Chico's Challenge


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Set in Wyoming, Chico's Challenge follows a young buckskin quarter horse who is trade to Sierra, a teen who works her father's ranch and dreams of becoming a cutting horse champion. Chico seems to have the makings of a great cow horse, but...he has never seen a cow in his life! Can he and Sierra, both novices, learn to work together as a team?




Challenges in Protein Product Development


Book Description

In this volume, the authors discuss the many significant challenges currently faced in biotechnology dosage form development, providing guidance, shared experience and thoughtful reflection on how best to address these potential concerns. As the field of therapeutic recombinant therapeutic proteins enters its fourth decade and the market for biopharmaceuticals becomes increasingly competitive, companies are increasingly dedicating resources to develop innovative biopharmaceuticals to address unmet medical needs. Often, the pharmaceutical development scientist is encountering challenging pharmaceutical properties of a given protein or by the demands placed on the product by stability, manufacturing and preclinical or clinical expectations, as well as the evolving regulatory expectations and landscape. Further, there have been new findings that require close assessment, as for example those related to excipient quality, processing, viscosity and device compatibility and administration, solubility and opalescence and container-closure selection. The literature varies widely in its discussion of these critical elements and consensus does not exist. This topic is receiving a great deal of attention within the biotechnology industry as well as with academic researchers and regulatory agencies globally. Therefore, this book is of interest for business leaders, researchers, formulation and process development scientists, analytical scientists, QA and QC officers, regulatory staff, manufacturing leaders and regulators active in the pharmaceutical and biotech industry, and expert reviewers in regulatory agencies.




FCC Record


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Special Publication


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Hourly Precipitation Data


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Challenging Lesbian Norms


Book Description

What constitutes lesbian identity? The term homonormativity describes current prevailing idealized assumptions about lesbian identity. This concept, however, marginalizes subgroups within the greater lesbian population. Challenging Lesbian Norms: Intersex, Transgender, Intersectional, and Queer Perspectives dynamically confronts homonormativity in lesbian communities by presenting expert multidisciplinary discussion about what is a definable lesbian identity. This text sensitively explores difficult issues about gender policing and the viewpoints in lesbian communities that hold that transgender, intersectional, and queer individuals are considered to have 'false consciousness.' Consequences of lesbian normativity, both for lesbian communities and for marginalized groups are examined through literary criticism, lesbian, feminist, and queer theories, corporeal philosophy, film, television, cultural criticism, personal narratives, public health, and field research. The issue of the authenticity of lesbian identity causes rifts between some lesbian communities and the groups that strive to be included, yet are still marginalized. Challenging Lesbian Norms directly exposes practices and beliefs within lesbian communities that lead to the assumption of the prototypical lesbian. The book courageously reveals the similarities of lesbian normative stances with other views such as Christian conservative rhetoric, and reviews the health consequences of being marginalized within the lesbian communities. This text actively challenges the foundational notion within lesbian communities that a stable, immutable lesbian sex exists. Topics in Challenging Lesbian Norms include: human physiology, the flexibility of sexuality, and biologic determinism marginalization within lesbian communities transexualism and Lesbian Theory gender and sexual identity construction, partnering practices, and issues involving queer-identified youth demystification of the gay vibe from a femme queer woman’s perspective lesbian feminism, gender policing, and casting butch, FTM, and transgendered subjectivities as “false conciousness” representations of lesbians in television movies Native-American “two-spirit” women teaching transgender, and its transformative effect identity modeling inclusion of transgender and intersex individuals within the lesbian communities transgender characters in film Latina lesbians and mental health Challenging Lesbian Norms is stimulating, eye-opening reading that is perfect for activists, educators and students in LGBT and women’s studies, and public health professionals.




50 Spanish Coffee Breaks


Book Description

Transform your down time into 'do time'. The most successful language learners create a habit of studying on a regular basis. 50 Spanish Coffee Breaks makes it easy to master a simple routine of improving your Spanish by effortlessly integrating it with your calming daily ritual -from a 5-minute espresso to a 15-minute latte. Organised by 5, 10 and 15 minutes, these 50 varied and lively activities - from anagrams and idiom challenges to recipes and quotations - are created for high-beginner to intermediate adult and young-adult learners and designed to keep you motivated while building your skills in key areas. · Reading comprehension · Writing skills · Grammar confidence · Translation abilities · Vocabulary expansion · Cultural awareness By practising Spanish in a fun and relaxed way in the time you have, you will stay on track to achieve your language-learning aspirations. So, pick up your preferred brew and this practical book, and make learning the most pleasant and productive part of your busy day. The Spanish used in this book includes a variety of sources and contexts including both Peninsular Spanish and Latin American Spanish, making the book a valuable tool for learners of both. For 15 years Coffee Break Languages has helped make it possible for millions of people to learn a language in a way that fits into their everyday life: whether that's while walking the dog, at the gym, or on their coffee break! Teach Yourself has collaborated with Coffee Break Languages to bring their brilliant method to a wider audience by producing their first-ever printed product. All the activities are written by long-time teachers of the language in Coffee Break's characteristically friendly and conversational style. It's the perfect complement to your studies. The activities are levelled for high-beginner to low-intermediate learners: CEFR A2-B1 and ACTFL Intermediate-low/mid




Climatological Data


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