Biosensors for Security and Bioterrorism Applications


Book Description

This book offers comprehensive coverage of biomarker/biosensor interactions for the rapid detection of weapons of bioterrorism, as well as current research trends and future developments and applications. It will be useful to researchers in this field who are interested in new developments in the early detection of such. The authors have collected very valuable and, in some aspects indispensable experience in the area i.e. in the development and application of portable biosensors for the detection of potential hazards. Most efforts are centered on the development of immunochemical assays including flow-lateral systems and engineered antibodies and their fragments. In addition, new approaches to the detection of enzyme inhibitors, direct enzymatic and microbial detection of metabolites and nutrients are elaborated. Some realized prototypes and concept devices applicable for the further use as a basis for the cooperation programs are also discussed.There is a particular focus on electrochemical and optical detection systems,including those employing carbon nanotubes, quantum dots and metalnanoparticles. The authors are well-known scientists and most of them are editors of respected international scientific journals. Although recently developed biosensors utilize known principles, the biosensing devices described can significantly shorten the time required for successful detection and enhance efforts in more time-consuming directions, e.g. remote sensing systems and validation in real-sample analysis.The authors describe advances in all stages of biosensor development: theselection of biochemical components, their use in biosensor assembly, detection principles and improvements and applications for real sample assays.




Portable Chemical Sensors


Book Description

Biosensors are making a large impact in environmental, food, biomedical, and other applications. In comparison to standard analytical detection methods, such as minimal sample preparation and handling, they offer advantages including real time detection, rapid detection of the analytes of concern, use of non-skilled personnel, and portability. The aim of this book is to focus on research related to the rapid detection of agents and weapons of bioterrorism and provide a comprehensive review of the research topics most pertinent to advancing devices applicable to the rapid real-time detection of toxicants such as microbes, pathogens, toxins, or nerve gases. The ongoing war on terrorism and the rising security concerns are driving the need for newer faster biosensors against bio-warfare agents for both military and civil defence applications. The volume brings together contributions from the most eminent international researchers in the field, covering various aspects of work not so far published in any scientific journal and often going beyond the “state of art “ . Readers of these review articles will learn new technological schemes that can lead to the construction of devices that will minimize the risk of bio-terrorism.




Metal Oxides for Biomedical and Biosensor Applications


Book Description

Metal Oxides for Biomedical and Biosensor Applications gives an in-depth overview of the emerging research in the biomedical and biosensing applications of metal oxides, including optimization of their surface and bulk properties. Sections cover biomedical applications of metal oxides for use in cell cultures, antibacterial and antimicrobial treatments, dental applications, drug delivery, cancer therapy, immunotherapy, photothermal therapy, tissue engineering, and metal oxide-based biosensor development. As advanced and biofunctionalized nano/micro structured metal oxides are finding applications in microfluidics, optical sensors, electrochemical sensors, DNA-based biosensing, imaging, diagnosis and analysis, this book provides a comprehensive update on the topic. Additional sections cover research challenges, technology limitations, and future trends in metal oxides and their composites regarding their usage in biomedical applications. - Includes an overview of the important applications of metal oxides for biomedical and biosensing technologies - Addresses the relationship between material properties, such as structure, morphology, composition and performance - Reviews the design and fabrication strategies of metal oxides for use in medical and biosensing applications




Biosensors in Food Safety and Quality


Book Description

Biosensors in food safety and quality have become indispensable in today’s world due to the requirement of food safety and security for human health and nutrition. This book covers various types of sensors and biosensors that can be used for food safety and food quality monitoring, but these are not limited to conventional sensors, such as temperature sensors, optical sensors, electrochemical sensors, calorimetric sensors, and pH sensors. The chapters are framed in a way that readers can experience the novel fabrication procedures of some advanced sensors, including lab-on-a-chip biosensors, IoT-based sensors, microcontroller-based sensors, and so on, particularly for fruits and vegetables, fermented products, plantation products, dairy-based products, heavy metal analysis in water, meat, fish, etc. Its simplistic presentation and pedagogical writing provide the necessary thrust and adequate information for beginners, scientists, and researchers. The book offers comprehensive coverage of the most essential topics, which include the following: Fundamentals of biosensors Overview of food safety and quality analysis Major toxicants of food and water Fabrication techniques of biosensors applicable for different segments of the food industry This book serves as a reference for scientific investigators who work on the assurance of food safety and security using biosensing principles as well as researchers developing biosensors for food analysis. It may also be used as a textbook for graduate-level courses in bioelectronics.




Biosensors and Molecular Imprinting


Book Description

This book is a printed edition of the Special Issue "Biosensors and Molecular Imprinting" that was published in Sensors




Biosensors


Book Description

Biosensors: Fundamentals, Emerging Technologies, and Applications provides insight into the sensing applications of different types of biosensors relating to environmental pollutants, microbiological analysis, and healthcare. It describes state-of-the-art research in biosensors, point of care testing, potential applications, as well as future prospects for biosensors. This book: Presents the essentials that readers need to know to make full use of biosensor technology Discusses recent perspectives on optical and electrochemical biosensors Details biosensor types for medical applications Teaches how to use enzymes for biological recognition in biomarker assays Proposes innovations in wearable and smart biosensors This book is aimed at advanced students, researchers, and academics across a broad interdisciplinary field including biochemical, pharmaceutical, and environmental engineering as well as materials science, analytical chemistry, and biosciences.




