Biophysical and Chemical Properties of Collagen: Biomedical Applications: Biomedical Applications


Book Description

Biophysical and Chemical Properties of Collagen: Biomedical Applications provides an introduction to the biophysics and chemistry of collagen and its use as a biomedical material in the rapidly changing fields of biomedical device production, tissue engineering and regenerative medicine. Written by experts in the field, this text will be of interest for researchers as well as lecturers and students.




Biophysical Chemistry


Book Description

Biophysical chemistry is one of the most interesting interdisciplinary research fields. Some of its different subjects have been intensively studied for decades. Now the field attracts not only scientists from chemistry, physics, and biology backgrounds but also those from medicine, pharmacy, and other sciences. We aimed to start this version of the book Biophysical Chemistry from advanced principles, as we include some of the most advanced subject matter, such as advanced topics in catalysis applications (first section) and therapeutic applications (second section). This led us to limit our selection to only chapters with high standards, therefore there are only six chapters, divided into two sections. We have assumed that the interested readers are familiar with the fundamentals of some advanced topics in mathematics such as integration, differentiation, and calculus and have some knowledge of organic and physical chemistry, biology, and pharmacy. We hope that the book will be valuable to graduate and postdoctoral students with the requisite background, and by some advanced researchers active in chemistry, biology, biochemistry, medicine, pharmacy, and other sciences.







Research Awards Index


Book Description




Soft Matter for Biomedical Applications


Book Description

Dynamic soft materials that have the ability to expand and contract, change stiffness, self-heal or dissolve in response to environmental changes, are of great interest in applications ranging from biosensing and drug delivery to soft robotics and tissue engineering. This book covers the state-of-the-art and current trends in the very active and exciting field of bioinspired soft matter, its fundamentals and comprehension from the structural-property point of view, as well as materials and cutting-edge technologies that enable their design, fabrication, advanced characterization and underpin their biomedical applications. The book contents are supported by illustrated examples, schemes, and figures, offering a comprehensive and thorough overview of key aspects of soft matter. The book will provide a trusted resource for undergraduate and graduate students and will extensively benefit researchers and professionals working across the fields of chemistry, biochemistry, polymer chemistry, materials science and engineering, nanosciences, nanotechnologies, nanomedicine, biomedical engineering and medical sciences.




Biomedical Hydrogels


Book Description

Hydrogels are very important for biomedical applications because they can be chemically manipulated to alter and control the hydrogel's interaction with cells and tissues. Their flexibility and high water content is similar to that of natural tissue, making them extremely suitable for biomaterials applications. Biomedical hydrogels explores the diverse range and use of hydrogels, focusing on processing methods and novel applications in the field of implants and prostheses. Part one of this book concentrates on the processing of hydrogels, covering hydrogel swelling behaviour, superabsorbent cellulose-based hydrogels and regulation of novel hydrogel products, as well as chapters focusing on the structure and properties of hydrogels and different fabrication technologies. Part two covers existing and novel applications of hydrogels, including chapters on spinal disc and cartilage replacement implants, hydrogels for ophthalmic prostheses and hydrogels for wound healing applications. The role of hydrogels in imaging implants in situ is also discussed. With its distinguished editor and international team of contributors, Biomedical hydrogels is an excellent reference for biomedical research scientists and engineers in industry and academia, as well as others involved in research in this area, such as research clinicians. - Examines the diverse range and use of hydrogels, focusing on processing methods and novel applications - Comprehensive book explores the structure and properties of hydrogels and different fabrication technologies - Covers important areas such as processing of hydrogels, covering hydrogel swelling behaviour, superabsorbent cellulose-based hydrogels and regulation of novel hydrogel products




Biomedical Polymers


Book Description

This book presents a comprehensive review on the various processing and post-processing methodologies for biodegradable polymers. Written by professionals with hands-on experience on polymer processing, this book provides first-hand knowledge of all contemporary processing techniques. The current status and future challenges in the field are described, as well as a framework for designing novel devices for desired applications.




