Cancer Patients, Cancer Pathways


Book Description

Eleven essays by historians and sociologists examine cancer research and treatment as everyday practice in post-war Europe and North America. These are not stories of inevitable medical progress and obstacles overcome, but of historical contingencies, cultural differences, hope, and often disappointed expectations.




Signaling Pathways in Cancer Pathogenesis and Therapy


Book Description

In recent years, increasing evidence has suggested that abnormal activation of signaling pathways is a critical event in cancer pathogenesis. In particular, activation of these pathways can lead to inappropriate cellular survival, proliferation, pluripotency, invasion, metastasis, and angiogenesis. Thus, understanding the mechanisms by which signaling pathways become subverted in a cancer cell can provide insight into critical events in cancer pathogenesis. Furthermore, as our ability to target specific molecular interactions advances, we now have the ability to design small molecules, protein therapeutics, and other forms of targeted therapies. By focusing on the specific molecular abnormalities in a cancer cell, these agents hold the potential to be much more effective and much less toxic than current cytotoxic therapies.




Women's Cancers: Pathways to Healing


Book Description

The first goal of this book is to provide the patient with accurate information. The second goal is to show how a combination of "orthodox medicine" and complementary therapies can help people through their cancer diagnosis, treatment and follow up. Early chapters apply to all women diagnosed with cancer, followed by chapters for each specific site of disease. Then follow chapters on chemotherapy, radiotherapy, pain management, complementary therapies and spiritual approaches. The book incorporates a novel "4 cusp" approach, which enables women to explain to their families where they are in the process.




Stress Response Pathways in Cancer


Book Description

It is now established that dysregulated cell stress response pathways play a critical role in tumorigenesis, and a refined mechanistic understanding of this phenomenon at the molecular level promises to open new avenues for targeted therapeutic strategies that may benefit cancer patients in the near future. Coauthored by recognized leaders in cancer research from five continents, this novel book provides a comprehensive perspective on cell stress response pathways and therapeutic opportunities. Focusing on the role of genotoxic, proteotoxic, oxidative, metabolic, and inflammatory stress in tumorigenesis, the book is essential reading for students, basic researchers, and biomedical health care professionals interested in cancer and therapeutic development.










Unravelling Cancer Signaling Pathways: A Multidisciplinary Approach


Book Description

Unravelling the intricate cell signalling networks and their significance in cancer poses major intellectual challenge. Keeping this in mind, the book aims at understanding the mechanism of action of different proteins and their complexes in the cancer signalling pathways. Hence, the proposed book that comprises 20 chapters provides a comprehensive introduction on cell signalling, its alterations in cancer, molecules that have been popular targets as well as the ones that are emerging as targets. In addition, it discusses different forms of therapy that are coming up for its treatment. Other than that, a major portion of the book is focused on studying different disciplines at the interface of biology and other areas of science that are being used to understand cancer biology in depth.




Pathways to Progress


Book Description




Women's Cancers: Pathways to Healing


Book Description

The first goal of this book is to provide the patient with accurate information. The second goal is to show how a combination of "orthodox medicine" and complementary therapies can help people through their cancer diagnosis, treatment and follow up. Early chapters apply to all women diagnosed with cancer, followed by chapters for each specific site of disease. Then follow chapters on chemotherapy, radiotherapy, pain management, complementary therapies and spiritual approaches. The book incorporates a novel "4 cusp" approach, which enables women to explain to their families where they are in the process.




Cancer Care for the Whole Patient


Book Description

Cancer care today often provides state-of-the-science biomedical treatment, but fails to address the psychological and social (psychosocial) problems associated with the illness. This failure can compromise the effectiveness of health care and thereby adversely affect the health of cancer patients. Psychological and social problems created or exacerbated by cancer-including depression and other emotional problems; lack of information or skills needed to manage the illness; lack of transportation or other resources; and disruptions in work, school, and family life-cause additional suffering, weaken adherence to prescribed treatments, and threaten patients' return to health. Today, it is not possible to deliver high-quality cancer care without using existing approaches, tools, and resources to address patients' psychosocial health needs. All patients with cancer and their families should expect and receive cancer care that ensures the provision of appropriate psychosocial health services. Cancer Care for the Whole Patient recommends actions that oncology providers, health policy makers, educators, health insurers, health planners, researchers and research sponsors, and consumer advocates should undertake to ensure that this standard is met.