Recognition Receptors in Biosensors


Book Description

Recognition receptors play a key role in the successful implementation of chemical and biosensors. Molecular recognition refers to non-covalent speci?c binding between molecules, one of which is typically a macromolecule or a molecular assembly, and the other is the target molecule (ligand or analyte). Biomolecular recognition is typically driven by many weak interactions such as hydrogen bo- ing, metal coordination, hydrophobic forces, van der Waals forces, pi-pi interactions and electrostatic interaction (due to permanent charges, dipoles, and quadrupoles) the polarization of charge distributions by the interaction partner leading to ind- tion and dispersion forces, and Pauli-exclusion-principle-derived inter-atomic repulsion, and a strong, “attractive” force arising largely from the entropy of the solvent and termed the hydrophobic effect. In recent years, there has been much progress in understanding the forces that drive the formation of such complexes, and how these forces are relate to the physical properties of the interacting molecules and their environment allows rational design of molecules and materials that interact in speci?c and desired ways. This book presents a signi?cant and up-to-date review of the various recognition elements, their immobilization, characterization techniques by a panel of dist- guished scientists. This work is a comprehensive approach to the recognition receptors area presenting a thorough knowledge of the subject and an effective integration of these receptors on sensor surfaces in order to appropriately convey the state-of the-art fundamentals and applications of the most innovative approaches.




Medical Biotechnology, Biopharmaceutics, Forensic Science and Bioinformatics


Book Description

This book covers a range of topics on exploiting Nigeria’s mega biodiversity for food security and health; DNA forensic science and its applications; medical biotechnology and biopharmaceutics; medicinal and underutilized plants; impact and mitigation of antibiotic resistance; bioinformatics applications; medical insect biotechnology; etc. The book will be useful reference material for the scientists and researchers working in the fields of nutraceuticals, molecular diagnostics and DNA forensics, biopharmaceuticals and medical biotechnology, nanotechnology, antimicrobials from indigenous plant species, bioinformatics, etc. Emphasizes recent advances in biotechnologies that will help in tackling emerging global health challenges Provides detailed information on how to harness indigenous bioresources including microorganisms and plants for healthcare delivery Introduces new frontiers in the areas of molecular diagnostics and DNA forensic science and bioinformatics with case studies, recent advances in medical insect biotechnology and molecular genetics of pest use towards the exploitation of arthropod midgut components to develop interventions against infectious diseases Reviews bioactive molecules derived from commonly used and underutilized medicinal plants that could be used to develop novel drugs for improved healthcare delivery Discusses current approaches in medical and biopharmaceutical biotechnology, deployment of inexpensive genomics-based vector surveillance for effective disease outbreak prediction and control of mosquito-borne viruses Hajiya Mairo Inuwa, Ph.D., is Professor in the Department of Biochemistry and Formerly Director, Centre for Biotechnology Research and Training (CBR&T), Ahmadu Bello University, Zaria, Nigeria. Ifeoma Maureen Ezeonu, Ph.D., is Professor of Medical Microbiology and Molecular Genetics in the Department of Microbiology, University of Nigeria, Nsukka, Nigeria. Charles Oluwaseun Adetunji, Ph.D., is Associate Professor of Microbiology and Biotechnology and Director of Intellectual Property and Technology Transfer, Edo State University, Uzairue, Nigeria. Abubakar Gidado, Ph.D., is Professor of Biochemistry and Director of North-East Zonal Biotechnology Centre of Excellence at the University of Maiduguri. Emmanuel Olufemi Ekundayo, Ph.D., is Associate Professor of Medical Microbiology and Microbial Genetics, Michael Okpara University of Agriculture, Umudike, Nigeria. Abdulrazak B. Ibrahim, Ph.D., is a Capacity Development Expert at the Forum for Agricultural Research in Africa (FARA) and Associate Professor of Biochemistry, Ahmadu Bello University, Zaria, Nigeria. Benjamin Ewa Ubi, Ph.D., is a Professor of Plant Breeding and Biotechnology and Director, Biotechnology Research and Development Centre, Ebonyi State University, Abakaliki, Nigeria.




Handbook of Nanosensors


Book Description




Global Health Security


Book Description

With our highly connected and interdependent world, the growing threat of infectious diseases and public health crisis has shed light on the requirement for global efforts to manage and combat highly pathogenic infectious diseases and other public health crisis on an unprecedented level. Such disease threats transcend borders. Reducing global threats posed by infectious disease outbreaks – whether naturally caused or resulting from a deliberate or accidental release – requires efforts that cross the disaster management pillars: mitigation, preparedness, response and recovery. This book addresses the issues of global health security along 4 themes: Emerging Threats; Mitigation, Preparedness, Response and Recovery; Exploring the Technology Landscape for Solutions; Leadership and Partnership. The authors of this volume highlight many of the challenges that confront our global security environment today. These range from politically induced disasters, to food insecurity, to zoonosis and terrorism. More optimistically, the authors also present some advances in technology that can help us combat these threats. Understanding the challenges that confront us and the tools we have to overcome them will allow us to face our future with confidence.