Biosensors and Molecular Imprinting


Book Description

This book is a printed edition of the Special Issue "Biosensors and Molecular Imprinting" that was published in Sensors




Molecularly Imprinted Sensors


Book Description

Molecular imprinting is a rapidly growing field with wide-ranging applications, especially in the area of sensor development, where the process leads to improved sensitivity, reliability, stability, and reproducibility in sensing materials. Molecularly Imprinted Sensors in Analytical Chemistry addresses the most recent advances and challenges relating to molecularly imprinted polymer sensors, and is the only book to compile this information in a single source. From fundamentals to applications, this material will be valuable to researchers working in sensing technologies for pharmaceutical separation and chemical analysis, environmental monitoring and protection, defense and security, and healthcare. Provides a systematic introduction to the different types of MIP-based sensors and reviews the basic principles behind each type of sensor Includes state-of-the-art methodology supported by comparisons and discussions from leading experts in the field Covers all types of sensing modes (optical, electrochemical, thermal, acoustic, etc.), materials and platforms Appeals to a multidisciplinary audience of scientists and graduate students in a wide variety of fields, including chemistry, biology, biomedical science and engineering, and materials science and engineering




Handbook of Molecular Imprinting


Book Description

Molecular imprinting focuses on the fabrication of an artificial receptor with perfect molecular recognition abilities. It has attracted a great deal of scientific attention because of the enormous opportunities it opens in the fields of separation, catalysis, and analysis. The advantages of the molecular imprinting enable to target a wide class of substances ranging from small molecules to big conglomerates, such as proteins or even cells. In recent years, sensor applications based on molecular imprinting have started to attract greater attention because of the easy creation of robust receptor sites with high specificity and sensitivity toward a target compound. A collection of contributions from distinguised experts, Handbook of Molecular Imprinting: Advanced Sensor Applications provides a comprehensive overview on the specific challenges of molecular imprinting in sensor applications. It covers various molecular imprinting approaches. As a result, a perspective of future device ensembles for sensing is acquired. The text lays particular emphasis on fundamental aspects as well as novel ideas in the context of sensor applications. It also highlights the operation principles of various sensor transducers that are generally employed in combination with molecular imprinting recognition elements.




Applications of Nanomaterials in Agriculture, Food Science, and Medicine


Book Description

The uses of nanotechnologies continue to rise exponentially. Due to their multifaceted nature, nanomaterials have a vast amount of potential uses in various scientific professions. Professionals in sectors including agriculture, nutrition, and healthcare are discovering the numerous benefits that nanomaterials carry when applied to traditional practices. In order to understand the dynamic properties of nanomaterials and how to utilize them in specific fields, significant research is required. Applications of Nanomaterials in Agriculture, Food Science, and Medicine is an essential reference source that discusses the emerging development of nanotechnology in various sectors of the scientific community as well as the current benefits and future uses. Industries that the book covers include energy storage and renewable energy, environmental science and wastewater treatment, food and agriculture, and medicine and bioinformatics. This book is ideally designed for researchers, engineers, practitioners, industrialists, educators, strategists, policymakers, scientists, and students seeking coverage on the strategic role of nanomaterials in these imperative fields.




Molecular Imprinting for Nanosensors and Other Sensing Applications


Book Description

Molecular Imprinting for Nanosensors and Other Sensing Applications provides fundamental knowledge on molecular imprinting, including types, preparation methods, properties and characterization techniques. The book also covers the state-of-the-art technological developments of sensors that incorporate with microfluidic systems, lab-on-a-chip-tools, and other techniques. Sections discuss the integration of molecularly imprinted polymers with current top-notch tools and platforms that facilitate their potential applications in the realms of medicine, pharmaceuticals and environmental monitoring. Topics of note include molecularly imprinted polymer-based sensor models, their functionalization methodologies, prominent characteristics, and their characterization tools. Covers, in an in-depth manner, molecular imprinting as it relates to nanosensors Provides an appropriate resource on the various applications of imprinted sensors, such as their use in the environment, medicine and food industry Includes future outlooks and expectations for sensor technology




