Cross-Section of a Human Heart


Book Description

"'The first thing I'm going to do with my winnings, ' he said, 'is pay for laser hair removal in your armpits.' He even gestured to my cleanly shaven pits, because if referencing a woman's body hair on a date doesn't awaken her inner vixen, pointing to its location is sure to do the trick."An introverted Midwesterner with big feelings and a shameful people-pleasing streak, Abi Wurdeman hoped her twenties would transform her into one of those fierce, take-charge broads quoted on sassy refrigerator magnets. But somewhere between facing her own demons at a soul-sucking casino job and making the occasional ill-timed confession of love, Abi learned you can't reinvent who you fundamentally are . . . and that the secret to adult tenacity lies not in changing yourself, but in knowing yourself.Ninety percent memoir and ten percent unsolicited advice, Cross-Section of a Human Heart is the story of a floundering journey from mousey young adult to proper grown-ass.




Advanced Drug Delivery


Book Description

Provides both fundamentals and new and emerging applications Advanced Drug Delivery brings readers fully up to date with the state of the science, presenting the basics, formulation strategies, and therapeutic applications of advanced drug delivery. The book demonstrates how core concepts of pharmaceutical sciences, chemistry, and molecular biology can be combined and applied in order to spark novel ideas to design and develop advanced drug delivery systems for the treatment of a broad range of human diseases. Advanced Drug Delivery features contributions from an international team of pharmaceutical scientists. Chapters reflect a thorough review and analysis of the literature as well as the authors' firsthand experience developing drug delivery systems. The book is divided into four parts: Part I, Introduction and Basics of Advanced Drug Delivery, explores physiological barriers, stability, transporters, and biomaterials in drug delivery Part II, Strategies for Advanced Drug Delivery, offers tested and proven strategies for advanced delivery of both small molecules and macromolecules Part III, Translational Research of Advanced Drug Delivery, focuses on regulatory considerations and translational applications of advanced drug delivery systems for the treatment of cardiovascular diseases, cancer, sexually transmitted diseases, ophthalmic diseases, and brain diseases Part IV, Future Applications of Advanced Drug Delivery in Emerging Research Areas, examines stem cell research, cell-based therapeutics, tissue engineering, and molecular imaging Each chapter provides objectives and assessment questions to help readers grasp key concepts and assess their knowledge as they progress through the book. Advanced Drug Delivery is recommended for graduates and upper-level undergraduates in the pharmaceutical sciences who need a solid foundation in the basics. It is also recommended for pharmaceutical professionals who want to take advantage of new and emerging applications in advanced drug delivery systems.




Regulation of Tissue Oxygenation, Second Edition


Book Description

This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.




Anatomy and Physiology


Book Description




Pathology of Heart Disease in the Fetus, Infant and Child


Book Description

Clearly presents the pathology of heart disease from fetus to adolescence, integrating histology and macroscopy with effects of treatment.




Regulation of Coronary Blood Flow


Book Description

Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow.




Stephen Biesty's Incredible Body Cross-Sections


Book Description

A book that actually takes you inside - and around - the human body to see how it works, with the help of some truly unique illustrations and some very small people! Explore your brain, your bones, and everything in between in incredible cross-section drawings of all the body systems. Inside each one are teams of tiny characters busy at work, and explaining what's going on. Every page is packed with jaw-dropping facts. Did you know that the skin is your largest organ - in an adult it's 2 sq m (22 sq ft). Have you ever thought about how heavy the brain is? Well, it's about 1.4 kg (3 lb) and is crammed with 100 billion nerve cells that help you think and move. And by the time you turn 75, your heart will have pumped blood around your body 4,000 million times! With the challenge of finding two tiny explorers making their way through the body, learning about anatomy has never been so much fun!




Text-book of Histology


Book Description




Handbook of Cardiac Anatomy, Physiology, and Devices


Book Description

This book covers the latest information on the anatomic features, underlying physiologic mechanisms, and treatments for diseases of the heart. Key chapters address animal models for cardiac research, cardiac mapping systems, heart-valve disease and genomics-based tools and technology. Once again, a companion of supplementary videos offer unique insights into the working heart that enhance the understanding of key points within the text. Comprehensive and state-of-the art, the Handbook of Cardiac Anatomy, Physiology and Devices, Third Edition provides clinicians and biomedical engineers alike with the authoritative information and background they need to work on and implement tomorrow’s generation of life-saving cardiac devices.