Biophysical and Structural Aspects of Bioenergetics


Book Description

Bioenergetics is a term used to describe the events of primary energy transduction in biology. The field has seen tremendous advances in recent years thanks to developments in the biophysical and computational techniques used to solve the three-dimensional structures of the membrane-bound proteins, which often act as catalysts in these reactions. This has enabled researchers to bring, otherwise static, structures to life and decipher the dynamic function of these intriguing systems. Biophysical and Structural Aspects of Bioenergetics brings together contributions from internationally respected experts, all of whom helped shape and develop the field of bioenergetics. It provides a representative snapshot of the very latest key developments in this multidisciplinary subject, with an emphasis on molecular structure, and how this changes during the bioenergetic function. Offering a comprehensive overview of the current state of the art, and complete with extensive citations in each chapter, this book is the ideal reference for both biochemists and biophysicists studying this fascinating topic.




Comprehensive Biophysics


Book Description

Biophysics is a rapidly-evolving interdisciplinary science that applies theories and methods of the physical sciences to questions of biology. Biophysics encompasses many disciplines, including physics, chemistry, mathematics, biology, biochemistry, medicine, pharmacology, physiology, and neuroscience, and it is essential that scientists working in these varied fields are able to understand each other's research. Comprehensive Biophysics, Nine Volume Set will help bridge that communication gap. Written by a team of researchers at the forefront of their respective fields, under the guidance of Chief Editor Edward Egelman, Comprehensive Biophysics, Nine Volume Set provides definitive introductions to a broad array of topics, uniting different areas of biophysics research - from the physical techniques for studying macromolecular structure to protein folding, muscle and molecular motors, cell biophysics, bioenergetics and more. The result is this comprehensive scientific resource - a valuable tool both for helping researchers come to grips quickly with material from related biophysics fields outside their areas of expertise, and for reinforcing their existing knowledge. Biophysical research today encompasses many areas of biology. These studies do not necessarily share a unique identifying factor. This work unites the different areas of research and allows users, regardless of their background, to navigate through the most essential concepts with ease, saving them time and vastly improving their understanding The field of biophysics counts several journals that are directly and indirectly concerned with the field. There is no reference work that encompasses the entire field and unites the different areas of research through deep foundational reviews. Comprehensive Biophysics fills this vacuum, being a definitive work on biophysics. It will help users apply context to the diverse journal literature offering, and aid them in identifying areas for further research Chief Editor Edward Egelman (E-I-C, Biophysical Journal) has assembled an impressive, world-class team of Volume Editors and Contributing Authors. Each chapter has been painstakingly reviewed and checked for consistent high quality. The result is an authoritative overview which ties the literature together and provides the user with a reliable background information and citation resource




Principles of Bioenergetics


Book Description

Principles of Bioenergetics summarizes one of the quickly growing branches of modern biochemistry. Bioenergetics concerns energy transductions occurring in living systems and this book pays special attention to molecular mechanisms of these processes. The main subject of the book is the "energy coupling membrane" which refers to inner membranes of intracellular organelles, for example, mitochondria and chloroplasts. Cellular cytoplasmic membranes where respiratory and photosynthetic energy transducers, as well as ion-transporting ATP-synthases (ATPases) are also part of this membrane. Significant attention is paid to the alternative function of mitochondria as generators of reactive oxygen species (ROS) that mediate programmed death of cells (apoptosis and necrosis) and organisms (phenoptosis). The latter process is considered as a key mechanism of aging which may be suppressed by mitochondria-targeted antioxidants.




The Purple Phototrophic Bacteria


Book Description

Here is a comprehensive survey of all aspects of these fascinating bacteria, metabolically the most versatile organisms on Earth. It compiles 48 chapters written by leading experts, who highlight the huge progress made in studies of these bacteria since 1995.




Bioenergetics


Book Description

The original authors-see later for detail




Mechanisms of Primary Energy Transduction in Biology


Book Description

An essential resource for biochemists, biophysicists and chemical biologists, providing a complete understanding of the molecular machines of bioenergetics.







Biophysical Approaches Determining Ligand Binding to Biomolecular Targets


Book Description

The binding of small ligands to biological molecules is central to most aspects of biological function. The past twenty years has seen the development of an increasing armoury of biophysical methods that not only detect such binding, but also provide varying degrees of information about the kinetics, thermodynamics and structural aspects of the process. These methods have received increasing attention with the growth in more rational approaches to drug discovery and design. This book reviews the latest advances in the application of biophysics to the study of ligand binding. It provides a complete overview of current techniques to identify ligands, characterise their binding sites and understand their binding mechanisms. Particular emphasis is given to the combined use of different techniques and their relative strengths and weaknesses. Consistency in the way each technique is described makes it easy for readers to select the most suitable protocol for their research. The introduction explains why some techniques are more suitable than others and emphasizes the possible synergies between them. The following chapters, all written by a specialist in the particular technique, focus on each method individually. The book finishes by describing how several complimentary techniques can be used together for maximum effectiveness. This book is suitable for biomolecular scientists at graduate or post-doctoral level in academia and industry. Biologists and chemists will also find it a useful introduction to the techniques available.




Energy Transduction in Biological Membranes


Book Description

Energy Transduction in Biological Membranes was primarily designed for graduate courses in bioenergetics. Not only does it discuss basic principles and concepts central to modern membrane biochemistry, biophysics and molecular biology, but also (1) the components and pathways for electron transport and hydrogen ion translocation, and (2) the utilization of electrochemical ion gradients. The book is unique in presenting a comparative treatment of respiratory and photosynthetic energy transduction, and in using protein sequence data coupled with physical concepts to discuss the mechanisms of energy transducing proteins.




Bioenergetics


Book Description

Bioenergetics deals with the very first energy transformation steps performed by living cells. Increased dissipation is the primary effect of processing external energy packages. Enzyme-supported charge separation is the minor but essential outcome for maintaining life. This book explores the usefulness of dissecting the entropy production of enzymes involved in cellular defenses, fermentation, respiration, and photosynthesis, assuming that tightly regulated dissipation is the hallmark of life. Researchers, educators, and students of life sciences can find in this text many examples of how we can use the interdisciplinary approach to study cells' virtuoso ability to connect the microscopic to the macroscopic world. Each chapter is a self-contained unit with a glossary and selected references for further reading.