Label-Free Biosensing


Book Description

This volume summarizes the state-of-the-art technologies, key advances and future trends in the field of label-free biosensing. It provides detailed insights into the different types of solid-state, label-free biosensors, their underlying transducer principles, advanced materials utilized, device-fabrication techniques and various applications. The book offers graduate students, academic researchers, and industry professionals a comprehensive source of information on all facets of label-free biosensing and the future trends in this flourishing field. Highlights of the subjects covered include label-free biosensing with: · semiconductor field-effect devices such as nanomaterial-modified capacitive electrolyte-insulator-semiconductor structures, silicon nanowire transistors, III-nitride semiconductor devices and light-addressable potentiometric sensors · impedimetric biosensors using planar and 3D electrodes · nanocavity and solid-state nanopore devices · carbon nanotube and graphene/graphene oxide biosensors · electrochemical biosensors using molecularly imprinted polymers · biomimetic sensors based on acoustic signal transduction · enzyme logic systems and digital biosensors based on the biocomputing concept · heat-transfer as a novel transducer principle · ultrasensitive surface plasmon resonance biosensors · magnetic biosensors and magnetic imaging devices




Immunosensors


Book Description

Immunosensors are widely used and are particularly important for fast diagnosis of diseases in remote environments as well as point-of-care devices. In this book, expert scientists are covering a selection of high quality representative examples from the past five years explaining how this area has developed. It is a compilation of recent advances in several areas of immunosensors for multiple target analysis using laboratory based or point-of-care set-up, for example graphene-, ISFET- and nanostructure-based immunosensors, electrochemical magneto immunosensors and nanoimprinted immunosensors. Filling a gap in the literature, it showcases the multidisciplinary, innovative developments in this highly important area and provides pointers towards commercialisation. Delivering a single, comprehensive work, it appeals to graduate students and professional researchers across academia and industry.




Tools, Techniques and Protocols for Monitoring Environmental Contaminants


Book Description

Tools, Techniques and Protocols for Monitoring Environmental Contaminants describes information on the strategic integration of available monitoring methods with molecular techniques, with a focus on omics (DNA, RNA and protein based) and molecular imprinted polymer and nanomaterial based advanced biosensors for environmental applications. It discusses the most commonly practiced analytic techniques, such as HPLC, MS, GCMS and traditional biosensors, giving an overview of the benefits of advanced biosensors over commonly practiced methods in the rapid and reliable assessment of environmental contaminants. As environmental contaminants have become one of the serious concerns in terms of their rapid growth and monitoring in the environment, which is often limited due to costly and laborious methods, this book provides a comprehensive update on their removal, the challenges they create for environmental regulatory agencies, and their diverse effects on terrestrial and aquatic environments. Provides methods for assessing and monitoring environmental contaminants Includes recent advancement in molecular techniques Outlines rapid environmental monitoring methods Explains the use of biosensors for environmental monitoring Reviews monitoring methods beyond conventional analytic techniques




Molecular Imprinting Technology Towards the Development of a Novel Biosensor


Book Description

Current advances in molecular imprinting has many drawbacks such as the lack of specificity, this is the inability to selectively detect one single species of biomolecule. In addition, it is very difficult to produce a device that accounts with high sensitivity to detect relevant biomolecules and generate reproducible data from complex samples. The present project aims to offer an alternative by developing a technique to synthesize a polymeric matrix with molecularly imprinted cavities that excludes non-targeted species and binds to the targeted molecule, this synthetic platform in combination with proven efficient surface plasmon resonance technology achieve high sensitivity, for real time monitoring of molecular binding. Polyacrylamide is a hydrophilic and biocompatible synthetic polymer used in industry and in the lab. It is used in chromatography, electrophoresis, and recently it has been used in molecular imprinting. However conventional techniques for molecular imprinting using acrylamide as the functional monomer are not yet robust enough due to the high swelling ratio in the presence of water. In the present study, molecularly imprinted polyacrylamide was produced in nano-thin films on top of the gold surface of a surface plasmon resonance sensor. The model template used in this study was lysozyme and bovine serum albumin because they are relatively big and complex proteins that easily solubilize in water. The system was evaluated by comparing signals when exposing the imprinted polyacrylamide to a solution containing lysozyme. Uv-Vis spectrophotometry, scanning electron microscopy (SEM), matrix assisted laser desorption ionization coupled with time of flying mass spectrometry (MALDI-TOF MS), and surface plasmon resonance (SPR) were used to characterize the novel biosensor. The results obtained from this project showed that it is possible to prepare a molecularly imprinted system with high sensitivity and selectivity that is stable and offers reproducibility in the detection of proteins.




Biosensors for Virus Detection


Book Description

Developments and applications of biosensor platforms for analysis of viral infections including Coronavirus, HIV, Hepatitis, Ebola, Zika, Norovirus, Influenza, SARS etc. Embraces properties, fabrication, and recent research regarding optical, electrochemical, piezoelectric, fluorescence, thermal, magnetic and micromechanical sensor families.