Bioprobes


Book Description

This new edition provides the most advanced research using bioprobes on the chemical control of 1) cell cycle and differentiation, 2) epigenetics, 3) apoptosis and autophagy, and 4) immune response. The “bioprobe”, first proposed in the first edition, has become an indispensable tool for chemical biology and has substantially assisted in the investigation of complex biochemical processes of cells. New areas of investigation such as stem cell research, epigenetic research, and autophagy research have rapidly advanced in the past 10 years. Including these new findings, this second edition supplies up-to-date information on the biochemical tools called bioprobes. Data on each bioprobe, such as chemical structure, origin, function, and references, are presented as one item in this volume. Readers will easily find useful information and will be able to determine the appropriate bioprobes to investigate cell functions. The information on bioprobes and their use in research makes this book a valuable source for researchers in diverse fields. Not only scientists in academia but also in the pharmaceutical industries will discover the most important information about small molecules useful for drug discovery.




Bioprobes


Book Description

Rapid advances in the study of the molecular basis of mammalian cell proliferation, differentiation, and apoptosis have made it possible to develop new screening systems for isolating from microbial metabolites specific inhibitors of mammalian cell functions. "Bioprobes" is the term used to describe these inhibitors, which are extremely useful agents in investigating the molecular and chemical regulation of eukaryotic cell function and apoptosis. Another area where bioprobes are playing an important role is research into immune cell function. This book is the first to present the groundbreaking applications of bioprobes as tools for biochemical research. A large appendix contains the chemical structure, origin, function, key references, and other essential data for more than 80 important bioprobes. The information for each bioprobe is shown in a two-page display, in an easy-to-use format for identifying specific bioprobes for investigation of cell function.




Biosensors


Book Description

Biosensors are analytical devices that combine a biologically sensitive element with a physical or chemical transducer to selectively and quantitatively detect the presence of specific compounds. Balancing basics, principles, and case studies, Biosensors: Microelectrochemical Devices covers the theory and applications of one class of biosensor-microelectrochemical devices. The book clearly explains microelectronic techniques used to produce these cheap, fast reacting, and disposable sensors with the aid of helpful diagrams and tables. Researchers and postgraduates active in the field of chemical sensors, analytical chemistry, or microelectronics will find this an invaluable reference.




The Rare Earth Elements


Book Description

Lanthanides are of great importance for the electronic industries, this new book (from the EIBC Book Series) provides a comprehensive coverage of the basic chemistry, particularly inorganic chemistry, of the lanthanoid elements, those having a 4f shell of electrons. A chapter is describing the similarity of the Group 3 elements, Sc, Y, La, the group from which the lanthanoids originate and the group 13 elements, particularly aluminum, having similar properties. Inclusion of the group 3 and 13 elements demonstrates how the lanthanoid elements relate to other, more common, elements in the Periodic Table. Beginning chapters describe the occurrence and mineralogy of the elements, with a focus on structural features observed in compounds described in later chapters. The majority of the chapters is organized by the oxidation state of the elements, Ln(0), Ln(II), Ln(III), and Ln(IV). Within this organization the chapters are further distinguished by type of compound, inorganic (oxides and hydroxides, aqueous speciation, halides, alkoxides, amides and thiolates, and chelates) and organometallic. Concluding chapters deal with diverse and critically important applications of the lanthanoids in electronic and magnetic materials, and medical imaging.




Bioorganometallic Chemistry


Book Description

An up-to-date reference reflecting the significant advances and important breakthroughs made in this emerging discipline over the last decade. As such, the book provides an overview of the latest developments and future trends in the field, focusing on such applications as the development of potentially active organometallic drugs against incurable diseases, as well as in such areas as catalysis, energy, analytical chemistry, and imaging. The renowned editor, who established the term "bioorganometallics", and his international team of experts have put together a valuable resource for researchers in organometallic, inorganic, medicinal, and biochemistry.




Silicon Nano-biotechnology


Book Description

This book reviews the latest advances in the development of silicon nano-biotechnology for biological and biomedical applications, which include biosensing, bioimaging, and cancer therapy. In this book, newly developed silicon nano-biotechnology and its biomedical applications are systematically introduced. For instance, fluorescent silicon nanoparticles, serving as novel high-performance biological nanoprobes, are superbly suited to real-time and long-term bioimaging. Silicon nanowire-based sensing platform is especially capable of sensitive, specific, and multiplexed detection of various biological species. Silicon-based nanocarriers with ultra-high drug-loading capacity are highly efficacious for in vitro and in vivo cancer therapies. This book is intended for readers who are interested in the design of functional silicon nanostructures and their biological and biomedical applications. It uses silicon nanoparticles and silicon nanowires as models and discusses topics ranging from their synthesis to their biological applications, the goal being to highlight these exciting achievements as starting points in the field of silicon nano-biotechnology. Yao He is a Professor at Institute of Functional Nano&Soft Materials (FUNSOM), Soochow University, China. Yuanyuan Su is an Associate Professor at Institute of Functional Nano&Soft Materials (FUNSOM), Soochow University, China.




Bioorganometallics


Book Description

This first comprehensive book to cover the expanding field of bioorganometallics represents the perfect starting point for beginners but also an excellent source of high quality information for experts in the field. Edited by a pioneer in the field with an excellent standing within the community, this book begins with the history of bioorganometallics, before going on to cover pharmaceuticals, bioorganometallic chemistry and radiopharmaceuticals. A must for bioinorganic chemists, the pharmaceutical industry, chemists working in organometallics and biochemists.




Luminescent Agents—Advances in Research and Application: 2012 Edition


Book Description

Luminescent Agents—Advances in Research and Application: 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Luminescent Agents in a concise format. The editors have built Luminescent Agents—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Luminescent Agents in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Luminescent Agents—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.




Inorganic and Organometallic Transition Metal Complexes with Biological Molecules and Living Cells


Book Description

Inorganic and Organometallic Transition Metal Complexes with Biological Molecules and Living Cells provides a complete overview of this important research area that is perfect for both newcomers and expert researchers in the field. Through concise chapters written and edited by esteemed experts, this book brings together a comprehensive treatment of the area previously only available through scattered, lengthy review articles in the literature. Advanced topics of research are covered, with particular focus on recent advances in the biological applications of transition metal complexes, including inorganic medicine, enzyme inhibitors, antiparasital agents, and biological imaging reagents. - Geared toward researchers and students who seek an introductory overview of the field, as well as researchers working in advanced areas - Focuses on the interactions of inorganic and organometallic transition metal complexes with biological molecules and live cells - Foscuses on the fundamentals and their potential therapeutic and diagnostic applications - Covers recent biological applications of transition metal complexes, such as anticancer drugs, enzyme inhibitors, bioconjugation agents, chemical biology tools, and bioimaging reagents




Recognition of Carbohydrates in Biological Systems, Part A: General Procedures


Book Description

Recognition of carbohydrates in biological systems has been gaining more and more attention in recent years. Although methodology for studying recognition has been developing, there is no volume that covers the wide area of methodology of carbohydrate recognition. This volume, Recognition of Carbohydrates in Biological Systems, Part A: General Procedures, and its companion, Volume 363, present state-of-the-art methodologies, as well as the most recent biological observations in this area. Covers the isolation/synthesis of substances used in studying interactions involving carbohydrates Discussed the methodology for measuring such interactions Biological roles for such interactions are also covered