Computer Simulation of X-Ray Capillary Optics for Digital Mammography


Book Description

Polycapillary x-ray optics, arrays of hollow capillary tubes used to guide x-rays by total reflectance, are now being used in increasing numbers of applications, such as materials analysis, microelectronics manufacturing, x-ray astronomy and medical imaging. Because each optic contains hundreds of thousands of precisely shaped and located hollow channels, it is desirable to assess the feasibility of a variety of capillary geometries for a new application without physically constructing the optic. This assessment requires increasingly sophisticated modeling capability as new applications with more stringent requirements are developed. Previous analysis has shown that high-energy applications such as hard x-ray astronomy and medical imaging are particularly sensitive to optic profile errors such as channel waviness. A more physical model for surface waviness has been developed and included in optics simulations. The results are compared to measured data and to the results of other numerical simulation programs. Directed digital mammography can avail itself the advantages of digital processing, including tolerance to under- and over-exposure and image enhancement. In addition, a new technology, polycapillary optics, has been shown to produce clearer image by increasing contrast and resolution. Capillary optics, consisting a array of hollow glass tubes, is a relatively new technology for controlling x-ray beams. Thousands of individual capillary fiber can be strung together to form a multifiber optic. These arrays of curve polycapillary fiber can be used to focus, collimate, and filter x-ray radiation. A number of borrosilicate glass capillary fibers have been measured and simulated in the energy range 10-80 keV. The result shown potential for mammography applications, with transmission of 70% at 20 keV.




Simulation, Measurements and Image Processing for Capillary Optical Digital Mammography


Book Description

An extensive computer modeling for polycapillary optics that includes realistic models for the effects of profile defects shows good agreement with measured data. Measured polycapillary fiber transmission is in excess of 65% at 20 keV for borosilicate glass optics, and is in excess of 42% for short leaded glass optics. Measured high angle transmission which corresponds to scatter transmission is lower than 1% for 12 cm long borosilicate optics at 20 kev and less than 4% for 3 cm long leaded glass optics at 80 keV. A long prototype borosilicate magnifying tapered monolithic optic has demonstrated contrast enhancement due to removal of scatter transmission, while at the same time increasing the system MTF performance at all spatial frequencies. Computer modeling, measurement and defect studies have led to better manufacturing capabilities for monolithic optics. The newly magnifying monolithic optics have a high transmission efficiency. Multitaper optics have been produced and tested. Image analysis have provided the means for the image artifact analysis and reduction.




Direct Digital Mammography Using Capillary Optics


Book Description

The overall objective of this proposal is to develop a mammographic system with extremely high scatter rejection and dynamic range, good resolution and low patient dose. This will be accomplished by developing a direct x-ray detector interfaced with a capillary x-ray optic in an appropriately designed mammographic system. Measurements have been performed of transmission and absorbence of single capillaries. Preliminary measurements have been performed of pre-prototype optics. These measurements indicate that capillary x-ray optics should be suitable for enhancing contrast and performing beam shaping for matching with digital detectors. Simulation work on a collimating optic has shown good agreement with data and is progressing, which has allowed some design decisions for a suitable optic to be made. A prototype linear detector array has been constructed, along with readout electronics. A single pixel detector has been characterized.




Simulation, Measurements and Image Processing for Capillary Optical Digital Mammorgraphy (96 Breast)


Book Description

Capillary optics, which use total external reflection to transmit x rays, have been proved to have great advantages in scatter reduction and resolution improvement in mammography application. The purpose of the proposed work is to perform lens simulation and image artifact elimination as part of the work of capillary optical mammography research. A lens simulation extended from the-previous single fiber simulation has been implemented, a lens for the protocol mammography system has been re-measured in an extended energy range and analyzed with the program. The simulation has been proved to be helpful in understanding the lens performance. Modulation Transfer Function (MTF) is the most fundamental measurement of spatial resolution used in radiology. Non-uniform transmission introduces difficulties in MTF measurement. A method to measure MTF by taking an edge image and processed with background reduction technique has been developed. The modeling capability has been extended and has lead to a real development of understanding of the nature of polycapillary defects, which is already leading to improvements in the manufacturing processes. Further, the increased confidence in the modeling allows future lens geometries to be effectively "tested" in simulation so that design parameters can be rapidly optimized.







Measurements of X-Ray Capillary Optics for Digital Mammography


Book Description

Results of extensive mammography screenings have shown the need for detection of breast cancer at earlier and more curable stages to have any significant impact on the mortality rate. While new imaging technologies for breast cancer diagnosis like magnetic resonance imaging, breast ultrasound and breast specific positron emission tomography are being developed, x%ray imaging continues to function as a convenient and economical choice for early detection.







Digital Mammography


Book Description

Digital Radiography has been ? rmly established in diagnostic radiology during the last decade. Because of the special requirements of high contrast and spatial resolution needed for roentgen mammography, it took some more time to develop digital m- mography as a routine radiological tool. Recent technological progress in detector and screen design as well as increased ex- rience with computer applications for image processing have now enabled Digital Mammography to become a mature modality that opens new perspectives for the diag- sis of breast diseases. The editors of this timely new volume Prof. Dr. U. Bick and Dr. F. Diekmann, both well-known international leaders in breast imaging, have for many years been very active in the frontiers of theoretical and translational clinical research, needed to bring digital mammography ? nally into the sphere of daily clinical radiology. I am very much indebted to the editors as well as to the other internationally rec- nized experts in the ? eld for their outstanding state of the art contributions to this v- ume. It is indeed an excellent handbook that covers in depth all aspects of Digital Mammography and thus further enriches our book series Medical Radiology. The highly informative text as well as the numerous well-chosen superb illustrations will enable certi? ed radiologists as well as radiologists in training to deepen their knowledge in modern breast imaging.




Monochromatic Mammographic Imaging Using X-Ray Polycapillary Optics


Book Description

Collimated (parallel) beams can be used to remove scatter and improve resolution. Monochromatic x rays can be used to produce higher contrast images. Polycapillary x-ray optics technology can produce a highly parallel, monochromatic, x-ray beam from a conventional radiographic source. Two prototype collimating optics were characterized. The one with the higher transmission was used for monochromatic imaging. The transmission for prototype II optic with a focal distance of 250 mm was 37 % at 17.5 keV. The optic had good field uniformity and collected efficiently from a source up to 0.7 mm in diameter. The divergence of collimation was only 3.9 + 0.3 mrad. This shows the efficiency with which the beam can be monochromatized. These data were verified with computer simulations of ideal collimating optics. The contrast results agreed with the theoretical calculations at 8 keV. The monochromatic values are on the average 5 times higher than the polychromatic case. At mammographic energies, 20 keV, the expected contrast enhancement is 2.0 for 60 mm thick phantoms in addition to the contrast enhancement achieved from scatter reduction. The high contrast achievable with monochromatic parallel beam imaging has thus been demonstrated with a conventional source.