Composite Tissue Allograft


Book Description

The first textbook of its kind dealing with composite tissue allograft and allograft transplantation, provides an excellent overview on the subject. It provides a clear description of the current status of the transplant of every composite tissue allograft already performed and others which are still at the basic experimental level.The editors of the book, who also contribute chapters in their expertise, are world renowned surgeons. This book opens with an introductory chapter on the history of this type of transplantation and then details the clinical experience in each graft such as hand, larynx, face, uterus and the related histopathology, immunosuppression and immunomodulation.A multidisciplinary and comprehensive presentation of the various aspects of this new area of transplantation will allow the reader to understand the complexity and the challenges of composite tissue transplantation. A number of important topics are analyzed and discussed in detail, such as the ethical, medicolegal, psychological and immunological implications. New rehabilitation techniques and strategies, together with innovative tools for the functional evaluation of the transplanted parts, are highlighted. A section on the experimental work underlines what lies ahead of us./a




Transplantation of Composite Tissue Allografts


Book Description

This brilliant synthesis summarizes all of the recent accomplishments – as well as the ongoing research – in the field of composite tissue transplantation. It includes sections on hand transplantation and vascularized bone marrow transplantation. The volume focuses on immunology and the biotechnology/bioengineering aspects of transplantation surgery, as those two areas have demonstrated the most growth within the last five years in terms of current research.




Transplantation Surgery


Book Description

It is like a fairy story! Or at least a beautiful epic, a truly significant page in the history of medicine, a staggering scene in which several actors come into play, both fundamentalists and clinical practitioners, eager to place all these new developments at the disposal of those suffering from ill health. Everyone is passionate about their work, be it providing new knowledge or perfecting new therapeutic methods. Man has always been fascinated by the possibility of replacing a damaged organ with a healthy one. Several attempts have been made over the centuries, and some miracles have been reported, such as those of Saint Damien and Saint Come as illustrated by Fra Angelico. The modern saga, however, started more modestly on the mouse. It is on the mouse that the first tissue group was discovered; yet the study of human tissue groups could only be carried out on a human. One human must be subjected to the thousands of tests that have enabled us to unravel the extraordinary complexity of the HLA system.




Composite Tissue Allograft


Book Description

This text provides an excellent overview on composite tissue allograft and allograft transplantation. A clear description of the current status of the transplant of every compsite tissue allograft already performed and others which are still at the basic expierimental level.




Introduction to Organ Transplantation


Book Description

This second edition of the introduction to the field of organ transplantation provides an excellent overview of the tremendous progress made in recent decades, and gives a clear description of the current status of transplant surgery for students and trainees with an interest in this field. It opens with introductory chapters on the history of transplantation and the basic science of immunobiology, and then examines through an organ-based structure the practice of transplantation in each major system, from skin to intestine. There is a 13-year gap between the first and second edition, and this is highlighted in the new collection of chapters of this updated version. This is a timely publication produced in line with the rapidly advancing field of transplantation. The editor, Nadey S Hakim, is a consultant transplant and general surgeon at Imperial College Healthcare NHS Trust, London, England, and has put together this second volume that will serve as an invaluable guide for transplant surgeons as well as trainees.




Transplantation at a Glance


Book Description

The first basic overview of all aspects of transplantation with a clarity not to be found in more inaccessible textbooks. This brand new title provides a succinct overview of both the scientific and clinical principles of organ transplantation and the types of organ transplant, featuring highly-illustrated information covering core topics in transplantation including: Organ donors Organ preservation Assessment of transplant recipients Indications for transplantation Immunology of transplantation Immunosuppression and its complications Overviews of thoracic and abdominal organ transplantation, including the kidneys, liver, heart and lungs Transplantation at a Glance is the ideal introduction for medical students, junior doctors, surgical trainees, immunology students, pharmacists, and nurses on transplant wards.




Facial Trauma Surgery E-Book


Book Description

Offering authoritative guidance and a multitude of high-quality images, Facial Trauma Surgery: From Primary Repair to Reconstruction is the first comprehensive textbook of its kind on treating primary facial trauma and delayed reconstruction of both the soft tissues and craniofacial bony skeleton. This unique volume is a practical, complete reference for clinical presentation, fracture pattern, classification, and management of patients with traumatic facial injury, helping you provide the best possible outcomes for patients' successful reintegration into work and society. - Explains the basic principles and concepts of primary traumatic facial injury repair and secondary facial reconstruction. - Offers expert, up-to-date guidance from global leaders in plastic and reconstructive surgery, otolaryngology and facial plastic surgery, oral maxillofacial surgery, neurosurgery, and oculoplastic surgery. - Covers innovative topics such as virtual surgical planning, 3D printing, intraoperative surgical navigation, post-traumatic injury, treatment of facial pain, and the roles of microsurgery and facial transplantation in the treatment facial traumatic injuries. - Includes an end commentary in every chapter provided by Dr. Paul Manson, former Chief of Plastic Surgery at Johns Hopkins Hospital and a pioneer in the field of acute treatment of traumatic facial injuries. - Offers videos that clarify surgical technique, including intraoperative guidance and imaging; transconjunctival approach to the orbit and reconstruction of a zygomaticomaxillary complex fracture; calvarial bone autograft splitting; dental splinting; a systematic method for reading a craniofacial CT scan; and more. - Features superb photographs and illustrations throughout, as well as evidence-based summaries in current areas of controversy. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.




