Author : Sergey V. Dorozhkin
Publisher : CRC Press
Page : 863 pages
File Size : 16,44 MB
Release : 2012-06-04
Category : Science
ISBN : 9814364177
Due to a great chemical similarity with the biological calcified tissues, many calcium orthophosphates possess remarkable biocompatibility and bioactivity. Materials scientists use this property extensively to construct artificial bone grafts that are either entirely made of or only surface-coated with the biologically relevant calcium orthophospha
Author : Sergey V. Dorozhkin
Publisher : Nova Science Pub Incorporated
Page : 169 pages
File Size : 15,28 MB
Release : 2010-01
Category : Medical
ISBN : 9781608769414
In this book, the state-of-the-art of calcium orthophosphate-based biocomposites and hybrid biomaterials suitable for biomedical applications is presented. This subject belongs to a rapidly expanding area of science and research because these types of biomaterials offer many significant and exciting possibilities for hard tissue regeneration. Through the successful combination of the desired properties of matrix materials with those of fillers (in such systems, calcium orthophosphates might play either role), innovative bone graft biomaterials can be designed. The book starts with an introduction to locate the reader. Further, general information on composites and hybrid materials, including a brief description of their major constituents are presented. Various types of calcium orthophosphate-based bone-analogue biocomposites and hybrid biomaterials, those are either already in use or being investigated for various biomedical applications are then extensively discussed. Many different formulations in terms of the material constituents, fabrication technologies, structural and bioactive properties, as well as both in vitro and in vivo characteristics have already been proposed. Among the others, the nano-structurally controlled biocomposites, those with nano-sized calcium orthophosphates, biomimetically-fabricated formulations with collagen, chitin and/or gelatin, as well as various functionally graded structures seem to be the most promising candidates for clinical applications. The specific advantages of using calcium orthophosphate-based biocomposites and hybrid biomaterials in the selected applications are highlighted. As the way from a laboratory to a hospital is a long one and the prospective biomedical candidates have to meet many different necessities, the critical issues and scientific challenges that require further research and development have been examined as well.
Author : Sergey V. Dorozhkin
Publisher : CRC Press
Page : 119 pages
File Size : 14,48 MB
Release : 2018-09-29
Category : Medical
ISBN : 0429799802
This title gives an overview of composites and biocomposites. It discusses the history of CaPO4/ /polymer biocomposites and hybrid biomaterials, as well as analyzing the latest developments in the field. It also covers bioactivity and biodegradation of CaPO4-based biomaterials.
Author : Iulian Antoniac
Publisher : John Wiley & Sons
Page : 400 pages
File Size : 26,62 MB
Release : 2019-04-04
Category : Technology & Engineering
ISBN : 1119372143
Provides comprehensive coverage of the research into and clinical uses of bioceramics and biocomposites Developments related to bioceramics and biocomposites appear to be one the most dynamic areas in the field of biomaterials, with multiple applications in tissue engineering and medical devices. This book covers the basic science and engineering of bioceramics and biocomposites for applications in dentistry and orthopedics, as well as the state-of-the-art aspects of biofabrication techniques, tissue engineering, remodeling, and regeneration of bone tissue. It also provides insight into the use of bionanomaterials to create new functionalities when interfaced with biological molecules or structures. Featuring contributions from leading experts in the field, Bioceramics and Biocomposites: From Research to Use in Clinical Practice offers complete coverage of everything from extending the concept of hemopoietic and stromal niches, to the evolution of bioceramic-based scaffolds. It looks at perspectives on and trends in bioceramics in endodontics, and discusses the influence of newer biomaterials use on the structuring of the clinician’s attitude in dental practice or in orthopedic surgery. The book also covers such topics as biofabrication techniques for bioceramics and biocomposites; glass ceramics: calcium phosphate coatings; brain drug delivery bone substitutes; and much more. Presents the biggest trends in bioceramics and biocomposites relating to medical devices and tissue engineering products Systematically presents new information about bioceramics and biocomposites, developing diagnostics and improving treatments and their influence on the clinicians' approaches Describes how to use these biomaterials to create new functionalities when interfaced with biological molecules or structures Offers a range of applications in clinical practice, including bone tissue engineering, remodeling, and regeneration Delineates essential requirements for resorbable bioceramics Discusses clinical results obtained in dental and orthopedic applications Bioceramics and Biocomposites: From Research to Use in Clinical Practice is an excellent resource for biomaterials scientists and engineers, bioengineers, materials scientists, and engineers. It will also benefit mechanical engineers and biochemists who work with biomaterials scientists.
Author : Sergey V. Dorozhkin
Publisher : John Wiley & Sons
Page : 416 pages
File Size : 12,22 MB
Release : 2016-03-17
Category : Technology & Engineering
ISBN : 3527699309
Reflecting the advances made in recent years, this is a comprehensive overview of calcium orthophosphates for bioceramics and biocomposites with a special focus on the detailed description of all those available, including their biological and geological occurrence, preparation, chemical composition, structure-property relationships and applications. In particular, the book discusses the suitability of these orthophosphates for biomedical applications and their use as bone grafts in surgery and medicine. The result is a useful reference for researchers with an academic, medical or commercial background.
