Biosurveillance and Biosecurity


Book Description

This book constitutes the refereed proceedings of the International Workshop on Biosurveillance and Biosecurity, BioSecure 2008, held in Raleigh, NC, USA, in December 2008. The 18 revised full papers presented together with one invited paper were carefully reviewed and selected from numerous submissions. The papers are organized in topical sections on informatics infrastructure and policy considerations; network-based data analytics; biosurveillance models and outbreak detection; model assessment and case studies; environmental biosurveillance and case studies.




Biosecurity and Bioterrorism


Book Description

Biosecurity and Bioterrorism, Second Edition, takes a holistic approach to biosecurity, with coverage of pathogens, prevention, and response methodology. It addresses these hazards in the context of vulnerability assessments and the planning strategies government and industry can use to prepare for and respond to such events. The book is organized into four thematic sections: Part I provides a conceptual understanding of biowarfare, bioterrorism and the laws we have to counteract this; Part II investigates known bioagents and the threat from emerging diseases; Part III focuses on agricultural terrorism and food security; and Part IV outlines international, US, and local initiatives for biodefense and biosecurity. Case studies illustrate biodefense against both intentional terrorism and natural outbreaks. Covers emerging threats of pandemic influenza, antibiotic resistant strains of bacterial pathogens, and severe respiratory diseases caused by novel viruses Offers increased international coverage, including initiatives to counter biological weapons and threats, and food security Updated throughout with latest protocols for dealing with biological threats and new case studies Includes online instructor ancillaries - PowerPoint lecture slides, test questions, and an instructor manual, for increased classroom functionality




Environmental Biodetection and Human Biosurveillance Research and Development for National Security


Book Description

Environmental biodetection (BD) and human biosurveillance (BSV) are part of the foundation of national biodefense. The Department of Homeland Security's (DHS's) Science and Technology Directorate (S&T) chemical and biological defense (CBD) research and development (R&D) portfolio improves technologies and operations in both of these areas. In the context of evolving technologies, greater adversary capabilities, and unpredictable federal budgets, this report examines S&T's CBD R&D portfolio to identify priorities for future investments. The policy context includes multiple national strategies addressing biodefense, biosurveillance, health security, and national security; multiple federal agencies have missions and programming in this space. The R&D outputs of most CBD projects and most projects in illustrative inventories of non-S&T CBD R&D are not ready for deployment. S&T's CBD R&D has focused more on environmental BD than on human BSV. While S&T has supported some projects to develop tests for environmental or human samples, other federal agencies have supported more studies in this area. There is less R&D-supported by S&T or other sources-that targets system configuration or concept of operations (CONOPS). The recommendations are to (1) develop a DHS strategic plan for environmental BD and human BSV R (2) prioritize environmental BD over human BSV for future DHS R&D investments, given the department's unique role in this area; (3) prioritize R&D addressing CONOPS; (4) actively monitor R&D supported by other agencies, and adapt relevant outputs to meet DHS needs; (5) shorten the timeline for real-world application by prioritizing midstage and later stage R&D over early stage research.




Biosecurity in the Global Age


Book Description

"The renewed threat of biological weapons highlights the importance of crafting policy responses informed by the rule of law. This book explores patterns in recent governance initiatives and advocates building a "global biosecurity concert" as a way to address the threats presented by biological weapons and infectious diseases in the early 21st century."--BOOK JACKET.




Biosecurity


Book Description

Learn how to assess and prevent biosecurity threats to protect public health and national security With contributions from experts in all facets of biosecurity, this book explains the fundamental elements of biosecurity as well as the related concepts of biosafety and biosurety, detailing how all three concepts fit within the framework of biodefense. Readers are then given the tools needed to assess and prevent biosecurity threats and vulnerabilities. The book explores the nature of biosecurity threats to research laboratories as well as to agriculture, food, and mass transit. Moreover, readers will learn how to apply principles of biosecurity to assess epidemics and protect public health. Biosecurity takes a detailed look at today's biosecurity policy, explaining how it is likely to evolve given current and potential threats to national security. The authors stress the importance of education and advocacy, helping readers develop effective programs to build public awareness and preparedness. The book also presents a novel tool to assess the effectiveness of laboratory biosafety and biosecurity programs. Biosecurity is divided into four parts: Part I: An Introduction to Biosecurity Part II: Elements of Biosecurity Part III: Biosecurity in Various Sectors Part IV: Biosecurity Policy, Bioterrorism, and the Future This book will instill a deep understanding of what biosecurity is and what it is not. It urges readers to think about the importance of biosecurity as it relates to national security, safety, and health. By exposing major flaws in global biosecurity thinking, Biosecurity sets forth a clear pathway to correct those errors and build stronger biosecurity programs.




Applied Biosecurity: Global Health, Biodefense, and Developing Technologies


Book Description

This book describes an adaptable biothreat assessment process to complement overall biorisk management programs, incorporating threat management and the unique natures of biological assets. Further, this book examines the nexus between public health, international security, and developing technologies, building a case for augmenting biosecurity to levels beyond the laboratory constraints. With the face of biological and biomedical sciences changing, this book describes how with proper biosecurity development, these can become assets, rather than liabilities, to secure our world from natural and man-made biological disasters. The world is changing rapidly with respect to developing threats, such as terrorism, and dual-use technologies, such as synthetic biology, that are challenging how we think about biosafety and biosecurity. Further, the fields of public health and international security are colliding, as both of these share the common enemy: intentional or natural biological incidents. To date, biosecurity has been limited to laboratory-level application, and complicating efforts, and lacks credentialed biosecurity professionals skilled in both the biological sciences and threat management techniques. The result is a fragmented field of practice, with tremendous need, from the lab to the outbreak. Underpinning these principles is the SARS-CoV-2 coronavirus pandemic, providing a historic milestone to examine biosecurity through a global lens. This book describes biosecurity as a set of practices and principles to be augmented out of the constrained laboratory environment, and applied to larger efforts, such as international threat reduction and biological incident management.