Orthopedic Surgical Oncology For Bone Tumors


Book Description

This atlas presents a collection of richly illustrated teaching cases. It covers the fundamentals of orthopedic oncology complemented with relevant aspects that are demonstrated using individual cases. In a specialty that deals with a relatively smaller number of cases compared to tumors of other systems, this atlas prepares readers for clinical practice by combining a problem-based learning (PBL) approach, which lies on the continuum between structured and guided learning, with theory and practical insights. The book is divided into sections, arranged according to anatomical regions and the reconstruction type. Each section focuses on a specific anatomical region, and each case presentation includes the basic clinical history, basic principles, preoperative, perioperative and radiographic images, a pitfall list, treatment strategy, technical pearls, outcomes and complications. For each region the authors discuss both the biological and non-biological reconstruction techniques. The book is designed to actively involve the reader, making it an invaluable tool for all orthopedic surgeons confronted with oncologic surgery. The book is intended for trainees in orthopedics, orthopedic oncology fellows as well as practicing consultants.




Emerging Transplant Infections


Book Description

The field of transplant medicine has evolved significantly since the first kidney transplant was performed in 1954. Innovations in transplant immunosuppression have lowered the risk of organ rejection so that infectious complications are now the leading cause of hospitalization and mortality after solid organ transplant. Infection is also cited as the leading cause of non-relapse mortality after stem cell transplantation. As transplant centers have recognized the importance of transplant specific expertise in patient outcomes, the field of transplant infectious diseases has expanded into a recognized and highly valued subspecialty. International growth in solid organ and stem cell transplantation has outpaced access to such expertise, with some centers employing microbiology laboratory directors and transplant nephrologists as their lead infectious diseases consultants. This has been a particular challenge as the use of novel immunosuppressive regimens in new geographic and immigrant populations have fueled the emergence of new infection syndromes, with the initial presentation sometimes occurring in this most vulnerable patient population. This digital-first book is designed to meet the needs of practitioners engaged in transplant infectious disease practice who need more depth than they are able to find in UpToDate. It provides an overview of emerging infectious disease challenges with clinically relevant information regarding the epidemiology, diagnosis, management, and prevention of infections in solid organ and stem cell transplant recipients. Each chapter focuses on a clinical syndrome or pathogen with new or emerging implications for transplant patients. Given the rapidly evolving nature of emerging infections and topics in transplant infections, no resource has been published on these increasingly notorious issues; this this text is written by top, global experts who regularly update the material to ensure that readers will always have access to the most cutting edge material available. The editorial team consists of three experienced leaders in the field, all of whom have a strong record of scholarship and publication, as well as an international reputation. All three have focused their academic careers on emerging infectious diseases in transplantation, including a current and a past president of various infectious diseases and transplantation societies. The editors are also experienced reviewers and authors who have collaborated on multiple previous projects. All are committed to this project as a unique opportunity to make an important contribution to their field.




Nasal Reconstruction


Book Description

A nasal reconstruction authority shows you how to obtain the best outcomes and repair unsatisfactory results from former surgeries. In addition to presenting the latest principles and techniques, this new resource also examines evolving concepts and methods, keeping you at the forefront of today's practice. The book emphasizes the restoration of nasal defects-from simple to complex-and achieving normal appearance and function. Comprehensive coverage of all nasal injuries and available surgical methods-both cutting edge as well as older, established approaches-help you choose the best approach for each patient and situation. Full-color clinical photos offer real-life clinical views of conditions and step-by-step surgical results, and a bonus DVD-featuring operative clips-shows techniques in action as well as providing hints and tips for obtaining optimal surgical outcomes. Offers detailed coverage of the principles of nasal reconstruction and application of the aesthetic principles as they apply to the whole face. Discusses design, planning, technique, and pitfalls to avoid for the full range of nasal reconstruction for complete surgical management guidance. Covers the latest topics in reconstruction including three-stage forehead flap . repair of the cocaine nose . advances in the use of free flaps for lining . forehead skin graft . microvascular reconstruction of the nose and face . and revision surgery to equip you to meet a wide range of surgical needs. Features guidance on reconstruction of nasal defects due to cancer, trauma, infection, congential deformity, drug abuse, and collagen vascular disease. Provides expert advice on revision surgery-as well as refinement/touch-up procedures-to effectively handle a previously repaired nose. Includes a DVD with 90 minutes of surgical footage-including cases with a complete 2 stage and a 3 stage folded forehead flap-as well as hints and tips for obtaining optimal surgical outcomes.