Author : John A. M. Ramshaw
Publisher : Institute of Physics Publishing
Page : 346 pages
File Size : 33,28 MB
Release : 2019-11-13
Category : Science
ISBN : 9780750320979
Biophysical and Chemical Properties of Collagen: Biomedical Applications provides an introduction to the biophysics and chemistry of collagen and its use as a biomedical material in the rapidly changing fields of biomedical device production, tissue engineering and regenerative medicine. Written by experts in the field, this text will be of interest for researchers as well as lecturers and students.
Author : John A. M. Ramshaw
Publisher :
Page : 0 pages
File Size : 18,24 MB
Release : 2019
Category : Collagen
ISBN : 9780750320962
Collagen has proved to be a safe and effective biomedical material. Clinicians have used collagen-based devices in a wide range of applications with successful patient outcomes. This book gives an understanding of how present devices work, and could be improved, as well as the development of new devices where a knowledge of collagen structure, chemistry and biology is required. The purification of collagen materials and the fabrication of a range of collagen products and their applications are covered within. Current developments include recombinant collagen materials that provide further application opportunities. Written by experts in the field, this text will be of interest for researchers as well as lecturers and students. Part of Biophysical Society Series.
Author : Peter Fratzl
Publisher : Springer Science & Business Media
Page : 516 pages
File Size : 33,66 MB
Release : 2008-05-10
Category : Technology & Engineering
ISBN : 0387739068
Not only does this book provide a comprehensive review of current research advances in collagen structure and mechanics, it also explores this biological macromolecule’s many applications in biomaterials and tissue engineering. Readers gain an understanding of the structure and mechanical behavior of type I collagen and collagen-based tissues in vertebrates across all length scales, from the molecular (nano) to the organ (macro) level.
Author : Harry R. Elden
Publisher :
Page : 680 pages
File Size : 35,66 MB
Release : 1971
Category : Skin
ISBN :
Author : Joseph Raymond Kanagy
Publisher :
Page : 28 pages
File Size : 41,21 MB
Release : 1947
Category : Adhesives
ISBN :
One of the most important industrial proteins is collagen. On treatment with tannins or certain inorganic salts, it is converted into leather. This process is known as tanning. By prolonged heating with water, collagen is changed into glue, which has a large number of commercial applications, such as the making of paper, photographic plates, and adhesives. This Circular gives a general outline of the physical and chemical properties of collagen, and was prepared for the large numbers of chemists employed in industries in which this material or its transition product, glue, is processed.
Author : Richard Maynes
Publisher : Elsevier
Page : 328 pages
File Size : 14,61 MB
Release : 2012-12-02
Category : Science
ISBN : 0323155715
Structure and Function of Collagen Types is a collection of articles that reviews the different types of collagens (Type I to XI). Each article focuses on a particular type of collagen and written by leading investigators in the collagen field. The book begins with a review of the fibril forming collagens (types I, II, and III) and traces the early work on the structure of these collagens to our knowledge of the structure of the collagen genes. This chapter is followed by a detailed description of type IV (basement membrane) collagen. Chapter 3 addresses the biosynthesis and chain assembly of type V collagen. The evidence that type VI collagen is assembled to form tetramers is presented in chapter 4. The subsequent article shows that type VII collagens are assembled to form partially overlapping dimers. Chapter 6 presents the structure of type VIII collagen. Chapters 7, 8, and 9 discuss the structure and characteristics of collagens that are synthesized by cartilaginous tissues and these are designated as type IX, type X, and type XI. The final chapter reviews the recombinant DNA techniques used to investigate collagen structure and the possibility to recognize new collagen types from a cDNA library. Physiologists, cell biologists, and researchers in the field of collagen will find the text very insightful.
Author : Gopalasamudram Ramachandran
Publisher : Springer Science & Business Media
Page : 546 pages
File Size : 40,5 MB
Release : 2013-06-29
Category : Science
ISBN : 1475746024
Collagen is a fascinating protein not only because of its ubiquitous occurrence in multicellular animals, but also because of its unique chemi cal structure. As the predominant constituent in bone, cartilage, skin, tendon, and tooth, it is not surprising that collagen is of interest to anatomists, biochemists, biomedical engineers, cell biologists, dermatolo gists, dental surgeons, leather chemists, orthopedic surgeons, physiologists, physicians, zoologists, and a host of others. This book was planned to provide an up-to-date comprehensive survey of all aspects of biochemistry of collagen. The recent discovery of genetically distinct collagens with tissue specificity has opened a new era in collagen biochemistry, and Karl Piez discusses this in the opening chapter on primary structure. In the next chapter, Ramachandran and Rama krishnan deal with the molecular structure of collagen, placing special emphasis on the conformational aspects of its polypeptide chains. Follow ing the consideration of primary and secondary structure of collagen, the three-dimensional arrangement of collagen molecules in the fibrils is covered by Miller in Chapter 3. Collagen is generally in the insoluble state in the living organism due to the cross-linking of individual molecules, and Tanzer describes the various aspects of this cross-linkage in Chapter 4. The biosynthesis of collagen is discussed in depth by Prockop and his colleagues.
