Comprehensive B12


Book Description




Could It Be B12?


Book Description

Presenting a wide scope of problems caused by B12 deficiency, this comprehensive guide provides up-to-date medical information about symptoms, testing, diagnosis, and treatment. Written for both the patient and the interested layperson, this detailed book outlines how physicians frequently misdiagnose B12 deficiency as Alzheimer's disease, multiple sclerosis, heart disease, mental retardation, Parkinson's disease, depression, or other mental illnesses. Now in the second edition, this resource has been thoroughly updated with the latest research, diagnostic tests, treatment options, case studies, and testimonials.




Industrial Biotechnology of Vitamins, Biopigments, and Antioxidants


Book Description

Vitamins are a group of physiologically very important, chemically quite complex organic compounds, that are essential for humans and animals. Some vitamins and other growth factors behave as antioxidants, while some can be considered as biopigments. As their chemical synthesis is laborious, their biotechnology-based synthesis and production via microbial fermentation has gained substantial interest within the last decades. Recent progress in microbial genetics and in metabolic engineering and implementation of innovative bioprocess technology has led to a biotechnology-based industrial production of many vitamins and related compounds. Divided into three sections, this volume covers: 1. water-soluble vitamins 2. fat-soluble vitamin compounds and 3. other growth factors, biopigments, and antioxidants. They are all reviewed systematically: from natural occurrence and assays, via biosynthesis, strain development, to industrially-employed biotechnological syntheses and applications.




Laboratory Assessment of Vitamin Status


Book Description

Laboratory Assessment of Vitamin Status provides a comprehensive understanding of the limitations of commonly used approaches used for the evaluation of vitamin status, reducing harm in the general health setting. It outlines the application of 'Best Practice' approaches to the evaluation of vitamin status, giving physicians and other healthcare professionals the opportunity to make evidence-based interventions. Nearly every metabolic and developmental pathway in the human body has a dependency on at least one micronutrient. Currently, the clinical utility of approaches taken by laboratories for the assessment of vitamin status is generally poorly understood, missing the opportunity to diagnosis vitamin deficiencies. This essential reference gives clinical and biomedical scientists an understanding of the limitations of commonly used approaches to the evaluation of vitamin status in the general health setting through change in practice. Nutritionists and dietitians gain an understanding of more sophisticated markers of vitamin status. - Describes specialist assays in sufficient detail to enable laboratories to replicate what is being performed by expert groups - Provides detailed information that supports laboratories in the setting up of methods for the evaluation of vitamin status - Informs laboratories looking for third party providers of specialist investigations - Provides an essential overview of reference ranges for each vitamin




Pernicious Anaemia


Book Description

This book could save you years of ill health! Vitamin B12 definicency, often caused by pernicious anaemia, can be a devastating condition if left untreated, leaing to irreversible nerve damage and disability after years of exhaustion and mental 'fog'. Its symptoms creep up on sufferers and are under-recognised by doctors; tests to confirm it and underlying pernicious anaemia, are problematic. Martyn Hooper, the founder of the Pernicious Anaemia Society, now brings together vital information about the condition and real-life stories - including his own and those of many members of the society - that will help sufferers and their friends and fmailies recognise the condition and understand how best to tackle it. In particular, the book draws on the findings of a survey of society members that give new clarity to the complex issues involved.




Chemistry and Biochemistry of B12


Book Description

A Definitive New Reference for the Latest Advances in B_12 Chemistry and Biochemistry Over the past decade, the field of B_12 research has been revolutionized by such major breakthroughs as the unraveling of the entire biosynthetic pathway for this important vitamin. This comprehensive compendium surveys the wealth of information that has accumulated, covering in one volume virtually all aspects of the field-from physical and inorganic chemistry to enzymology, microbiology, medicine, and diagnostic and therapeutic applications. Edited by Dr. Ruma Banerjee, a highly respected and active member of the B_12 community, this work provides B_12 researchers with a dependable and up-to-date reference on the subject. Leading authorities from five continents explore such new areas as the structural biology of B_12-dependent enzymes, free-radical-mediated reaction mechanisms, biosynthesis, and much more. The role of B_12 in nutrition and disease, and B_12 transport, are also thoroughly examined. Complete with color illustrations and extensive references, Chemistry and Biochemistry of B_12 is a one-of-a-kind resource for biochemists, biophysicists, spectroscopists, microbiologists, molecular biologists, and anyone with an interest in "nature's most beautiful cofactor."




