Cingulate Neurobiology and Disease


Book Description

One of the major neuroscience publications of the past few years, Cingulate Neurobiology and Disease presents the definitive review of the cingulate cortex, explaining its critical role in a host of diseases and illnesses.







The Brain and Behavior


Book Description

New edition building on the success of previous one. Retains core aim of providing an accessible introduction to behavioral neuroanatomy.




Cingulate Cortex


Book Description

Cingulate Cortex, Volume 166 summarizes research on the cingulate cortex, including its structure and function in health and how it is compromised in disease or trauma. Chapters discuss the cingulate organization by region and area, cover its function in consciousness, attention, social cognition and spatial orientation, review neurological disorders with cingulate involvement, including neurodegenerative disorders, movement disorders, Parkinson’s, ADHD, Cognitive impairment, Palsy, Tourette’s Syndrome, chronic pain, seizures, and more. Final sections discuss the relationship between the cingulate cortex, stress and psychiatric disorders. Coverage here includes PTSD, anxiety, depression, and evidence-based treatment for same. Identifies the structure and function of all areas and regions of the cingulate cortex Discusses its role in sensory-motor, cognitive and emotional processing Covers cingulate-mediated neurological and psychiatric disorders Supplies evidence-based treatment for cingulate mediated disorders




Motivation


Book Description

Motivation: Theory, Neurobiology and Applications is inspired by a question central to health care professionals, teachers, parents, and coaches alike, "How can an individual be motivated to perform a given activity or training?" It presents novel measurements of motivation developed in psychology and economics, recent insights into the neurobiology of motivation, and current research on applications designed to boost motivation in neurorehabilitation, education, and sports. In addition, tactics on how to connect these different research and knowledge fields within a common (theoretical) framework of motivation is discussed. Thus, in short, the book provides an integrative, interdisciplinary, up-to-date accounting on the neurobiology of motivation and how it might be boosted. Provides an integration of the neurosciences, their clinical challenges, and applicable research Includes both an interdisciplinary and integrative nature Contains a broad array of subject matter that will be of interest to a large target audience Presents contributions from experts in their respective fields




The Neuropathology of Huntington’s Disease: Classical Findings, Recent Developments and Correlation to Functional Neuroanatomy


Book Description

This monograph describes the progress in neuropathological HD research made during the last century, the neuropathological hallmarks of HD and their pathogenic relevance. Starting with the initial descriptions of the progressive degeneration of the striatum as one of the key events in HD, the worldwide practiced Vonsattel HD grading system of striatal neurodegeneration will be outlined. Correlating neuropathological data with results on the functional neuroanatomy of the human brain, subsequent chapters will highlight recent HD findings: the neuronal loss in the cerebral neo-and allocortex, the neurodegeneration of select thalamic nuclei, the affection of the cerebellar cortex and nuclei, the involvement of select brainstem nuclei, as well as the pathophysiological relevance of these pathologies for the clinical picture of HD. Finally, the potential pathophysiological role of neuronal huntingtin aggregations and the most important and enduring challenges of neuropathological HD research are discussed.




The Neurobiology of Attachment-Focused Therapy: Enhancing Connection & Trust in the Treatment of Children & Adolescents (Norton Series on Interpersonal Neurobiology)


