Translational Research in Traumatic Brain Injury


Book Description

Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme




Neural Plasticity Across the Lifespan


Book Description

Neural Plasticity Across the Lifespan reviews the recent scientific developments which are transforming our understanding of the human brain. For many years it was thought that modifications to the structural and functional organization of the brain were limited to a short early period of life, "the critical period", and, in adults, to the memory system. Recent research suggests that on the contrary we should see the human brain as a flexible structure, which adapts and modifies in response to learning, sensory experience, age and disease. The book provides an integrated overview of contemporary research on neural plasticity - the process by which the brain can change in structure and function to cope with new experiences and react to the effects of acquired damage or sensory deprivation. It reviews data on plasticity in the developing brain, looking at both typical and atypical development, alongside clinical and observational research on the adult population. It covers a number of key topics, including: different forms of neural plasticity factors affecting neural plasticity (ageing and gender), neural plasticity in language acquisition, memory and bodily self-consciousness mechanisms of repair – plasticity following sensory deprivation and acquired brain damage. This is an accessible overview of an emerging field of research which has fundamental implications for how we perceive our potential to change throughout our lives. It will be essential reading for all students of cognitive development, cognitive neuroscience and lifespan development.




The Neuroscience of Adolescence


Book Description

Written by an award-winning developmental neuroscientist, this is a comprehensive and cutting-edge account of the latest research on the adolescent brain.




The Neural Bases of Multisensory Processes


Book Description

It has become accepted in the neuroscience community that perception and performance are quintessentially multisensory by nature. Using the full palette of modern brain imaging and neuroscience methods, The Neural Bases of Multisensory Processes details current understanding in the neural bases for these phenomena as studied across species, stages of development, and clinical statuses. Organized thematically into nine sub-sections, the book is a collection of contributions by leading scientists in the field. Chapters build generally from basic to applied, allowing readers to ascertain how fundamental science informs the clinical and applied sciences. Topics discussed include: Anatomy, essential for understanding the neural substrates of multisensory processing Neurophysiological bases and how multisensory stimuli can dramatically change the encoding processes for sensory information Combinatorial principles and modeling, focusing on efforts to gain a better mechanistic handle on multisensory operations and their network dynamics Development and plasticity Clinical manifestations and how perception and action are affected by altered sensory experience Attention and spatial representations The last sections of the book focus on naturalistic multisensory processes in three separate contexts: motion signals, multisensory contributions to the perception and generation of communication signals, and how the perception of flavor is generated. The text provides a solid introduction for newcomers and a strong overview of the current state of the field for experts.




Cognitive Plasticity in Neurologic Disorders


Book Description

This volume makes clear that the cognitive and behavioural symptoms of neurologic disorders and syndromes are dynamic and changing. Each chapter describes the neuroplastic processes at work in a particular condition, giving rise to these ongoing cognitive changes.




The Paradoxical Brain


Book Description

The Paradoxical Brain focuses on a range of phenomena in clinical and cognitive neuroscience that are counterintuitive and go against the grain of established thinking. The book covers a wide range of topics by leading researchers, including: • Superior performance after brain lesions or sensory loss • Return to normal function after a second brain lesion in neurological conditions • Paradoxical phenomena associated with human development • Examples where having one disease appears to prevent the occurrence of another disease • Situations where drugs with adverse effects on brain functioning may have beneficial effects in certain situations A better understanding of these interactions will lead to a better understanding of brain function and to the introduction of new therapeutic strategies. The book will be of interest to those working at the interface of brain and behaviour, including neuropsychologists, neurologists, psychiatrists and neuroscientists.







Cognitive Enhancement in Schizophrenia and Related Disorders


Book Description

A practical guide on how to assess and treat schizophrenia and related disorders using cognitive rehabilitation.




Stroke Rehabilitation


Book Description

Stroke Rehabilitation: Insights from Neuroscience and Imaging informs and challenges neurologists, rehabilitation therapists, imagers, and stroke specialists to adopt more restorative and scientific approaches to stroke rehabilitation based on new evidence from neuroscience and neuroimaging literatures. The fields of cognitive neuroscience and neuroimaging are advancing rapidly and providing new insights into human behavior and learning. Similarly, improved knowledge of how the brain processes information after injury and recovers over time is providing new perspectives on what can be achieved through rehabilitation. Stroke Rehabilitation explores the potential to shape and maximize neural plastic changes in the brain after stroke from a multimodal perspective. Active skill based learning is identified as a central element of a restorative approach to rehabilitation. The evidence behind core learning principles as well as specific learning strategies that have been applied to retrain lost functions of movement, sensation, cognition and language are also discussed. Current interventions are evaluated relative to this knowledge base and examples are given of how active learning principles have been successfully applied in specific interventions. The benefits and evidence behind enriched environments is reviewed with examples of potential application in stroke rehabilitation. The capacity of adjunctive therapies, such as transcranial magnetic stimulation, to modulate receptivity of the damaged brain to benefit from behavioral interventions is also discussed in the context of this multimodal approach. Focusing on new insights from neuroscience and imaging, the book explores the potential to tailor interventions to the individual based on viable brain networks.