Epidemiology of Communicable and Non-Communicable Diseases


Book Description

Human sufferings, including deaths, can be reduced or avoided by applying routine principles of hygiene in individuals' lives. Some hygiene routines are purely simple remedies, which are inexpensive, affordable, acceptable and easily accessible. It is evident that change is first enacted from within the mindset of an individual, then transmitted to families, groups and communities, and eventually the mindset of a nation can change creating an environment which is better for everybody to live in. This book contains chapters discussing conditions or diseases that may not be common in the readers' area. Caution as such may never be underestimated considering the fact that we are living in a global village where one can never say 'this does not occur in my area' but rather question, does this occur in my community, why does it occur, who is affected, where and when does it occur and what can be done about it? These questions constitute what epidemiology is all about, and their precise and comprehensive answers can transform lives and help us have the right perceptions for the health challenges we face and accept the possibility of dealing with them directly.




Nutrition A Comprehensive Treatise: Vitamins, Nutrient, Requirements, and Food Selection


Book Description

Nutrition, Volume II: Vitamins, Nutrient Requirements, and Food Selection focuses on the requirement, metabolism, and manifestations of deficiency of the individual nutrients. This book discusses the philosophy of dietary standards and compares the dietary standards from several countries. Organized into nine chapters, this volume starts with an overview of the concept of nutritional adaptation and its significance in human nutrition. This text then explains the absorption, transport, and deposition of vitamin A. Other chapters explore the structures, properties, functions, excretions, and toxicities of B vitamins, which include niacin, thiamine, and riboflavin. This book discusses as well the chemistry, absorption, and metabolic functions of pyridoxal phosphate and cobalamin. The final chapter explains the factors affecting food choice in humans and discusses as well the patterns of food use in many areas of the world. This book is a valuable resource for nutritional biochemists, nutritionists, teachers, graduate students, and research workers.




The Comprehensive Physicians' Guide to the Management of PANS and PANDAS


Book Description

An evidence-based guide for doctors diagnosing, testing, and treating children with PANDAS (Pediatric Autoimmune Neuropsychiatric Disorder Associated with Strep infections). In the early 1990s, a group of researchers at the National Institute of Mental Health began collecting data on children who had developed neuropsychiatric disorders (OCD and tics) following infections. They found evidence that antineuronal antibodies had developed in some of these children which attacked the basal ganglia region of the brain. MRI and PET scans in these children demonstrated inflammatory changes in the basal ganglia as well. In 1997, the researchers published the first article to describe this syndrome that they named PANDAS (Pediatric Autoimmune Neuropsychiatric Disorder Associated with Strep infections). In PANDAS, an autoimmune attack on the brain occurs following a Strep infection. PANS (Pediatric Acute-onset Neuropsychiatric Syndrome) is a broader term that also includes cases following exposure to other infections, toxins, and even stress. Clinicians treating children with PANS and PANDAS have found that antibiotics targeted at the offending organisms, steroids, and IVIG results in marked improvement and occasionally complete remission of the neuropsychiatric symptoms. Disturbing symptoms consistent with many DSM-5 psychiatric disorders manifest in patients with PANS and PANDAS—yet we know that there is a biologic basis for the changes in these children. As a result, these disorders require us, as physicians, to view mental illness in an entirely new way. Resistance to this change in paradigm has made PANS and PANDAS difficult for clinicians to diagnose, unbearable for parents to endure, and controversial for scholars to accept. As such, there is no recognized standard of care. We have written this work in an effort to change that. This is a textbook by physicians for physicians. It was written to bring back some of the art of medicine to physicians caring for a group of children and families who really need it. PANS and PANDAS are complex disorders that demand a rich, multifaceted response with novel treatment approaches. The material in this book is assembled from the peer-reviewed medical literature, in combination with over thirty years of clinical experience caring for the sickest patients, both in and out of the hospital. Here you will find conclusive evidence for the existence and pathophysiology of PANS and PANDAS, alongside testing and treatment interventions the author has successfully used in his own practice with hundreds of children. The book concludes with rich appendices including commonly used labs, doses of medications and supplements, a sample flare protocol, extensive support for parents, sample IVIG orders, and much more. We hope this resource allows you, the physician, to help these suffering families heal.




