Data Analytics for Traditional Chinese Medicine Research


Book Description

This contributed volume explores how data mining, machine learning, and similar statistical techniques can analyze the types of problems arising from Traditional Chinese Medicine (TCM) research. The book focuses on the study of clinical data and the analysis of herbal data. Challenges addressed include diagnosis, prescription analysis, ingredient discoveries, network based mechanism deciphering, pattern-activity relationships, and medical informatics. Each author demonstrates how they made use of machine learning, data mining, statistics and other analytic techniques to resolve their research challenges, how successful if these techniques were applied, any insight noted and how these insights define the most appropriate future work to be carried out. Readers are given an opportunity to understand the complexity of diagnosis and treatment decision, the difficulty of modeling of efficacy in terms of herbs, the identification of constituent compounds in an herb, the relationship between these compounds and biological outcome so that evidence-based predictions can be made. Drawing on a wide range of experienced contributors, Data Analytics for Traditional Chinese Medicine Research is a valuable reference for professionals and researchers working in health informatics and data mining. The techniques are also useful for biostatisticians and health practitioners interested in traditional medicine and data analytics.




Modern Computational Approaches to Traditional Chinese Medicine


Book Description

Recognized as an essential component of Chinese culture, Traditional Chinese Medicine (TCM) is both an ancient medical system and one still used widely in China today. TCM's independently evolved knowledge system is expressed mainly in the Chinese language and the information is frequently only available through ancient classics and confidential family records, making it difficult to utilize. The major concern in TCM is how to consolidate and integrate the data, enabling efficient retrieval and discovery of novel knowledge from the dispersed data. Computational approaches such as data mining, semantic reasoning and computational intelligence have emerged as innovative approaches for the reservation and utilization of this knowledge system. Typically, this requires an inter-disciplinary approach involving Chinese culture, computer science, modern healthcare and life sciences. This book examines the computerization of TCM information and knowledge to provide intelligent resources and supporting evidences for clinical decision-making, drug discovery, and education. Recent research results from the Traditional Chinese Medicine Informatics Group of Zhejiang University are presented, gathering in one resource systematic approaches for massive data processing in TCM. These include the utilization of modern Semantic Web and data mining methods for more advanced data integration, data analysis and integrative knowledge discovery. This book will appeal to medical professionals, life sciences students, computer scientists, and those interested in integrative, complementary, and alternative medicine. Interdisciplinary book bringing together Traditional Chinese Medicine and computer scientists Introduces novel network technologies to Traditional Chinese Medicine informatics Provides theory and practical examples and case studies of new techniques




Understanding Traditional Chinese Medicine


Book Description

This volume presents texts written by Austrian and Chinese experts in the field of Traditional Chinese Medicine. The issue the authors worked on is the basic problem how to make a different system of medical thinking plausible for the Western world, especially for Western medicine. This issue is considered from different viewpoints - from the viewpoint of Western medicine that is familiar with Chinese medicine and contrariwise from the viewpoint of Chinese Medicine that is familiar with its Western counterpart and from a philosophical viewpoint. In this way both differences in the theoretical systems of Western and Chinese medicine and problems of adequate translation are profundly discussed.




Research Design in Chinese Medicine


Book Description

Research Design in Chinese Medicine: Linking Social and Health Sciences is an innovative and comprehensive guide that bridges the ancient wisdom of Traditional Chinese Medicine (TCM) with modern research methods in social and health sciences. Authored by an expert with a background in Chinese medicine and a doctorate in education from Johns Hopkins University, this book is set to revolutionize the way TCM is studied and practiced in the contemporary world. Designed for a diverse readership, from TCM students and practitioners to those in social sciences and holistic medicine, the book provides a unique integration of traditional techniques and modern research approaches. It offers invaluable resources for Doctor of Acupuncture and Herbal Medicine (DAHM) students, helping them deepen and refine their research skills. Additionally, it serves as an essential academic tool for educators in TCM and related fields, perfectly suited for course adoption in over 50 accredited acupuncture schools within the U.S. and extending its reach globally. Research Design in Chinese Medicine: Linking Social and Health Sciences offers a balanced emphasis on both qualitative and quantitative research approaches. This holistic methodology ensures that readers gain a full spectrum of knowledge, from formulating research questions to conducting ethical studies. The step-by-step guide provided in the book is supplemented with a wealth of resources, including a dedicated website, downloadable templates, and case studies, making it not just a book but a complete learning experience. The book is positioned to be a key resource in the field of TCM research. Its interdisciplinary approach and practical guidance make it invaluable to anyone looking to conduct meaningful research in TCM. The combination of the author's expertise and the practical tools offered makes this book a must-have for students, practitioners, and researchers in the field.