Biological Engagement Programs: Reducing Threats and Strengthening Global Health Security Through Scientific Collaboration


Book Description

Biological engagement programs are a set of projects or activities between partner countries that strengthen global health security to achieve mutually beneficial outcomes. Engagement programs are an effective way to work collaboratively towards a common threat reduction goal, usually with a strong focus on strengthening health systems and making the world a safer place. Cooperative programs are built upon trust and sharing of information and resources to increase the capacity and capabilities of partner countries. Biological engagement programs reduce the threat of infectious disease with a focus on pathogens of security concern, such as those pathogens identified by the U.S. Government as Biological Select Agent and Toxins. These programs seek to develop technical or scientific relationships between countries to combat infectious diseases both in humans and animals. Through laboratory biorisk management, diagnostics, pathogen detection, biosurveillance and countermeasure development for infectious diseases, deep relationships are fostered between countries. Biological engagement programs are designed to address dual-use issues in pathogen research by promoting responsible science methodologies and cultures. Scientific collaboration is a core mechanism for engagement programs are designed to strengthen global health security, including prevention of avoidable epidemics; detection of threats as early as possible; and rapid and effective outbreak response. This Research Topic discusses Biological Engagement Programs, highlighting the successes and challenges of these cooperative programs. Articles in this topic outlined established engagement programs as well as described what has been learned from historical cooperative engagement programs not focused on infectious diseases. Articles in this topic highlighted selected research, trainings, and programs in Biological Engagement Programs from around the world. This Topic eBook first delves into Policies and Lessons Learned; then describes Initiatives in Biosafety & Biosecurity; the core of this work documents Cooperative Research Results from the field; then lastly the Topic lays out potential Future Directions to the continued success of the World’s cooperative science in reducing the threat of infectious diseases.




Biosurveillance


Book Description

"A biological event, such as a naturally occurring pandemic or a terrorist attack with a weapon of mass destruction, could have catastrophic consequences for the nation. This potential threat underscores the importance of a national biosurveillance capability -- that is, the ability to detect biological events of national significance to provide early warning and information to guide public health and emergency response. The 9/11 Commission Act of 2007 addresses this capability, in part, by creating National Biosurveillance Integration Center within the Department of Homeland Security (DHS); it was tasked with integrating information from human health, animal, plant, food, and environmental monitoring systems across the federal government, to improve the likelihood of identifying a biological event at an earlier stage. In recent years, NBIC's budget has ranged from $10 million to $13 million annually. GAO was asked to evaluate NBIC. This report discusses the (1) extent to which NBIC is implementing its roles as a biosurveillance integrator, and (2) options for improving such integration. To conduct this work, GAO reviewed NBIC products and activities; conducted interviews and surveyed 19 federal partners, 11 of which have key roles in biosurveillance; interviewed NBIC officials; and analyzed the 9/11 Commission Act, NBIC Strategic Plan, and National Strategy for Biosurveillance"--Preliminary page.




Biocrisis


Book Description

This book examines the recent intersection of national security and public health regarding biological threats to the U.S. populace and proposes improvements to the executive and legislative development of U.S. policy addressing biological threat mitigation. Over the last 20 years, the national security community has engaged with disease-related issues that have traditionally been the scope of public health agencies. The federal government's response has been to create a single national biodefense strategy, which has been largely ineffective in improving conditions due to poor terminology, a lack of leadership, and a failure to assess government programs. Applying a public policy framework, Albert J. Mauroni examines how the government addresses biological threats-including disease prevention, bioterrorism response, military biodefense, biosurety, and agricultural biosecurity and food safety. He proposes a new approach to countering biological threats, arguing that lead agencies should focus on implementing discrete portfolios with annual assessments against clear and achievable objectives.




Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories


Book Description

During July 10-13, 2011, 68 participants from 32 countries gathered in Istanbul, Turkey for a workshop organized by the United States National Research Council on Anticipating Biosecurity Challenges of the Global Expansion of High-containment Biological Laboratories. The United States Department of State's Biosecurity Engagement Program sponsored the workshop, which was held in partnership with the Turkish Academy of Sciences. The international workshop examined biosafety and biosecurity issues related to the design, construction, maintenance, and operation of high-containment biological laboratories- equivalent to United States Centers for Disease Control and Prevention biological safety level 3 or 4 labs. Although these laboratories are needed to characterize highly dangerous human and animal pathogens, assist in disease surveillance, and produce vaccines, they are complex systems with inherent risks. Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories summarizes the workshop discussion, which included the following topics: Technological options to meet diagnostic, research, and other goals; Laboratory construction and commissioning; Operational maintenance to provide sustainable capabilities, safety, and security; and Measures for encouraging a culture of responsible conduct. Workshop attendees described the history and current challenges they face in their individual laboratories. Speakers recounted steps they were taking to improve safety and security, from running training programs to implementing a variety of personnel reliability measures. Many also spoke about physical security, access controls, and monitoring pathogen inventories. Workshop participants also identified tensions in the field and suggested possible areas for action.