Author : John T. Edsall
Publisher : Academic Press
Page : 716 pages
File Size : 48,96 MB
Release : 2014-05-12
Category : Science
ISBN : 1483270580
Biophysical Chemistry, Volume I: Thermodynamics, Electrostatics, and the Biological Significance of the Properties of Matter focuses on the biological aspects of the properties of matter, putting emphasis on the chemical elements, water and carbon dioxide, complex molecules, and proteins. The publication first elaborates on biochemistry and geochemistry, water and its biological significance, and the problems of protein structure. Discussions focus on the number of peptide chains in the molecule and nature of terminal groups, latent heat of fusion, characteristics of the amino acids derived from proteins, expansion of water in freezing, and the relative abundance of chemical elements in the universe. The text then takes a look at thermodynamics and the application to polar molecules and ionic solutions of electrostatics, including free energy of a charged sphere, image charges, salting-out effect, expressions for the change of fundamental thermodynamic functions, and chemical potentials. The book examines the conductivity of electrolytes, acid-base equilibria, and polybasic acids, bases, and ampholytes, including proteins. Topics include ionization of cysteine, isoelectric points of polyvalent ampholytes, hemoglobin, nature of acids and bases, measurement of conductivity, electrolytes as conductors, and the moving boundary method of determining transference numbers. The manuscript is a dependable reference for chemists and researchers interested in thermodynamics, electrostatics, and the biological value of the properties of matter.
Author : Eugene J. Kucharz
Publisher : Springer Science & Business Media
Page : 429 pages
File Size : 22,61 MB
Release : 2012-12-06
Category : Science
ISBN : 3642761976
This book describes every manner in which collagen is involved in normal anddisease-altered states of the various organs and systems. In the first part of the book the biochemical aspects of collagens are reviewed, including their structure, heterogeneity, syntheses, and degradation. The main part focuses on the involvement of collagen in bone, cartilage, tendon, muscle, heart, vessels, lungs, liver, skin, eye, ear, teeth, periodontal tissues, kidneys and reproductive, hemopoietic,and nervous systems. The influence of radiation and nutrition on collagen, the role of collagen in neoplasms, the hormonal control of its metabolism, immunobiology and the pharmacology of collagen are also described. The most important feature of the book is the comprehensive review of the medical aspects of collagen, from those known in detail to those only hypothesized including hereditary disorders affecting collagen and so-called collagen diseases. Each chapter reviewsknown or possible mechanisms of collagen involvement and changes in indices of collagen which can be measured in clinical practice to monitor these phenomena. The fact that collagen is involved into the pathophysiology of almost all organs and body systems means that physicians in almost all branches of medicine will find this book of great interest.
Author : Morten Karsdal
Publisher : Elsevier
Page : 586 pages
File Size : 34,50 MB
Release : 2023-11-07
Category : Science
ISBN : 0443156182
Biochemistry of Collagens, Laminins, and Elastin: Structure, Function and Biomarkers, Third Edition provides current data on key structural proteins (collagens, laminins, and elastin), reviews on how these molecules affect pathologies, and information on how selected modifications of these proteins can result in altered signaling properties of the original extracellular matrix (ECM). Further, it discusses the novel concept that an increasing number of components of the extracellular matrix harbor cryptic signaling functions with ties to endocrine function, and how this knowledge may be used to modulate various pathologies, including fibrotic disease. This new edition has been expanded and revised to incorporate recent research advances. Several new chapters explore a range of chronic diseases in which the ECM and collagens, laminin and elastin are central players in disease modulation, including new chapters on lung, skin and intestinal disease, as well as cancers. The new edition also considers emerging analytical technologies that can detect biomarkers of ECM degradation, with discussion of protein quantification and detecting aging of collagens. Provides an updated, comprehensive discussion of collagen and related structural proteins Contains insights into biochemical interactions and changes to structural composition of proteins in disease states Proves the importance of proteins for collagen assembly, function and durability Examines details on how collagens play a key role in a range of chronic diseases Offers approaches for protein quantification and detection of collagen aging
