Data Analysis and Applications 1


Book Description

This series of books collects a diverse array of work that provides the reader with theoretical and applied information on data analysis methods, models, and techniques, along with appropriate applications. Volume 1 begins with an introductory chapter by Gilbert Saporta, a leading expert in the field, who summarizes the developments in data analysis over the last 50 years. The book is then divided into three parts: Part 1 presents clustering and regression cases; Part 2 examines grouping and decomposition, GARCH and threshold models, structural equations, and SME modeling; and Part 3 presents symbolic data analysis, time series and multiple choice models, modeling in demography, and data mining.




Data Analysis and Applications 4


Book Description

Data analysis as an area of importance has grown exponentially, especially during the past couple of decades. This can be attributed to a rapidly growing computer industry and the wide applicability of computational techniques, in conjunction with new advances of analytic tools. This being the case, the need for literature that addresses this is self-evident. New publications are appearing, covering the need for information from all fields of science and engineering, thanks to the universal relevance of data analysis and statistics packages. This book is a collective work by a number of leading scientists, analysts, engineers, mathematicians and statisticians who have been working at the forefront of data analysis. The chapters included in this volume represent a cross-section of current concerns and research interests in these scientific areas. The material is divided into three parts: Financial Data Analysis and Methods, Statistics and Stochastic Data Analysis and Methods, and Demographic Methods and Data Analysis- providing the reader with both theoretical and applied information on data analysis methods, models and techniques and appropriate applications.




Pharmacokinetic and Pharmacodynamic Data Analysis: Concepts and Applications, Third Edition


Book Description

This is a revised and very expanded version of the previous second edition of the book. "Pharmacokinetic and Pharmacodynamic Data Analysis" provides an introduction into pharmacokinetic and pharmacodynamic concepts using simple illustrations and reasoning. It describes ways in which pharmacodynamic and pharmacodynamic theory may be used to give insight into modeling questions and how these questions can in turn lead to new knowledge. This book differentiates itself from other texts in this area in that it bridges the gap between relevant theory and the actual application of the theory to real life situations. The book is divided into two parts; the first introduces fundamental principles of PK and PD concepts, and principles of mathematical modeling, while the second provides case studies obtained from drug industry and academia. Topics included in the first part include a discussion of the statistical principles of model fitting, including how to assess the adequacy of the fit of a model, as well as strategies for selection of time points to be included in the design of a study. The first part also introduces basic pharmacokinetic and pharmacodynamic concepts, including an excellent discussion of effect compartment (link) models as well as indirect response models. The second part of the text includes over 70 modeling case studies. These include a discussion of the selection of the model, derivation of initial parameter estimates and interpretation of the corresponding output. Finally, the authors discuss a number of pharmacodynamic modeling situations including receptor binding models, synergy, and tolerance models (feedback and precursor models). This book will be of interest to researchers, to graduate students and advanced undergraduate students in the PK/PD area who wish to learn how to analyze biological data and build models and to become familiar with new areas of application. In addition, the text will be of interest to toxicologists interested in learning about determinants of exposure and performing toxicokinetic modeling. The inclusion of the numerous exercises and models makes it an excellent primary or adjutant text for traditional PK courses taught in pharmacy and medical schools. A diskette is included with the text that includes all of the exercises and solutions using WinNonlin.




Data Analysis and Applications 4


Book Description

Data analysis as an area of importance has grown exponentially, especially during the past couple of decades. This can be attributed to a rapidly growing computer industry and the wide applicability of computational techniques, in conjunction with new advances of analytic tools. This being the case, the need for literature that addresses this is self-evident. New publications are appearing, covering the need for information from all fields of science and engineering, thanks to the universal relevance of data analysis and statistics packages. This book is a collective work by a number of leading scientists, analysts, engineers, mathematicians and statisticians who have been working at the forefront of data analysis. The chapters included in this volume represent a cross-section of current concerns and research interests in these scientific areas. The material is divided into three parts: Financial Data Analysis and Methods, Statistics and Stochastic Data Analysis and Methods, and Demographic Methods and Data Analysis- providing the reader with both theoretical and applied information on data analysis methods, models and techniques and appropriate applications.