Traditional Chinese Medicine and Diseases


Book Description

This book focuses on the multi-omics big-data integration, the data-mining techniques and the cutting-edge omics researches in principles and applications for a deep understanding of Traditional Chinese Medicine (TCM) and diseases from the following aspects: (1) Basics about multi-omics data and analytical methods for TCM and diseases. (2) The needs of omics studies in TCM researches, and the basic background of omics research in TCM and disease. (3) Better understanding of the multi-omics big-data integration techniques. (4) Better understanding of the multi-omics big-data mining techniques, as well as with different applications, for most insights from these omics data for TCM and disease researches. (5) TCM preparation quality control for checking both prescribed and unexpected ingredients including biological and chemical ingredients. (6) TCM preparation source tracking. (7) TCM preparation network pharmacology analysis. (8) TCM analysis data resources, web services, and visualizations. (9) TCM geoherbalism examination and authentic TCM identification. Traditional Chinese Medicine has been in existence for several thousands of years, and only in recent tens of years have we realized that the researches on TCM could be profoundly boosted by the omics technologies. Devised as a book on TCM and disease researches in the omics age, this book has put the focus on data integration and data mining methods for multi-omics researches, which will be explained in detail and with supportive examples the “What”, “Why” and “How” of omics on TCM related researches. It is an attempt to bridge the gap between TCM related multi-omics big data, and the data-mining techniques, for best practice of contemporary bioinformatics and in-depth insights on the TCM related questions.




Quantitative Methods for Traditional Chinese Medicine Development


Book Description

In recent years, many pharmaceutical companies and clinical research organizations have been focusing on the development of traditional Chinese (herbal) medicines (TCMs) as alternatives to treating critical or life-threatening diseases and as pathways to personalized medicine. Quantitative Methods for Traditional Chinese Medicine Development is the first book entirely devoted to the design and analysis of TCM development from a Western perspective, i.e., evidence-based clinical research and development. The book provides not only a comprehensive summary of innovative quantitative methods for developing TCMs but also a useful desk reference for principal investigators involved in personalized medicine. Written by one of the world's most prominent biostatistics researchers, the book connects the pharmaceutical industry, regulatory agencies, and academia. It presents a state-of-the-art examination of the subject for: Scientists and researchers who are engaged in pharmaceutical/clinical research and development of TCMs Those in regulatory agencies who make decisions in the review and approval process of TCM regulatory submissions Biostatisticians who provide statistical support to assess clinical safety and effectiveness of TCMs and related issues regarding quality control and assurance as well as to test for consistency in the manufacturing processes for TCMs This book covers all of the statistical issues encountered at various stages of pharmaceutical/clinical development of a TCM. It explains regulatory requirements; product specifications and standards; and various statistical techniques for evaluation of TCMs, validation of diagnostic procedures, and testing consistency




Evidence-based Research Methods for Chinese Medicine


Book Description

This book is a practical guide to the evidence-based medicine (EBM) research methods that are applicable to Chinese medicine (CM). It includes 3 parts: clinical research, healthcare data research and laboratory research. In each chapter, it explains how to acquire, analyze and evaluate a specific kind of CM research result. Authors exemplify the most important methods with successful cases in transforming reliable data into new knowledge of CM. This book emphasizes the requirements for CM researchers to design and conduct CM studies by following the best available principles, standards and guidelines.




A Guide to Chinese Medicine on the Internet


Book Description

A Guide to Chinese Medicine on the Internet frees readers from having to sift through countless websites to find up-to-date, high quality, reliable information on all types of Chinese medicine. This handy resource provides an introduction to the terms and philosophies of Chinese medicine in addition to an extensive categorized listing of online sites related to Chinese culture and medicine, complete with a brief description of each site's content. Guidelines are provided for searching, cataloging, and evaluating websites concerned with Chinese medicine, based on the author's research and personal experience as a practitioner and user of Chinese medicines.




Traditional Herbal Medicine Research Methods


Book Description

This book introduces the methodology for collection and identification of herbal materials, extraction and isolation of compounds from herbs, in vitro bioassay, in vivo animal test, toxicology, and clinical trials of herbal research. To fully understand and make the best use of herbal medicines requires the close combination of chemistry, biochemistry, biology, pharmacology, and clinical science. Although there are many books about traditional medicines research, they mostly focus on either chemical or pharmacological study results of certain plants. This book, however, covers the systematic study and analysis of herbal medicines in general – including chemical isolation and identification, bioassay and mechanism study, pharmacological experiment, and quality control of the raw plant material and end products.