Biotechnology


Book Description




Animal Biotechnology


Book Description

Genetic-based animal biotechnology has produced new food and pharmaceutical products and promises many more advances to benefit humankind. These exciting prospects are accompanied by considerable unease, however, about matters such as safety and ethics. This book identifies science-based and policy-related concerns about animal biotechnologyâ€"key issues that must be resolved before the new breakthroughs can reach their potential. The book includes a short history of the field and provides understandable definitions of terms like cloning. Looking at technologies on the near horizon, the authors discuss what we know and what we fear about their effectsâ€"the inadvertent release of dangerous microorganisms, the safety of products derived from biotechnology, the impact of genetically engineered animals on their environment. In addition to these concerns, the book explores animal welfare concerns, and our societal and institutional capacity to manage and regulate the technology and its products. This accessible volume will be important to everyone interested in the implications of the use of animal biotechnology.




Biodefense in the Age of Synthetic Biology


Book Description

Scientific advances over the past several decades have accelerated the ability to engineer existing organisms and to potentially create novel ones not found in nature. Synthetic biology, which collectively refers to concepts, approaches, and tools that enable the modification or creation of biological organisms, is being pursued overwhelmingly for beneficial purposes ranging from reducing the burden of disease to improving agricultural yields to remediating pollution. Although the contributions synthetic biology can make in these and other areas hold great promise, it is also possible to imagine malicious uses that could threaten U.S. citizens and military personnel. Making informed decisions about how to address such concerns requires a realistic assessment of the capabilities that could be misused. Biodefense in the Age of Synthetic Biology explores and envisions potential misuses of synthetic biology. This report develops a framework to guide an assessment of the security concerns related to advances in synthetic biology, assesses the levels of concern warranted for such advances, and identifies options that could help mitigate those concerns.







Introduction to Food Biotechnology


Book Description

Universities throughout the US and the rest of the world offer Food Biotechnology courses. However, until now, professors lacked a single, comprehensive text to present to their students. Introduction to Food Biotechnology describes, explains, and discusses biotechnology within the context of human nutrition, food production, and food processing. Written for undergraduate students in Food Science and Nutrition who do not have a background in molecular biology, it provides clear explanations of the broad range of topics that comprise the field of food biotechnology. Students will gain an understanding of the methods and rationales behind the genetic modification of plants and animals, as well as an appreciation of the associated risks to the environment and to public health. Introduction to Food Biotechnology examines cell culture, transgenic organisms, regulatory policy, safety issues, and consumer concerns. It covers microbial biotechnology in depth, emphasizing applications to the food industry and methods of large-scale cultivation of microbes and other cells. It also explores the potential of biotechnology to affect food security, risks, and other ethical problems. Biotechnology can be used as a tool within many disciplines, including food science, nutrition, dietetics, and agriculture. Using numerous examples, Introduction to Food Biotechnology lays a solid foundation in all areas of food biotechnology and provides a comprehensive review of the biological and chemical concepts that are important in each discipline. The book develops an understanding of the potential contributions of food biotechnology to the food industry, and towards improved food safety and public health.




Recombinant DNA and Biotechnology


Book Description

Written in clear, easy–to–understand language, this best–selling reference text and activities manual offers easy–to–implement lessons and classroom activities. Part I covers basic molecular biology, and Part II offers imaginative dry labs and wet labs that can be done by both college and precollege students. Part III is an innovative section addressing the social issues and public concerns of biotechnology. Extensive appendixes provide important background information on basic laboratory techniques and teaching resources, including overhead masters and templates. Adopted by numerous school systems, this unique book is an outgrowth of molecular biology and biotechnology teaching workshops. All of the exercises and lab activities have been extensively tested in the classroom by hundreds of high school teachers. Recombinant DNA and Biotechnology is designed to interest an international teaching audience and will enable all instructors to teach a reasonable amount of molecular biology and genetic engineering to students. No other book makes it so easy or compelling for teachers to incorporate the "new biology" into their biology, biological sciences, or general science curriculum. Recombinant DNA and Biotechnology: A Guide for Teachers will enable college and precollege teachers to plan and conduct an exciting and contemporary course on the basic principles, essential laboratory activities, and relevant social issues and concerns attendant to today′s molecular biology revolution. In addition to the complete text of the student edition, A Guide for Teachers also contains the answers to all discussion questions and extra background information and material on the scientific principles involved.




Emerging Consequences of Biotechnology


Book Description

The principal message of this book is that thermodynamics and statistical mechanics will benefit from replacing the unfortunate, misleading and mysterious term "entropy" with a more familiar, meaningful and appropriate term such as information, missing information or uncertainty. This replacement would facilitate the interpretation of the "driving force" of many processes in terms of informational changes and dispel the mystery that has always enshrouded entropy. It has been 140 years since Clausius coined the term "entropy"; almost 50 years since Shannon developed the mathematical theory of "information"--Subsequently renamed "entropy." In this book, the author advocates replacing "entropy" by "information," a term that has become widely used in many branches of science. The author also takes a new and bold approach to thermodynamics and statistical mechanics. Information is used not only as a tool for predicting distributions but as the fundamental cornerstone concept of thermodynamics, held until now by the term "entropy." The topics covered include the fundamentals of probability and information theory; the general concept of information as well as the particular concept of information as applied in thermodynamics; the re-derivation of the Sackur-Tetrode equation for the entropy of an ideal gas from purely informational arguments; the fundamental formalism of statistical mechanics; and many examples of simple processes the "driving force" for which is analyzed in terms of information.




