Author : Bryan Cullen
Publisher : Oxford University Press
Page : 220 pages
File Size : 14,43 MB
Release : 1993
Category : Gene Expression Regulation.
ISBN : 9780199633821
The first book to specifically cover the molecular biology of retroviruses - of immense importance since the high profile of HIV. International contributors provide detailed reviews of the latest knowledge. An excellent text for both medical and non-medical researchers, it also serves as an illuminating introduction for scientists active in other areas.
Author : John A.T. Young
Publisher : Springer Science & Business Media
Page : 250 pages
File Size : 35,29 MB
Release : 2012-12-06
Category : Medical
ISBN : 364219012X
The articles in this volume provide a comprehensive overview of our current understanding of the roles played by cellular factors in the early steps of retroviral replication. A better understanding of these functions will provide critical new insights into retrovirus-host cell interactions and is likely to prove useful for the future development of effective antiretroviral therapies.
Author : Thomas J. Hope
Publisher :
Page : pages
File Size : 47,96 MB
Release :
Category : AIDS (Disease)
ISBN : 9781461496106
Author : John A T Young
Publisher :
Page : 256 pages
File Size : 25,52 MB
Release : 2003-07-23
Category :
ISBN : 9783642190131
Author : Nouri Neamati
Publisher : John Wiley & Sons
Page : 710 pages
File Size : 16,89 MB
Release : 2011-08-10
Category : Science
ISBN : 1118015363
This book comprehensively covers the mechanisms of action and inhibitor design for HIV-1 integrase. It serves as a resource for scientists facing challenging drug design issues and researchers in antiviral drug discovery. Despite numerous review articles and isolated book chapters dealing with HIV-1 integrase, there has not been a single source for those working to devise anti-AIDS drugs against this promising target. But this book fills that gap and offers a valuable introduction to the field for the interdisciplinary scientists who will need to work together to design drugs that target HIV-1 integrase.
Author : Phoebe A. Rice
Publisher : Royal Society of Chemistry
Page : 417 pages
File Size : 40,92 MB
Release : 2008-05-22
Category : Science
ISBN : 0854042725
This book provides both in-depth background and up-to-date information in this area. The chapters are organized by general themes and principles, written by experts who illustrate topics with current findings. Topics covered include: - the role of ions and hydration in protein-nucleic acid interactions - transcription factors and combinatorial specificity - indirect readout of DNA sequence - single-stranded nucleic acid binding proteins - nucleic acid junctions and proteins, - RNA protein recognition - recognition of DNA damage. It will be a key reference for both advanced students and established scientists wishing to broaden their horizons.
Author : Lawrence C. Kuo
Publisher : Gulf Professional Publishing
Page : 494 pages
File Size : 31,58 MB
Release : 1994-09-22
Category : Medical
ISBN : 9780121821425
Methods included in this volume apply to the expression and characterization of retroviral proteases and their inhibitor/substrate design.
Author : Jennifer Louten
Publisher : Academic Press
Page : 412 pages
File Size : 15,71 MB
Release : 2022-05-28
Category : Science
ISBN : 0323914926
Essential Human Virology, Second Edition focuses on the structure and classification of viruses, virus transmission and virus replication strategies based upon type of viral nucleic acid. Several chapters focus on notable and recognizable viruses and the diseases caused by them, including influenza, HIV, hepatitis viruses, poliovirus, herpesviruses and emerging and dangerous viruses. Additionally, how viruses cause disease (pathogenesis) is highlighted, along with discussions on immune response to viruses, vaccines, anti-viral drugs, gene therapy, the beneficial uses of viruses, research laboratory assays and viral diagnosis assays. Fully revised and updated with new chapters on coronaviruses, nonliving infectious agents, and notable non-human viruses, the book provides students with a solid foundation in virology. - Focuses on human diseases and the cellular pathology that viruses cause - Highlights current and cutting-edge technology and associated issues - Presents real case studies and current news highlights in each chapter - Features dynamic illustrations, chapter assessment questions, key terms, and a summary of concepts, as well as an instructor website with lecture slides, a test bank and recommended activities - Updated and revised, with new chapters on coronaviruses, nonliving infectious agents, and notable non-human viruses
Author : Reinhard Kurth
Publisher : Caister Academic Press Limited
Page : 0 pages
File Size : 29,40 MB
Release : 2010
Category : Science
ISBN : 9781904455554
Leading scientists in the field review the genomics, molecular biology and pathogenesis of these important viruses, comprehensively covering all the recent advances.
Author : Guido Silvestri
Publisher : Springer
Page : 253 pages
File Size : 43,13 MB
Release : 2018-10-11
Category : Medical
ISBN : 303002816X
This volume summarizes recent advances in understanding the mechanisms of HIV-1 latency, in characterizing residual viral reservoirs, and in developing targeted interventions to reduce HIV-1 persistence during antiretroviral therapy. Specific chapters address the molecular mechanisms that govern and regulate HIV-1 transcription and latency; assays and technical approaches to quantify viral reservoirs in humans and animal models; the complex interchange between viral reservoirs and the host immune system; computational strategies to model viral reservoir dynamics; and the development of therapeutic approaches that target viral reservoir cells. With contributions from an interdisciplinary group of investigators that cover a broad spectrum of subjects, from molecular virology to proof-of-principle clinical trials, this book is a valuable resource for basic scientists, translational investigators, infectious-disease physicians, individuals living with HIV/AIDS and the general public.
