Cancer Screening and Genetics, An Issue of Surgical Clinics


Book Description

Cancer Screening and Genetics is reviewed extensively in this important Surgical Clinics of North America issue. Articles include: Cancer Genetics and Implications for Clinical Management; Epigenetics and Cancer; Screening and Early Detection of Cancer: Successes and Failures; Screening for Lung Cancer; Screening for Breast Cancer; Viral Hepatitis and Hepatocellular Cancer: How Should Patients Be Screened?; Screening for Pancreatic Cancer: Where Do We Stand?; Hereditary Colorectal Cancer: Genetics and Screening; Personalized Approach to Gastrointestinal Cancers; Screening for Colorectal Cancer; Screening for Prostate Cancer: Why the Controversy?; Gastric Cancer: East versus West—Is screening and early detection the difference?; and more!




Genetics for Surgeons


Book Description

Morrison (human genetics, University of Ulster, UK) and Spence (biomedical science, University of Ulster, UK) offer an accessible reference on the genetic disorders that surgeons can expect to meet in general surgical practice. Written in non-technical language, with a glossary, list of abbreviations, and color and b&w photos and medical images, the book supplies an introduction to the nomenclature and technology of molecular biology, and will be a useful starting point for those who wish to extend their knowledge. Annotation :2005 Book News, Inc., Portland, OR (booknews.com).




Genetics of Colorectal Cancer


Book Description

Genetic susceptibility refers to how variations in a person’s genes increase or decrease his or her susceptibility to environmental factors, such as chemicals, radiation and lifestyle (diet and smoking). This volume will explore the latest findings in the area of genetic susceptibility to gastrointestinal cancers, focusing on molecular epidemiology, DNA repair, and gene-environment interactions to identify factors that affect the incidence of GI cancers. Topics will include germline susceptibility, including Mendelian patterns of inheritance and gene-environment interactions that lead to cancer etiology.




Surgical Research


Book Description

Contributors. -- Foreword. -- Preface. -- Getting Started. -- Assessing Available Information. -- Organizing and Preliminary Planning for Surgical Research -- Writing a Protocol: Animals, Humans, and Use of Biologic, Chemical, and Radiologic Agents. -- Grantsmanship. -- Informed Consent and the Protection of Human Research Subjects: Historical Perspectives and Guide to Current United States Regulations. -- Animal Care and Maintenance. -- Funding Strategies and Agencies: Academic-Industrial Relationships; Intellectual Property. -- Statistical Considerations. -- Use of Nonexperimental Studies to Evaluate Surgical Procedures and Other Interventions: The Challenge of Risk Adjustment. -- Measuring Surgical Outcomes. -- Design of Clinical Trials. -- Using Administrative Data for Clinical Research. -- Research in the Intensive Care Unit: Ethical and Methodological Issues. -- Research in the Operating Room. -- Effects of Age and Gender. -- Strategies, Principles, and Techniques Using Transgeni ...




Clinical Cancer Genetics


Book Description

Written by a world-recognized leader in this emerging field, Clinical Cancer Genetics provides an updated and expanded treatment of Kenneth Offit's seminal text on the clinical management associated with syndromes of cancer predisposition, with a thorough review of the relevant molecular genetics. This second edition features new coverage of pharmacogenetics, gene therapy trials, high throughput genotyping, and microarrays and includes a new focus on epigenetic events in carcinogenesis within background chapter on cancer genetics. Expanded coverage highlights more uncommon and rare cancer predisposition syndromes.




Management of Breast Cancer, An Issue of Surgical Clinics, E-Book


Book Description

This issue of Surgical Clinics of North America focuses on Management of Breast Cancer, and is edited by Dr. Catherine C. Parker. Articles will include: Screening mammography: recommendations and controversies; High risk breast cancer patients: genetics and indications for prophylactic mastectomy; Incorporation of biologic factors into breast cancer staging; Impact of advancing technology on diagnosis and treatment of breast cancer; Ductal Carcinoma In Situ; Management of the axilla in the patient with breast cancer; Definition and management of positive margins for invasive breast cancer; Neoadjuvant chemotherapy for HER2-positive and triple negative breast cancer; Inflammatory breast cancer; Role of radiation in breast cancer; Breast cancer in the elderly; Evolution of operative technique for mastectomy; Breast reconstruction; Role of operative management in Stage IV breast cancer; Sarcomas of the breast; and more!




