Comprehensive Insights into Ampullary Cancer: From Pathogenesis to Patient-Centered Care


Book Description

Delve into the intricate world of ampullary cancer with our comprehensive treatise, 'Comprehensive Insights into Ampullary Cancer: From Pathogenesis to Patient-Centered Care.' This meticulously crafted exploration offers a deep and holistic understanding of ampullary cancer, a complex malignancy originating at the junction of the common bile duct and the pancreatic duct. The treatise begins by defining and classifying ampullary cancer, providing a solid foundation for readers. Epidemiology and incidence are thoroughly examined, shedding light on the prevalence and distribution of this rare but clinically significant disease. As we navigate through the chapters, attention is devoted to unraveling the intricate web of risk factors, genetic predispositions, and the clinical presentation of ampullary cancer. Embarking on a journey into the anatomy and biochemistry of ampullary cancer, readers gain insights into morphological structures, functional significance, blood supply, lymphatic drainage, neural innervation, and the role of the ampulla in digestive processes. The treatise then delves into the cellular pathways, genetic mutations, tumor microenvironment, immune system interactions, and the role of inflammation in ampullary cancer progression.




Genetics of Colorectal Cancer


Book Description

Genetic susceptibility refers to how variations in a person’s genes increase or decrease his or her susceptibility to environmental factors, such as chemicals, radiation and lifestyle (diet and smoking). This volume will explore the latest findings in the area of genetic susceptibility to gastrointestinal cancers, focusing on molecular epidemiology, DNA repair, and gene-environment interactions to identify factors that affect the incidence of GI cancers. Topics will include germline susceptibility, including Mendelian patterns of inheritance and gene-environment interactions that lead to cancer etiology.




Textbook of General Surgical Oncology


Book Description

A resource that combines oncologic principles with treatment plans for the surgical management of neoplasms Textbook of General Surgical Oncology is a practical and comprehensive reference that offers authoritative coverage of a wide variety of oncologic concepts and disorders. The book opens with detailed discussion of the general principles of molecular biology, cancer epidemiology, surgical oncology, radiation oncology, medical oncology, immunotherapy, nuclear imaging, and molecular diagnostics. The text then focuses on site-specific neoplasms, such as those of the skin, soft tissue, bone, head/neck, brain, lung, mediastinum, breast, pleura, peritoneum, as well as tumors that affect various systems, including the endocrine, gastrointestinal, hepatobiliary, genitourinary, gynecologic, and hematopoietic. · Each chapters is written by an internationally recognized expert on the topic · Learning aids include chapter-ending Q&A and Practical Pearls · Outstanding review for the new General Surgical Oncology certification examination







Diagnosis and Management of Cholangiocarcinoma


Book Description

This book provides a comprehensive, state-of-the-art overview of cholangiocarcinoma (CCA). The text is structured to effectively present a broad yet concise overview of bile duct cancer, its relevant definitions, classification schemata, clinical management tenets, translational (including molecular and cellular) facets, and future directions. The book features numerous high-yield illustrations and is authored by an eclectic range of renowned experts in various areas of CCA, reflecting the multidisciplinary nature of the field. Filling a critical gap in the field, Diagnosis and Management of Cholangiocarcinoma: A Multidisciplinary Approach is a valuable resource for clinicians and practitioners who treat patients with bile duct cancer.




IgG4-Related Sclerosing Cholangitis


Book Description

This book aims to raise awareness of IgG4-related sclerosing cholangitis among practicing physicians and to equip readers with a sound understanding of the principles of diagnosis and treatment. Clinical, serological, and histopathological features are clearly described and imaging appearances on all relevant modalities are illustrated, covering the bile duct and other involved organs. Differential diagnosis from other diseases, including primary sclerosing cholangitis and cholangiocarcinoma, is precisely explained. Information is then presented on all significant current and emerging therapeutic strategies, including steroids, immunosuppressive drugs, and rituximab. Finally, attention is drawn to significant prognostic features. While IgG4-related sclerosing cholangitis is now a widely acknowledged condition, most practitioners are still liable to misdiagnose it owing to a lack of familiarity with its presenting features. This book should help to rectify the situation and will be an asset for all who may encounter the disease in clinical practice.




WHO Classification of Tumours of the Digestive System


Book Description

"The WHO Classification of Tumours of the Digestive System presented in this book reflects the views of a Working Group that convened for an Editorial and Consensus Conference at the International Agency for Research on Cancer (IARC), Lyon, December 10-12, 2009"--P. [5].




Autoimmune Liver Diseases


Book Description

The second edition, which appears seven years after the first, is a more comprehensive text and addresses the many recent advances in basic and clinical science applicable to autoimmune hepatitis, primary biliary cirrhosis, primary sclerosing cholangitis, and autoimmune aspects of viral-, drug- and alcohol-induced liver disease and hepatocellular cancer. Pathogenesis, diagnosis and treatment are discussed in depth in light of current understanding of the molecular mechanisms of autoimmunity as it applies to liver disease.




Colorectal Cancer Screening


Book Description

Colorectal Cancer Screening provides a complete overview of colorectal cancer screening, from epidemiology and molecular abnormalities, to the latest screening techniques such as stool DNA and FIT, Computerized Tomography (CT) Colonography, High Definition Colonoscopes and Narrow Band Imaging. As the text is devoted entirely to CRC screening, it features many facts, principles, guidelines and figures related to screening in an easy access format. This volume provides a complete guide to colorectal cancer screening which will be informative to the subspecialist as well as the primary care practitioner. It represents the only text that provides this up to date information about a subject that is continually changing. For the primary practitioner, information on the guidelines for screening as well as increasing patient participation is presentedd. For the subspecialist, information regarding the latest imaging techniques as well as flat adenomas and chromoendoscopy are covered. The section on the molecular changes in CRC will appeal to both groups. The text includes up to date information about colorectal screening that encompasses the entire spectrum of the topic and features photographs of polyps as well as diagrams of the morphology of polyps as well as photographs of CT colonography images. Algorithms are presented for all the suggested guidelines. Chapters are devoted to patient participation in screening and risk factors as well as new imaging technology. This useful volume explains the rationale behind screening for CRC. In addition, it covers the different screening options as well as the performance characteristics, when available in the literature, for each test. This volume will be used by the sub specialists who perform screening tests as well as primary care practitioners who refer patients to be screened for colorectal cancer.




Cancer Medicine


Book Description