Computation and Neural Systems


Book Description

Computational neuroscience is best defined by its focus on understanding the nervous systems as a computational device rather than by a particular experimental technique. Accordinlgy, while the majority of the papers in this book describe analysis and modeling efforts, other papers describe the results of new biological experiments explicitly placed in the context of computational issues. The distribution of subjects in Computation and Neural Systems reflects the current state of the field. In addition to the scientific results presented here, numerous papers also describe the ongoing technical developments that are critical for the continued growth of computational neuroscience. Computation and Neural Systems includes papers presented at the First Annual Computation and Neural Systems meeting held in San Francisco, CA, July 26--29, 1992.




Computation in Neurons and Neural Systems


Book Description

Computation in Neurons and Neural Systems contains the collected papers of the 1993 Conference on Computation and Neural Systems which was held between July 31--August 7, in Washington, DC. These papers represent a cross-section of the state-of-the-art research work in the field of computational neuroscience, and includes coverage of analysis and modeling work as well as results of new biological experimentation.




Single Neuron Computation


Book Description

This book contains twenty-two original contributions that provide a comprehensive overview of computational approaches to understanding a single neuron structure. The focus on cellular-level processes is twofold. From a computational neuroscience perspective, a thorough understanding of the information processing performed by single neurons leads to an understanding of circuit- and systems-level activity. From the standpoint of artificial neural networks (ANNs), a single real neuron is as complex an operational unit as an entire ANN, and formalizing the complex computations performed by real neurons is essential to the design of enhanced processor elements for use in the next generation of ANNs.The book covers computation in dendrites and spines, computational aspects of ion channels, synapses, patterned discharge and multistate neurons, and stochastic models of neuron dynamics. It is the most up-to-date presentation of biophysical and computational methods.




Biophysics of Computation


Book Description

Neural network research often builds on the fiction that neurons are simple linear threshold units, completely neglecting the highly dynamic and complex nature of synapses, dendrites, and voltage-dependent ionic currents. Biophysics of Computation: Information Processing in Single Neurons challenges this notion, using richly detailed experimental and theoretical findings from cellular biophysics to explain the repertoire of computational functions available to single neurons. The author shows how individual nerve cells can multiply, integrate, or delay synaptic inputs and how information can be encoded in the voltage across the membrane, in the intracellular calcium concentration, or in the timing of individual spikes.Key topics covered include the linear cable equation; cable theory as applied to passive dendritic trees and dendritic spines; chemical and electrical synapses and how to treat them from a computational point of view; nonlinear interactions of synaptic input in passive and active dendritic trees; the Hodgkin-Huxley model of action potential generation and propagation; phase space analysis; linking stochastic ionic channels to membrane-dependent currents; calcium and potassium currents and their role in information processing; the role of diffusion, buffering and binding of calcium, and other messenger systems in information processing and storage; short- and long-term models of synaptic plasticity; simplified models of single cells; stochastic aspects of neuronal firing; the nature of the neuronal code; and unconventional models of sub-cellular computation.Biophysics of Computation: Information Processing in Single Neurons serves as an ideal text for advanced undergraduate and graduate courses in cellular biophysics, computational neuroscience, and neural networks, and will appeal to students and professionals in neuroscience, electrical and computer engineering, and physics.




Computation and Neural Systems


Book Description

Computational neuroscience is best defined by its focus on understanding the nervous systems as a computational device rather than by a particular experimental technique. Accordinlgy, while the majority of the papers in this book describe analysis and modeling efforts, other papers describe the results of new biological experiments explicitly placed in the context of computational issues. The distribution of subjects in Computation and Neural Systems reflects the current state of the field. In addition to the scientific results presented here, numerous papers also describe the ongoing technical developments that are critical for the continued growth of computational neuroscience. Computation and Neural Systems includes papers presented at the First Annual Computation and Neural Systems meeting held in San Francisco, CA, July 26--29, 1992.