Methods and Applications of Longitudinal Data Analysis


Book Description

Methods and Applications of Longitudinal Data Analysis describes methods for the analysis of longitudinal data in the medical, biological and behavioral sciences. It introduces basic concepts and functions including a variety of regression models, and their practical applications across many areas of research. Statistical procedures featured within the text include: descriptive methods for delineating trends over time linear mixed regression models with both fixed and random effects covariance pattern models on correlated errors generalized estimating equations nonlinear regression models for categorical repeated measurements techniques for analyzing longitudinal data with non-ignorable missing observations Emphasis is given to applications of these methods, using substantial empirical illustrations, designed to help users of statistics better analyze and understand longitudinal data. Methods and Applications of Longitudinal Data Analysis equips both graduate students and professionals to confidently apply longitudinal data analysis to their particular discipline. It also provides a valuable reference source for applied statisticians, demographers and other quantitative methodologists. From novice to professional: this book starts with the introduction of basic models and ends with the description of some of the most advanced models in longitudinal data analysis Enables students to select the correct statistical methods to apply to their longitudinal data and avoid the pitfalls associated with incorrect selection Identifies the limitations of classical repeated measures models and describes newly developed techniques, along with real-world examples.




Longitudinal and Panel Data


Book Description

An introduction to foundations and applications for quantitatively oriented graduate social-science students and individual researchers.




Handbook of Statistical Analysis and Data Mining Applications


Book Description

Handbook of Statistical Analysis and Data Mining Applications, Second Edition, is a comprehensive professional reference book that guides business analysts, scientists, engineers and researchers, both academic and industrial, through all stages of data analysis, model building and implementation. The handbook helps users discern technical and business problems, understand the strengths and weaknesses of modern data mining algorithms and employ the right statistical methods for practical application. This book is an ideal reference for users who want to address massive and complex datasets with novel statistical approaches and be able to objectively evaluate analyses and solutions. It has clear, intuitive explanations of the principles and tools for solving problems using modern analytic techniques and discusses their application to real problems in ways accessible and beneficial to practitioners across several areas—from science and engineering, to medicine, academia and commerce. Includes input by practitioners for practitioners Includes tutorials in numerous fields of study that provide step-by-step instruction on how to use supplied tools to build models Contains practical advice from successful real-world implementations Brings together, in a single resource, all the information a beginner needs to understand the tools and issues in data mining to build successful data mining solutions Features clear, intuitive explanations of novel analytical tools and techniques, and their practical applications




Data Analysis for Omic Sciences: Methods and Applications


Book Description

Data Analysis for Omic Sciences: Methods and Applications, Volume 82, shows how these types of challenging datasets can be analyzed. Examples of applications in real environmental, clinical and food analysis cases help readers disseminate these approaches. Chapters of note include an Introduction to Data Analysis Relevance in the Omics Era, Omics Experimental Design and Data Acquisition, Microarrays Data, Analysis of High-Throughput RNA Sequencing Data, Analysis of High-Throughput DNA Bisulfite Sequencing Data, Data Quality Assessment in Untargeted LC-MS Metabolomic, Data Normalization and Scaling, Metabolomics Data Preprocessing, and more. Presents the best reference book for omics data analysis Provides a review of the latest trends in transcriptomics and metabolomics data analysis tools Includes examples of applications in research fields, such as environmental, biomedical and food analysis




Big and Complex Data Analysis


Book Description

This volume conveys some of the surprises, puzzles and success stories in high-dimensional and complex data analysis and related fields. Its peer-reviewed contributions showcase recent advances in variable selection, estimation and prediction strategies for a host of useful models, as well as essential new developments in the field. The continued and rapid advancement of modern technology now allows scientists to collect data of increasingly unprecedented size and complexity. Examples include epigenomic data, genomic data, proteomic data, high-resolution image data, high-frequency financial data, functional and longitudinal data, and network data. Simultaneous variable selection and estimation is one of the key statistical problems involved in analyzing such big and complex data. The purpose of this book is to stimulate research and foster interaction between researchers in the area of high-dimensional data analysis. More concretely, its goals are to: 1) highlight and expand the breadth of existing methods in big data and high-dimensional data analysis and their potential for the advancement of both the mathematical and statistical sciences; 2) identify important directions for future research in the theory of regularization methods, in algorithmic development, and in methodologies for different application areas; and 3) facilitate collaboration between theoretical and subject-specific researchers.




Introduction to Statistics and Data Analysis


Book Description

Now in its second edition, this introductory statistics textbook conveys the essential concepts and tools needed to develop and nurture statistical thinking. It presents descriptive, inductive and explorative statistical methods and guides the reader through the process of quantitative data analysis. This revised and extended edition features new chapters on logistic regression, simple random sampling, including bootstrapping, and causal inference. The text is primarily intended for undergraduate students in disciplines such as business administration, the social sciences, medicine, politics, and macroeconomics. It features a wealth of examples, exercises and solutions with computer code in the statistical programming language R, as well as supplementary material that will enable the reader to quickly adapt the methods to their own applications.