The B12 Deficiency Survival Handbook


Book Description

“If vitamin B12 deficiency is a concern, or you simply want to have a real understanding of this all too common issue, then there is only one book that you should buy. The Vitamin B12 Deficiency Survival Handbook is the authority on all such matters. It is written in a way that allows the layman to understand the issue, and provides the most comprehensive coverage of the topic available as far as I can tell. A must for anyone interested in this issue.” - David Turner, LeanApe.com. Could a lack of vitamin B12 be the reason you're so tired or stressed? What if you were told that something found in your diet could prevent memory loss, Alzheimer and heart disease? What if complex neurological problems, developmental delay in children and infertility in you or a loved one were due to the deficiency of an easily available nutrient? Those associations (and many more) aren't just speculations or proposed theories – these theories have all risen up due to observations made by numerous people and have been proven by the help of research. That means they're not just theories - they're proven facts. This is what our new book is about – B12. Time to de-construct the mystery behind this vitamin to small, manageable, easy-to-understand pieces. “Vitamin B12 is the only nutrient not supplied by a vegan diet. Therefore when I saw Aqsa and Regev's book, I knew I had to read it. It's a great read full of bonafide references. I'm sure I could have found the majority of the information on the topic doing my own research online, but the time investment required would have been huge. Getting the book at a discounted rate just made it even better value.” - Andy Cowan, JuiceFiend.co.uk. “The B12 Deficiency Survival Handbook” is the direct result of hours and hours and hours of data-crunching, research papers and case studies, separating the junk from the real legit science. With plenty of specialist help and on the shoulders of giant scientists, we managed to create this resource and we're very confident it's going to solve all your B12 issues. Avoid Serious and Often Irreversible Damage B12 deficiency is not a joke, it can wreck havoc on your health. It's one of the most underrated yet destructive conditions relevant in the western society today, and early treatment can literally save your life. * Avoid or Treat Your Anemia * Avoid Irreversible Nervous and Brain Damage * Depressed? Get Your Happiness Back! * Have a LOT More Energy * Don't Lose Your Eyesight * Keep Your Hormones In Good Shape and Feel Like Wolverine * Avoid Ageing and Alzheimer * Have a Better Concentration and Memory * Protect Your Child From Autism and Developmental Abnormalities “The B12 Deficiency Survival Handbook” Got You Covered. You'll Discover The Best Possible Solutions For Your Specific Deficiency. Guaranteed. Save a Huge Amount of Time and Money You would otherwise spend on future medical procedures, supplements or other unnecessary fluff. That's right, not buying this book will actually cost you MORE money. Can you afford that? You will also save a lot of time by learning how to avoid or treat this condition early on. Believe me, you don't want to find yourself spending weeks or months in a hospital. The earlier you treat it – the less complicated it becomes. Anything Else? Definitely. Through the book you'll learn to understand: All Functions and Aspects of Vitamin B12 Where B12 Comes From The Best Natural Sources and Foods The Absorption Process of B12 How B12 Deficiency Is Treated How to Choose The Best Supplement for YOU Why People Become Deficient In B12 Very Similar Conditions That Are Easily Mistakable The Signs and Symptoms of a B12 Deficiency The Different Stages of B12 deficiency Get your hands on your book before it gets too late and you suffer irreversible nervous damage!