of prodrug -- Artificial cells for cell encapsulation -- Artificial cells containing hepatocytes and/or stem cells in regenerative medicine -- Hemoperfusion in poisoning, kidney failure, liver failure, and immunology -- Perspectives on the future of artificial cells as suggested by past research.



Biomaterials, Artificial Organs and Tissue Engineering

Author : L Hench

Publisher : Elsevier

Page : 298 pages

File Size : 47,49 MB

Release : 2005-09-27

Category : Science

ISBN : 1845690869

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Book Description

Maintaining quality of life in an ageing population is one of the great challenges of the 21st Century. This book summarises how this challenge is being met by multi-disciplinary developments of specialty biomaterials, devices, artificial organs and in-vitro growth of human cells as tissue engineered constructs.Biomaterials, Artificial Organs and Tissue Engineering is intended for use as a textbook in a one semester course for upper level BS, MS and Meng students. The 25 chapters are organized in five parts: Part one provides an introduction to living and man-made materials for the non-specialist; Part two is an overview of clinical applications of various biomaterials and devices; Part three summarises the bioengineering principles, materials and designs used in artificial organs; Part four presents the concepts, cell techniques, scaffold materials and applications of tissue engineering; Part five provides an overview of the complex socio-economic factors involved in technology based healthcare, including regulatory controls, technology transfer processes and ethical issues. - Comprehensive introduction to living and man-made materials - Looks at clinical applications of various biomaterials and devices - Bioengineering principles, materials and designs used in artificial organs are summarised



Basic Transport Phenomena In Biomedical Engineering

Author : Ronald L. Fournier

Publisher : CRC Press

Page : 336 pages

File Size : 19,24 MB

Release : 1998-08-01

Category : Medical

ISBN : 9781560327080

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Book Description

This text combines the basic principles and theories of transport in biological systems with fundamental bioengineering. It contains real world applications in drug delivery systems, tissue engineering, and artificial organs. Considerable significance is placed on developing a quantitative understanding of the underlying physical, chemical, and biological phenomena. Therefore, many mathematical methods are developed using compartmental approaches. The book is replete with examples and problems.



Service Characteristics Of Biomedical Materials And Implants

Author : Andrew William Batchelor

Publisher : World Scientific

Page : 260 pages

File Size : 47,52 MB

Release : 2004-10-21

Category : Medical

ISBN : 1783260602

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Book Description

A wide variety of materials is being used in biomedical engineering for various functions. This includes a range of ceramics, polymers and metallic materials for implants and medical devices. A major question is how these materials will perform inside the body, which is very sensitive to alien materials. The material must not only survive to perform its intended function but also not initiate any damage to the surrounding tissue or induce a wider health problem. The service characteristics of implanted materials are of vital concern to health treatments that alleviate ageing.This book collates information and provides a concise text on the performance of different materials used in devices and implants. The knowledge presented is critical for a biomedical engineer, especially for the purpose of selecting the right materials. In addition, topics such as allergies and infection, tissue scaffolds, and drug delivery are reviewed.