Author : Larry L Hench
Publisher : World Scientific Publishing Company
Page : 621 pages
File Size : 49,91 MB
Release : 2013-05-06
Category : Technology & Engineering
ISBN : 1908977175
This is the second edition of the classic book An Introduction to Bioceramics which provides a comprehensive overview of all types of ceramic and glass materials that are used in medicine and dentistry. The enormous growth of the field of bioceramics is due to the recognition by the medical and dental community of the importance of bioactive materials to stimulate repair and regeneration of tissues. This edition includes 21 new chapters that document the science and especially the clinical applications of the new generation of bioceramics in the field of tissue regeneration and repair. Important socioeconomic factors influencing the economics and availability of new medical treatments are covered with updates on regulatory procedures for new biomaterials, methods for technology transfer and ethical issues.The book contains 42 chapters that offer the only comprehensive treatment of the science, technology and clinical applications of all types of bioceramic materials used in medicine and dentistry. Each chapter is written by leaders in their specialized fields and is a thorough review of the subject matter, unlike many conference proceedings. All chapters have been edited to reflect the same writing style, making the book an easy read. The completeness of treatment of all types of bioceramics and their clinical applications makes the book unique in the field and invaluable to all readers.
Author : Tadashi Kokubo
Publisher : Elsevier
Page : 785 pages
File Size : 38,13 MB
Release : 2008-03-25
Category : Science
ISBN : 1845694228
Bioceramics have been used very successfully within the human body for many years. They are commonly used in orthopaedic surgery and dentistry but they are potentially suitable for a wide range of important applications within the medical device industry. This important book reviews the range of bioceramics, their properties and range of clinical uses.Chapters in the first section of the book discusses issues of significance to a range of bioceramics such as their structure, mechanical properties and biological interactions. The second part reviews the fabrication, microstructure and properties of specific bioceramics and glasses, concentrating on the most promising materials. These include alumina and zirconia ceramics, bioactive glasses and bioactive glass-ceramics, calcium sulphate, tricalcium phosphate-based ceramics, hydroxyapatite, tricalcium phosphate/hydroxyapatite biphasic ceramics, si-substrated hydroxyapatite, calcium phosphate cement, calcium phosphate coating, titania-based materials, ceramic-polymer composites, dental ceramics and dental glass-ceramics. The final group of chapters reviews the clinical applications of bioceramics in joint replacement, bone grafts, tissue engineering and dentistry.Bioceramics and their clinical applications is written by leading academics from around the world and it provides an authoritative review of this highly active area of research. This book is a useful resource for biomaterials scientists and engineers, as well as for clinicians and the academic community. - Provides an authoritative review of this highly active area of research - Discusses issues of significance of a range of bioceramics such as their structure, mechanical properties and biological interactions - Reviews the clinical applications of bioceramics in joint replacement, bone grafts, tissue engineering and dentistry
Author : Changsheng Liu
Publisher : Springer
Page : 632 pages
File Size : 45,17 MB
Release : 2017-10-20
Category : Technology & Engineering
ISBN : 9811059756
This book presents a state-of-the-art review of the latest advances in developing calcium- phosphate bone cements and their applications. It covers the synthesis methods, characterization approaches, material modification and novel binders, as well as the fabrication technologies of calcium-phosphate-based biomaterials in regenerative medicine and their clinical applications. It also highlights methodologies for fabricating scaffolds, biofunctional surfaces/interfaces and subsequently modulating the host response to implantable/injectable materials, and integrates a series of discussions and insights into calcium-phosphate cements and constructs in bone regenerative medicine. As such, the book not only covers the fundamentals but also opens new avenues for meeting future challenges in research and clinical applications.
Author : Sabu Thomas
Publisher : Woodhead Publishing
Page : 500 pages
File Size : 14,74 MB
Release : 2018-02-16
Category : Technology & Engineering
ISBN : 0081022042
Fundamental Biomaterials: Ceramics provides current information on ceramics and their conversion from base materials to medical devices. Initial chapters review biomedical applications and types of ceramics, with subsequent sections focusing on the properties of ceramics, and on corrosion, degradation and wear of ceramic biomaterials. The book is ideal for researchers and professionals in the development stages of design, but is also helpful to medical researchers who need to understand and communicate the requirements of a biomaterial for a specific application. This title is the second in a three volume set, with each reviewing the most important and commonly used classes of biomaterials and providing comprehensive information on material properties, behavior, biocompatibility and applications. In addition, with the recent introduction of a number of interdisciplinary bio-related undergraduate and graduate programs, this book will be an appropriate reference volume for large number of students at undergraduate and post graduate levels - Provides current information on findings and developments of ceramics and their conversion from base materials to medical devices - Includes analyses of the types of ceramics and a discussion of a range of biomedical applications and essential properties, including information on corrosion, degradation and wear, and lifetime prediction of ceramic biomaterials - Explores both theoretical and practical aspects of ceramics in biomaterials
Author : Sergey V. Dorozhkin
Publisher : Nova Science Publishers
Page : 0 pages
File Size : 24,24 MB
Release : 2017
Category : Calcium phosphate
ISBN : 9781536118971
As the inorganic constituents of skeletons, dentine and the enamel of teeth in all vertebrates, as well as antlers of male deer, calcium orthophosphates (CaPO4) appear to be the key materials to sustain all life on Earth. Therefore, biologically relevant CaPO4 possess all the necessary features of the biomaterials, such as biocompatibility, bioactivity, bioresorbability, osteoconductivity, osteoinductivity, and appear to be non-toxic, non-inflammatory and non-immunogenic. In this book, the author presents current state-of-the-art applications of CaPO4 as bioceramics, deposits (coatings, films and layers) and in dentistry. Topics discussed include chemical composition and preparation, forming and shaping, sintering and firing for CaPO4-based bioceramics, chemical composition and preparation, pre- and post-deposition treatments for CaPO4-based deposits, followed by the detailed description of their major properties, biomedical applications and in vivo behavior. The detailed description of current CaPO4 applications in dentistry both for dental caries prevention and as various types of dental treatments is given in the last section of this book.
