Clinical Enzymology; Enzymes in Pathogenesis, Diagnosis, and Therapy
Author : Rudolf Abderhalden
Publisher :
Page : 470 pages
File Size : 12,45 MB
Release : 1961
Category : Enzymes
ISBN :
Author : Rudolf Abderhalden
Publisher :
Page : 470 pages
File Size : 12,45 MB
Release : 1961
Category : Enzymes
ISBN :
Author : Rudolph ABDERHALDEN
Publisher :
Page : 448 pages
File Size : 40,25 MB
Release : 1961
Category :
ISBN :
Author : D.M. Goldberg
Publisher :
Page : 162 pages
File Size : 24,29 MB
Release : 1987
Category :
ISBN :
Author : David M. Goldberg
Publisher : S. Karger AG (Switzerland)
Page : 200 pages
File Size : 49,91 MB
Release : 1987
Category : Medical
ISBN :
Author : International Society for Clinical Enzymology
Publisher :
Page : 162 pages
File Size : 14,8 MB
Release : 1987
Category :
ISBN : 9783805543446
Author :
Publisher :
Page : 162 pages
File Size : 40,39 MB
Release : 1987
Category :
ISBN :
Author : Nikolaos Labrou
Publisher : Springer Nature
Page : 388 pages
File Size : 46,37 MB
Release : 2019-09-03
Category : Science
ISBN : 981137709X
Therapeutic enzymes exhibit fascinating features and opportunities, and represent a significant and promising subcategory of modern biopharmaceuticals for the treatment of several severe diseases. Research and drug developments efforts and the advancements in biotechnology over the past twenty years have greatly assisted the introduction of efficient and safe enzyme-based therapies for a range of both rare and common disorders. The introduction and regulatory approval of twenty different recombinant enzymes has enabled effective enzyme-replacement therapy. This volume aims to overview these therapeutic enzymes, focusing in particular on more recently approved enzymes produced by recombinant DNA technology. This volume is composed of four sections. Section 1 provides an overview of the production process and biochemical characterization of therapeutic enzymes, while Section 2 focuses upon the engineering strategies and delivery methods of therapeutic enzymes. Section 3 highlights the clinical applications of approved therapeutic enzymes, including aspects on their structure, indications and mechanisms of action. Together with information on these mechanisms, safety and immunogenicity issues and various adverse events of the recombinant enzymes used for therapy are discussed. Section 4, provides discussion on the prospective and future developments of new therapeutic enzymes. This book is aimed at academics, researchers and students undertaking advanced undergraduate/postgraduate programs in the biopharmaceutical/biotechnology area who wish to gain a comprehensive understanding of enzyme-based therapeutic molecules.
Author : Rudolf Abderhalden
Publisher :
Page : 472 pages
File Size : 37,39 MB
Release : 1961
Category : Enzymes
ISBN :
Author : Dermot Patrick Mullan
Publisher :
Page : 264 pages
File Size : 30,71 MB
Release : 1969
Category : Clinical enzymology
ISBN :
Studies in Clinical Enzymology presents a critical review of the nature and diagnostic value of enzymes. It discusses the characteristics of iso-enzymes; the enzymes changes in myocardial infarction, cardiomyopathies, and non-ischemic heart failure; and the characteristics of enzymes studied in African heart disease. Some of the topics covered in the book are the simple enzyme kinetics; classification of enzymes; description of activators and co-enzymes; mechanics of enzyme inhibition; effects of drugs in enzyme reactions; function of the cell membrane; distribution of enzymes; mechanism of en ...
Author : John Alfred Lott
Publisher :
Page : 300 pages
File Size : 32,20 MB
Release : 1986
Category : Science
ISBN :