Perioperative Management, An Issue of Surgical Clinics of North America


Book Description

Perioperative Management is reviewed extensively in this important Surgical Clinics of North America issue. Articles include: Cardiac risk stratification and protection; Prevention of pulmonary complications; Perioperative nutrition; Prophylactic antibiotics and prevention of post-operative infections; DVT and VTE prophylaxis; Post-operative pain control and sedation; End points of resuscitation; Optimal glucose management in the perioperative period; Essentials of sepsis management; Transfusion and management of surgical patients with hematologic disorders; Perioperative management of the obese patient; Perioperative management of the elderly patient; Perioperative management in the patient with substance abuse; Management of the pregnant patient undergoing general surgical procedures; Advanced directives, living wills and futility; and more!




Inflammatory Bowel Disease, An Issue of Surgical Clinics


Book Description

Inflammatory Bowel Disease is reviewed extensively in this important Surgical Clinics of North America issue. Articles include: Inflammatory Bowel Disease: Historical Perspective, Epidemiology and Risk Factors; Diagnostic Modalities for Inflammatory Bowel Disease: Serologic Markers and Endoscopy; Diagnostic Modalities for Inflammatory Bowel Disease: Radiologic Imaging; Medical Therapy for Inflammatory Bowel Disease; Crohn's Disease of the Foregut and Small Intestine; Crohn's Disease of the Colon, Rectum and Anus; Indications and Options for Surgery in Ulcerative Colitis; Challenges in the Medical and Surgical Management of Chronic Inflammatory Bowel Disease; Extraintestinal Manifestations of Inflammatory Bowel Disease; Colorectal Neoplasia and Inflammatory Bowel Disease; Nutritional Support of the Inflammatory Bowel Disease Patient; Psychosocial Support of the Inflammatory Bowel Disease Patient; Genetics and Pathogenesis of Inflammatory Bowel Disease; and more!




The Role of Genetic Testing in Surgical Oncology, An Issue of Surgical Oncology Clinics of North America


Book Description

This issue of Surgical Oncology Clinics of North America, edited by Thomas Weber, MD, is devoted to Genetic Testing in Surgical Oncology. Articles in this issue include: The Critical Importance of Timely Genetic Testing; Securing and Documenting Cancer Family History in the Age of the Electronic Medical Record; Cancer Family Registries: Vital Tools for Patient Management and Cancer Genetics Translational Research; The Genetics of Breast Cancer; The Genetics of Colorectal Cancer: HNPCC, FAP MYH, and Hamartomatous Syndromes Including Peutz-Jeghers and Jevenile Polyposis; Hereditary Gastric Cancer Syndromes; Hereditary Pancreatic Cancer Syndromes; Hereditary Melanoma: Genetics and Multidisciplinary Management; Multiple Endocrine Neoplasia: Genetics and Clinical Management; Sequence Variants of Uncertain Significance (VUS): What To Do When Genetic Testing Results Are Not Definitive; Confidentiality and the Risk of Genetic Discrimination: What Surgeons Need to Know; and A Certified Genetic Counselor: A Crucial Clinical Resource in the Management of Patients with Suspected Hereditary Solid Tumor Syndromes.




Surgeon's Role in Multidisciplinary Breast Management, An Issue of Surgical Clinics


Book Description

A comprehensive and important issue devoted to multidisciplinary breast management! Topics will include neoadjuvant chemotherapy, pathology of invasive breast disease, management of high risk lesions, genetic predisposition syndromes, radiation therapy, surgical management of the breast–mastectomy and breast conservation, management of the axilla, management of ductal carcinoma in situ, breast reconstruction, adjuvant therapy, screening, imaging, and image guided biopsy techniques for breast cancer, benign breast disease, and much more!