Book Description

Uniting attachment-focused therapy and neurobiology to help distrustful and traumatized children revive a sense of trust and connection. How can therapists and caregivers help maltreated children recover what they were born with: the potential to experience the safety, comfort, and joy of having trustworthy, loving adults in their lives? This groundbreaking book explores, for the first time, how the attachment-focused family therapy model can respond to this question at a neural level. It is a rich, accessible investigation of the brain science of early childhood and developmental trauma. Each chapter offers clinicians new insights—and powerful new methods—to help neglected and insecurely attached children regain a sense of safety and security with caring adults. Throughout, vibrant clinical vignettes drawn from the authors' own experience illustrate how informed clinical processes can promote positive change. Authors Baylin and Hughes have collaborated for many years on the treatment of maltreated children and their caregivers. Both experienced psychologists, their shared project has bee the development of the science-based model of attachment-focused therapy in this book—a model that links clinical interventions to the crucial underlying processes of trust, mistrust, and trust building—helping children learn to trust caregivers and caregivers to be the "trust builders" these children need. The book begins by explaining the neurobiology of blocked trust, using the latest social neuroscience to show how the child's early development gets channeled into a core strategy of defensive living. Subsequent chapters address, among other valuable subjects, how new research on behavioral epigenetics has shown ways that highly stressful early life experiences affect brain development through patterns of gene expression, adapting the child's brain for mistrust rather than trust, and what it means for treatment approaches. Finally, readers will learn what goes on in the child's brain during attachment-focused therapy, honing in on the dyadic processes of adult-child interaction that seem to embody the core "mechanisms of change": elements of attachment-focused interventions that target the child's defensive brain, calm this system, and reopen the child's potential to learn from new experiences with caring adults, and that it is safe to depend upon them. If trust is to develop and care is to be restored, clinicians need to know what prevents the development of trust in the first place, particularly when a child is living in an environment of good care for a long period of time. What do abuse and neglect do to the development of children's brains that makes it so difficult for them to trust adults who are so different from those who hurt them? This book presents a brain-based understanding that professionals can apply to answering these questions and encouraging the development of healthy trust.




Neurobiology of Sensation and Reward


Book Description

Synthesizing coverage of sensation and reward into a comprehensive systems overview, Neurobiology of Sensation and Reward presents a cutting-edge and multidisciplinary approach to the interplay of sensory and reward processing in the brain. While over the past 70 years these areas have drifted apart, this book makes a case for reuniting sensation a




Neurobiology and Treatment of Traumatic Dissociation


Book Description

Encompassing the contributions of expert clinicians and researchers in the area of traumatic stress and dissociation, this volume is the first to integrate current neuroscience research regarding traumatic dissociation with several cutting-edge approaches to treatment, providing a comprehensive, neurobiologically based treatment approach. The text discusses current neuroscientific research regarding traumatic stress and dissociation that includes attachment, affective neuroscience, polyvagal theory, structural dissociation, and information processing theory, yielding a comprehensive model that guides treatment and clinical interventions for traumatic dissociation. It then integrates this model with stage-oriented treatment and current therapeutic interventions, including EMDR, somatic and body psychotherapy approaches, Ego State Therapy, and adjunctive pharmacological interventions. Readers are given hands-on practical guidance regarding clinical decision making, enabling them to make sound choices about interventions that will facilitate optimal treatment outcomes. Key Features: Provides a broad-based treatment approach to traumatic stress syndromes and dissociation Offers accessible current research in the basic neurosciences relevant to our understanding of attachment, traumatic stress, and dissociation Includes practical suggestions for integrating EMDR, somatic, and body psychotherapy approaches with Ego State Therapy and adjunctive pharmacological interventions Integrates concepts from the affective and cognitive neurosciences and the study of consciousness Presents a comprehensive neurobiological model that accounts for the therapeutic effects of both somatic therapies and EMDR, as well as adjunctive pharmacological interventions




The Cognitive-Emotional Brain


Book Description

A study that goes beyond the debate over functional specialization to describe the ways that emotion and cognition interact and are integrated in the brain. The idea that a specific brain circuit constitutes the emotional brain (and its corollary, that cognition resides elsewhere) shaped thinking about emotion and the brain for many years. Recent behavioral, neuropsychological, neuroanatomy, and neuroimaging research, however, suggests that emotion interacts with cognition in the brain. In this book, Luiz Pessoa moves beyond the debate over functional specialization, describing the many ways that emotion and cognition interact and are integrated in the brain. The amygdala is often viewed as the quintessential emotional region of the brain, but Pessoa reviews findings revealing that many of its functions contribute to attention and decision making, critical components of cognitive functions. He counters the idea of a subcortical pathway to the amygdala for affective visual stimuli with an alternate framework, the multiple waves model. Citing research on reward and motivation, Pessoa also proposes the dual competition model, which explains emotional and motivational processing in terms of their influence on competition processes at both perceptual and executive function levels. He considers the broader issue of structure-function mappings, and examines anatomical features of several regions often associated with emotional processing, highlighting their connectivity properties. As new theoretical frameworks of distributed processing evolve, Pessoa concludes, a truly dynamic network view of the brain will emerge, in which "emotion" and "cognition" may be used as labels in the context of certain behaviors, but will not map cleanly into compartmentalized pieces of the brain.