From Neuron to Cognition via Computational Neuroscience


Book Description

A comprehensive, integrated, and accessible textbook presenting core neuroscientific topics from a computational perspective, tracing a path from cells and circuits to behavior and cognition. This textbook presents a wide range of subjects in neuroscience from a computational perspective. It offers a comprehensive, integrated introduction to core topics, using computational tools to trace a path from neurons and circuits to behavior and cognition. Moreover, the chapters show how computational neuroscience—methods for modeling the causal interactions underlying neural systems—complements empirical research in advancing the understanding of brain and behavior. The chapters—all by leaders in the field, and carefully integrated by the editors—cover such subjects as action and motor control; neuroplasticity, neuromodulation, and reinforcement learning; vision; and language—the core of human cognition. The book can be used for advanced undergraduate or graduate level courses. It presents all necessary background in neuroscience beyond basic facts about neurons and synapses and general ideas about the structure and function of the human brain. Students should be familiar with differential equations and probability theory, and be able to pick up the basics of programming in MATLAB and/or Python. Slides, exercises, and other ancillary materials are freely available online, and many of the models described in the chapters are documented in the brain operation database, BODB (which is also described in a book chapter). Contributors Michael A. Arbib, Joseph Ayers, James Bednar, Andrej Bicanski, James J. Bonaiuto, Nicolas Brunel, Jean-Marie Cabelguen, Carmen Canavier, Angelo Cangelosi, Richard P. Cooper, Carlos R. Cortes, Nathaniel Daw, Paul Dean, Peter Ford Dominey, Pierre Enel, Jean-Marc Fellous, Stefano Fusi, Wulfram Gerstner, Frank Grasso, Jacqueline A. Griego, Ziad M. Hafed, Michael E. Hasselmo, Auke Ijspeert, Stephanie Jones, Daniel Kersten, Jeremie Knuesel, Owen Lewis, William W. Lytton, Tomaso Poggio, John Porrill, Tony J. Prescott, John Rinzel, Edmund Rolls, Jonathan Rubin, Nicolas Schweighofer, Mohamed A. Sherif, Malle A. Tagamets, Paul F. M. J. Verschure, Nathan Vierling-Claasen, Xiao-Jing Wang, Christopher Williams, Ransom Winder, Alan L. Yuille




Principles of Computational Modelling in Neuroscience


Book Description

Learn to use computational modelling techniques to understand the nervous system at all levels, from ion channels to networks.




Theoretical Neuroscience


Book Description

Theoretical neuroscience provides a quantitative basis for describing what nervous systems do, determining how they function, and uncovering the general principles by which they operate. This text introduces the basic mathematical and computational methods of theoretical neuroscience and presents applications in a variety of areas including vision, sensory-motor integration, development, learning, and memory. The book is divided into three parts. Part I discusses the relationship between sensory stimuli and neural responses, focusing on the representation of information by the spiking activity of neurons. Part II discusses the modeling of neurons and neural circuits on the basis of cellular and synaptic biophysics. Part III analyzes the role of plasticity in development and learning. An appendix covers the mathematical methods used, and exercises are available on the book's Web site.




Neural Networks and Analog Computation


Book Description

The theoretical foundations of Neural Networks and Analog Computation conceptualize neural networks as a particular type of computer consisting of multiple assemblies of basic processors interconnected in an intricate structure. Examining these networks under various resource constraints reveals a continuum of computational devices, several of which coincide with well-known classical models. On a mathematical level, the treatment of neural computations enriches the theory of computation but also explicated the computational complexity associated with biological networks, adaptive engineering tools, and related models from the fields of control theory and nonlinear dynamics. The material in this book will be of interest to researchers in a variety of engineering and applied sciences disciplines. In addition, the work may provide the base of a graduate-level seminar in neural networks for computer science students.




Neuronal Dynamics


Book Description

This solid introduction uses the principles of physics and the tools of mathematics to approach fundamental questions of neuroscience.