Materials Development and Processing for Biomedical Applications


Book Description

Materials Development and Processing for Biomedical Applications focuses on various methods of manufacturing, surface modifications, and advancements in biomedical applications. This book examines in detail about five different aspects including, materials properties, development, processing, surface coatings, future perspectives and fabrication of advanced biomedical devices. Fundamental aspects are discussed to better understand the processing of various biomedical materials such as metals, ceramics, polymers, composites, etc. A wide range of surface treatments are covered in this book that will be helpful for the readers to understand the importance of surface treatments and their future perspectives. Additional Features Include: Examines various properties of biomedical materials at the beginning in several chapters which will enrich the fundamental knowledge of the readers. Discusses advancements in various fields of biomedical applications. Provides a glimpse of characterization techniques for the evaluation of material properties. Addresses biocompatibility, biocorrosion, and tribocorrosion. This book explores new and novel strategies for the development of materials and their biomedical applications. It will serve as a comprehensive resource for both students and scientists working in materials and biomedical sciences.




Inorganic Biomaterials


Book Description

This book provides a practical guide to the use and applications of inorganic biomaterials. It begins by introducing the concept of inorganic biomaterials, which includes bioceramics and bioglass. This concept is further extended to hybrid biomaterials consisting of inorganic and organic materials to mimic natural biomaterials. The book goes on to provide the reader with information on biocompatibility, bioactivity and bioresorbability. The concept of the latter is important because of the increasing role resorbable biomaterials are playing in implant applications. The book also introduces a new concept on mechanical compatibility - 'mechacompatibility'. Almost all implant biomaterials employed to date, such as metal and ceramic implants, do not meet this biological requirement as they have far higher modulus than any biomaterials in the body. The practical techniques that are used in the characterization of biomaterials, including chemical, physical, biological, microscopy and mechanical characterization are described. Some specialised techniques are also introduced such as Synchrotron Micro-Computed Tomography (u-CT) and Magnetic Resonance Imaging (MRI). The reader is given important information on new biomaterials development for orthopaedic and other areas, including controlled release technology, hydroxyapatite and hybrid bioresorbable materials. Finally the book provides a guide to regulatory considerations, an area which is often overlooked, but is an important part of R&D and manufacturing of medical materials and devices.




Characterization of Biomaterials


Book Description

The physicochemical properties of biomaterials exert a major influence over their interaction with cells and subsequently play an important role on the materials' in vivo performance . Physical characteristics involve internal microstructural features, shape and size of particles, porosity, density, and surface area. Characterization in terms of the chemistry involves determination of the chemical composition and distribution of the elements within the biomaterial. The last decade has seen several innovations in the armory of tools to image and analyze materials, as well as advancement in the collection and processing of those results. In this chapter, the most commonly used methods, which are available for the microstructural characterization of biomaterials, are explained with suitable examples. This chapter starts with microstructural characterization using different types of microscopic techniques including optical and electron microscopy. These techniques can provide information from atomic-scale to microscale to macroscale information. Specific examples are also used for specialized microscopic techniques such as scanning probe microscopy and atomic force microscopy. Some discussions were also used in -related surface characterization using microscopic techniques. Followed by microscopic techniques, phase analysis techniques are discussed based on X-ray diffraction. Short discussion is also placed on infrared (IR)-based spectroscopic characterization for chemical analysis. Further discussion on IR spectroscopy can be found in for surface analysis. The last part of this chapter deals with size, shape, porosity, surface area and surface energy characterization. Particle size analysis by dynamic light scattering (DLS) is discussed in detail followed by IR spectroscopic analysis. Contact angle measurement for surface energy, mercury intrusion porosimetry for analysis of pore structures and gas adsorption measurements for surface area analysis are presented in detail with relevant examples. Throughout this chapter, specific discussions are focused on examples based on applications as well as advantages, disadvantages, and challenges.