Challenges in Pediatric Kidney Transplantation


Book Description

This book provides a comprehensive overview of the unique challenges inherent in pediatric kidney transplantation. The text reviews the problems faced during each stage of the kidney transplantation process, including the occurrence of infections during the pre-transplant stage, surgical challenges during the actual transplantation, and medication issues during the post-transplant stage. The book also features high-yield case presentations of typical pediatric transplant scenarios, from the pre-transplant management of a child with CAKUT to the evaluation and treatment of antibody mediated rejection in children. Written by experts in the field, Challenges in Pediatric Kidney Transplantation: A Practical Guide is a valuable resource for clinicians, practitioners, and trainees who manage or are interested in this challenging group of patients.




Pediatric Renal Transplantation


Book Description

A detailed, contributed reference offering broad coverage of renal transplantation in children. Diagnosis, the patient's medical management, operative methods, surgical and medical complications, donor selection, immunosuppression, late effects on growth and development and psychosocial factors are among the topics discussed. Features a chapter on how to set up and manage a pediatric renal transplant program.




Ethical Issues in Pediatric Organ Transplantation


Book Description

This book offers a theoretical and practical overview of the specific ethical and legal issues in pediatric organ transplantation. Written by a team of leading experts, Ethical Issues in Pediatric Organ Transplantation addresses those difficult ethical questions concerning clinical, organizational, legal and policy issues including donor, recipient and allocation issues. Challenging topics, including children as donors, donation after cardiac death, misattributed paternity, familial conflicts of interest, developmental disability as a listing criteria, small bowel transplant, and considerations in navigating the media are discussed. It serves as a fundamental handbook and resource for pediatricians, transplant health care professionals, trainees, graduate students, scholars, practitioners of bioethics and health policy makers.




Pediatric Renal Transplantation


Book Description

The role of immunosuppression is essential to maintain the integrity of a renal transplant by preventing acute rejection. Among adult patients with solid organ transplants, standard immunosuppression does not vary among the major transplant centres in the USA and Europe, and consists of corticosteroids, calcineurin inhibitors and mycophenolic acid. However, children with renal transplants are more susceptible than adults to suffer adverse events related to this standard protocol, including short stature, nephrotoxicity, lymph proliferative disease and infections. For this reason, paediatric nephrologists have explored alternatives to standard immunosuppression while still maintaining acceptable graft outcomes. This book will explore this theme, which will include several chapters that present alternative immunosuppression protocol, in addition to other chapters that address challenging and controversial issues in paediatric renal transplantation. The first three chapters will describe immunosuppression protocols which may have specific benefits in children with renal allografts compared to standard regimens in adults. This includes the use of steroid-avoidance, which obviates many of the problems associated with corticosteroid use in children especially short stature and obesity. Secondly, the mTOR inhibitor Sirolimus is thoroughly discussed, including the potential benefits of this agent because of its lack of nephrotoxicity and possible anti-neoplastic properties. Lastly, induction therapy with Alemtuzumab is described, including recent studies that suggest that this agent may have definite benefits in children compared to standard induction with anti-thymocyte globulin.







Kidney Transplantation


Book Description

This fifth edition of KIDNEY TRANSPLANTATION remains the most comprehensive and definitive text on all aspects of renal transplantation as well as the psychological and ethical issues involved. Almost every chapter has been revised or rewritten by new authors, to incorporate the most essential and up-to-date information.




Challenges and Controversies in Kidney Transplantation


Book Description

Challenges and Controversies in Kidney Transplantation highlights the most up-to-date strategies for successfully managing high-risk kidney transplant recipients, as well as detailed, innovative strategies to increase transplant opportunities for patients requiring kidney transplantation. The book is divided into two major sections; firstly, Maximizing Transplant Opportunities, and second, Considerations for Unique/High Risk Patient Populations focusing on management of select patient populations, such as children, the elderly, HIV, Hepatitis C positive patents, highly sensitized patients, and patients who develop post-transplant polyomavirus nephropathy. Surgical topics include Laparoendoscopic Single Site and Robotic Donor Nephrectomy as minimally invasive surgical procedures to increase living donation, and the use of Paediatric Donor Kidneys in deceased donor kidney transplantation. In addition, Challenges and Controversies in Kidney Transplantation also features discussion on the most difficult clinical management issues confronting Kidney Transplantation today, making it a relevant and essential reference for nephrologists, neurologists and residents. Key Points Concise and comprehensive guide to problems associated with kidney transplantation Full colour illustrations Authored by Sandip Kapur, Professor of Surgery at Weill Medical College – Cornell University, USA




Kidney Transplantation


Book Description

This e-book is an overview of recent advances in the realm of kidney transplantation. The volume discusses developments in surgical procedures while presenting a perspective on possibilities for kidney transplant research in the future. The e-book is a c




Kidney Transplantation


Book Description

Updated to reflect today’s practice guidelines, the new edition of this comprehensive text remains the definitive resource on all aspects of renal transplantation, including immunological, pathological, psychological and ethical considerations. It examines evaluation, management, and procurement of living and deceased donor kidneys, the selection of suitable recipients, interpretation of graft dysfunction, and expected survival based upon a large database of information. There are comprehensive chapters on pediatric renal transplantation and on renal transplantation in the developing world. Extensive tables and figures and comprehensive lists of references with each chapter enhance its value to the transplant team. A multidisciplinary approach from internationally renowned contributors from around the world-many new to this edition-offers practice-applicable guidance for all members of the transplant team, with coverage encompassing applied science, clinical information, and surgical procedures. This 6th edition remains the balanced reference you need to stay apprised of issues important to successful kidney transplantation. Provides a comprehensive description of surgical techniques, immunosuppressive methods, outcomes, risks, and medical considerations related to kidney transplantation, both in adults and children, in one convenient reference. Presents more than 335 superb illustrations-50 in full color-that demonstrate key concepts and nuances of techniques. Features a multidisciplinary approach from contributors from around the world-many new to this edition-offers practice-applicable guidance for all members of the transplant team, with coverage encompassing applied science, clinical information, and surgical procedures. Offers evidence-based decision making advice in renal transplantation-supported by a wealth of data in chapters written by internationally recognized experts-to help you make the most informed clinical decisions. Offers new tables and figures as well as revised and updated chapters that report new data and present current practice guidelines. Features a new chapter on transplantation in the sensitized patient to assist you with transplant cases that present unique challenges. Describes the latest preclinical and clinical immunosuppressive strategies, to help you see the link between clinical issues and the basic sciences. Offers tissue typing methodology updates, equipping you with the newest methods of assessing immune responses to the kidney. Features a new chapter on chronic allograft nephropathy.