Forest Health and Biotechnology


Book Description

The American chestnut, whitebark pine, and several species of ash in the eastern United States are just a few of the North American tree species that have been functionally lost or are in jeopardy of being lost due to outbreaks of pathogens and insect pests. New pressures in this century are putting even more trees at risk. Expanded human mobility and global trade are providing pathways for the introduction of nonnative pests for which native tree species may lack resistance. At the same time, climate change is extending the geographic range of both native and nonnative pest species. Biotechnology has the potential to help mitigate threats to North American forests from insects and pathogens through the introduction of pest-resistant traits to forest trees. However, challenges remain: the genetic mechanisms that underlie trees' resistance to pests are poorly understood; the complexity of tree genomes makes incorporating genetic changes a slow and difficult task; and there is a lack of information on the effects of releasing new genotypes into the environment. Forest Health and Biotechnology examines the potential use of biotechnology for mitigating threats to forest tree health and identifies the ecological, economic, and social implications of deploying biotechnology in forests. This report also develops a research agenda to address knowledge gaps about the application of the technology.




Glossary of Biotechnology Terms, Fourth Edition


Book Description

Even if you studied biotechnology in school, if you haven't stayed current, it's not likely you'll be able to speak the same language as today's biotech scientists. The same is even truer for nanotechnology where everything gets smaller and smaller, except the terminology required to navigate it. In the Glossary of Biotechnology and Nanobiotechnology Terms, Fourth Edition, Kimball Nill continues to improve upon the reference that for over a decade has helped thousands of professionals, including scientists, attorneys, government workers, lobbyists, venture capitalists, and university tech transfer staff, to communicate successfully with those working on the cutting edge of modern science. Now in its fourth edition, Nill has taken the much appreciated step of adding nanotechnology to his glossary. Just by casually perusing the Glossary of Biotechnology and Nanobiotechnology Terms, Fourth Edition you will learn a number of enlightening facts. Even those in related sciences will be surprised to discover what the language unveils. The Glossary of Biotechnology and Nanobiotechnology Terms, Fourth Edition is a handy reference designed for people with little or no training in the biological and chemical sciences, as well as scientists communicating from other disciplines. Unlike other glossaries, this one is both informative and completely accessible. Instead of looking up one term to end up mired in equally difficult terminology, this intelligently designed volume follows what the author refers to as a Reference Chain that steadily leads you to simpler more common terminology, down to a level that anyone with a high school education will be able to understand. The definitions are written utilizing words that enable you to conceptualize the idea embodied in the term, with explanations based on analogy whenever possible. Consider this example: Suppose you just received a funding request, a faculty memo, or patent concern that refers to A-DNA, which happens to be the first definition in the Glossary. A-DNA A particular right-handed helical form of DNA (possessing 11 base pairs per turn), which is the form that DNA molecules exist in when they are partially dehydrated. A-form DNA is found in fibers at 75% relative humidity and requires the presence of sodium, potassium, or cesium as the counterion. Instead of lying flat, the bases are tilted with respect to the helical axis, and there are more base pairs per turn. The A-form is biologically interesting because it is probably very close to the conformation adopted by DNA-RNA hybrids or by RNA-RNA double-stranded regions. The reason is that the presence of the 2'2 hydroxyl group prevents RNA from lying in the B-form. See also B-DNA, DNA-RNA HYBRID, DEOXYRIBONUCLEIC ACID (DNA), BASE PAIR (bp) But then after looking at the above definition, you wonder what exactly is a DNA-RNA Hybrid? DNA-RNA Hybrid A double helix that consists of one chain of DNA hydrogen-bonded to a chain of RNA by means of complementary base pairs. See also HYBRIDIZATION (MOLECULAR GENETICS), HYBRIDIZATION (PLANT GENETICS), DOUBLE HELIX ...however while you've often heard mention of a double helix, you were never quite sure what that meant.... Double Helix The natural coiled conformation of two complementary, antiparallel DNA chains. This structure was first put forward by Watson and Crick in 1953. See also DEOXYRIBONUCLEIC ACID (DNA) And that might brings you to ask, Do you really actually know what DNA is? Deoxyribonucleic Acid (DNA) Discovered by Frederick Miescher in 1869, it is the chemical basis for genes. The chemical building blocks (molecules) of which genes (i.e., paired nucleotide units that code for a protein to be produced by a cell's machinery, such as its ribosomes) are constructed. Every inherited characteristic has its origin somewhere in the code of the organism's complement of DNA. The code is made up of subunits called nucleic acids. The sequence of the four nucleic acids is interpreted by certain molecular systems in order to produce the proteins required by an organism. The structure of the DNA molecule was elucidated in 1953.... The Glossary of Biotechnology and Nanobiotechnology Terms, Fourth Edition is packed with over 400 pages of exceptionally well-organized and cross-referenced terminology, making it an essential reference for anyone working directly or indirectly with those pioneering the frontiers of modern biology.




The Evolution of Biotechnology


Book Description

This book traces the evolution of biotechnology from prehistoric organismal manipulation by our first settled ancestors through to speculation about future directions for the technology as it increasingly intersects with other high technologies such as IT and Nanotech. The trajectory is demonstrated by various events throughout history that have intersected or built on one another to lead to the forward progression of a technology.