Buell V. Casellas


Book Description




Buell V. Casellas


Book Description




Molecular and Cell Biology of Cancer


Book Description

This textbook takes you on a journey to the basic concepts of cancer biology. It combines developmental, evolutionary and cell biology perspectives, to then wrap-up with an integrated clinical approach. The book starts with an introductory chapter, looking at cancer in a nut shell. The subsequent chapters are detailed and the idea of cancer as a mass of somatic cells undergoing a micro-evolutionary Darwinian process is explored. Further, the main Hanahan and Weinberg “Hallmarks of Cancer” are revisited. In most chapters, the fundamental experiments that led to key concepts, connecting basic biology and biomedicine are highlighted. In the book’s closing section all of these concepts are integrated in clinical studies, where molecular diagnosis as well as the various classical and modern therapeutic strategies are addressed. The book is written in an easy-to-read language, like a one-on-one conversation between the writer and the reader, without compromising the scientific accuracy. Therefore, this book is suited not only for advanced undergraduates and master students but also for patients or curious lay people looking for a further understanding of this shattering disease







Drug Discovery and Evaluation


Book Description

This reference book contains a comprehensive selection of the most frequently used assays for reliably detecting pharmacological effects of potential drugs, including tests for cardiovascular, analgesic, psychotropic, metabolic, endocrine, respiratory, renal, and immunomodulatory activities. Each of the over 700 assays comprises a detailed protocol with the purpose and rationale of the method, a description of the experimental procedure, a critical assessment of the results and their pharmacological and clinical relevance, and pertinent references. Identification of specific tests is facilitated by the enclosed CD-ROM which allows for a quick and full text research. An appendix with guidelines and legal regulations for animal experiments in various countries will help to plan these experiments properly in accordance with the welfare of laboratory animals.




Viral, Parasitic, Bacterial, and Fungal Infections


Book Description

Viral, Parasitic, Bacterial, and Fungal Infections: Antimicrobial, Host Defense, and Therapeutic Strategies highlight diverse types of infections, including viral, bacterial, parasitic, fungal, and the therapeutic efficacy of antibiotics, antivirals, antifungals and other medications, nutraceuticals, and phytotherapeutics. This book addresses the molecular, pathophysiological, and cellular pathways involved in the process of infection. It also examines the host defense mechanisms modulated by innate and adaptive immunity. The book starts off with an introduction, which includes etiology, pathophysiology, and diagnosis of infections. It then goes on to cover a wide spectrum of salient features involved in viral, bacterial, parasitic, and fungal infections and effective therapeutic strategies. In addition, there is a complete section of eight chapters elaborating the detailed aspects of COVID-19 infections, Mucormycosis, Omicron, and strategic vaccines and therapeutics. The book further goes on to discuss novel antibiotics, vaccines, bromhexine, boron compounds, phytotherapeutics, and aspects on boosting immune competence. Contributed by experts in the fields of viral, parasitic, bacterial, and fungal infections, the book comprehensively details the various types of infections such as herpes and COVID-19, their molecular mechanisms, and treatment strategies for those engaged in the research of infectious diseases. - Details the pathophysiology of various classes of infections - Examines mechanisms of pathogenesis, immunity, and therapeutics in bacterial, viral, and eukaryotic infectious diseases - Discusses various aspects on herpes, COVID-19 infections, Mucormycosis, Omicron, vaccines, and therapeutics - Covers the salient features on zoonosis, prion disease, and diabetic foot infections - Provides therapeutic strategies of using new antibiotics, vaccines, bromhexine, boron compounds, structurally diverse phytotherapeutics, immune enhancers, and other modalities for treating infections







Diagnostic Nuclear Medicine


Book Description

2nd edition - totally updated and revised. Provides the latest update on procedures in nuclear medicine. Documents the role of PET in oncology and introduces dual modality imaging with PET/CT. Includes sections on molecular imaging and future prospects. Represents an adjunct to standard knowledge of diagnostic nuclear medicine.




Composer Genealogies


Book Description

Throughout the western classical tradition, composers have influenced and been influenced by their students and teachers. Many musicians frequently add to their personal acclaim by naming their teachers and the lineage through which they were taught. Until now, the relationships between composers have remained uncataloged and understudied, but with enough research, it is possible to document entire schools of composition. Composer Genealogies: A Compendium of Composers, Their Teachers, and Their Students is the first volume to gather the genealogies of more than seventeen thousand classical composers in a single volume. Functioning as its own fully cross-referenced index, this volume lists composers and their dates, followed by their teachers and notable students. A short introduction presents the parameters by which composers were selected and provides a survey of the literature available for further study. Gathering records and information from reference books, university websites, obituaries, articles, composers’ websites, and even direct contact with some composers, Pfitzinger creates a valuable resource for music researchers, composers, and performers.