Cyclic Nucleotide Phosphodiesterases in Health and Disease


Book Description

Since the last major compendium dedicated to cyclic nucleotide phosphodiesterases (PDEs) was published over 15 years ago, an enormous amount of progress has occurred in the field. There is great need for a centralized source for key information in this burgeoning and therapeutically important area of medical research. Cyclic Nucleotide Phosph




Cyclic Nucleotide Signaling


Book Description




Current Catalog


Book Description

First multi-year cumulation covers six years: 1965-70.




Ions-Cyclic Nucleotides-Cholinergy


Book Description

Advances in Pharmacology and Therapeutics, Volume 3: Ions – Cyclic Nucleotides – Cholinergy covers the proceedings of the Seventh International Congress of Pharmacology, held in Paris in 1978. This book mainly focuses on studying ions, cyclic nucleotides, and cholinergy. Specifically, this text discusses the pharmacology of calcium homeostasis and presents lectures given in the symposium. The role of cyclic nucleotides in the regulation of muscular tissue functions and the evaluation of cyclic AMP and cyclic GMP are also looked into. This text presents in its latter part papers on chemical structure and cholinergic activity. This volume will be valuable to students and experts in the field of pharmacology, therapeutics, and related fields.




Therapeutic Oligonucleotides


Book Description

This book provides a compelling overall update on current status of RNA interference







Hormones, Metabolism and the Benefits of Exercise


Book Description

The world is faced with an epidemic of metabolic diseases such as obesity and type 2 diabetes. This is due to changes in dietary habits and the decrease in physical activity. Exercise is usually part of the prescription, the first line of defense, to prevent or treat metabolic disorders. However, we are still learning how and why exercise provides metabolic benefits in human health. This open access volume focuses on the cellular and molecular pathways that link exercise, muscle biology, hormones and metabolism. This will include novel “myokines” that might act as new therapeutic agents in the future.




Bioenvironmental Issues Affecting Men's Reproductive and Sexual Health


Book Description

Bioenvironmental Issues Affecting Men's Reproductive and Sexual Health is structured into two parts related to men's reproductive and sexual health with eight sections designed to enable a logical flow of such knowledge. The book is focused on the biology of key organs involved in male reproduction and the environmental influences affecting their functions with particular emphasis on clinical aspects. Individual chapters within the book range from basic to translational aspects, but all hold clinical relevance. This is an essential reference for those working and learning in the field of human reproduction, reproductive toxicology and environmental influences on reproductive and sexual health. - Brings together the leading authorities working in the field of male reproduction and sexual health and how the environment affects these issues - Provides guidelines and reference values of various reproductive hormones, semen parameters, inclusion/exclusion criteria for clinical trials - Discover the most efficient methods by which to design clinical protocols for sperm safety studies and reproductive toxicology trials




Neuropsychopharmacology


Book Description

Advances in Pharmacology and Therapeutics, Volume 5: Neuropsychopharmacology contains the proceedings of the 7th International Congress of Pharmacology held in Paris, France, in 1978. The papers explore advances in the understanding of neuropsychopharmacology and cover topics ranging from anti-schizophrenic drugs to drug pathways in depression treatment. Pharmacological interferences with nonstriatal dopaminergic systems are also discussed. This volume is comprised of 21 chapters and opens by considering the nanomolar affinity of pre- and post-synaptic dopamine receptors for neuroleptics. The next section deals with drug pathways in the treatment of depression, with particular reference to the biochemical mechanisms of depressive states and the therapeutic effects of some antidepressants. The following chapters examine dopamine receptors in the nucleus accumbens; modulation of mesolimbic dopamine mechanisms via serotonin and GABA; how mesocortical dopaminergic neurons react to stress; and the behavioral consequences of the interaction between morphine, substance P, and nonstriatal dopamine neurons. This book will be of interest to practitioners in biosciences, pharmacology, physiology, psychology, neurology, and medicine.