Biological Data Mining And Its Applications In Healthcare


Book Description

Biologists are stepping up their efforts in understanding the biological processes that underlie disease pathways in the clinical contexts. This has resulted in a flood of biological and clinical data from genomic and protein sequences, DNA microarrays, protein interactions, biomedical images, to disease pathways and electronic health records. To exploit these data for discovering new knowledge that can be translated into clinical applications, there are fundamental data analysis difficulties that have to be overcome. Practical issues such as handling noisy and incomplete data, processing compute-intensive tasks, and integrating various data sources, are new challenges faced by biologists in the post-genome era. This book will cover the fundamentals of state-of-the-art data mining techniques which have been designed to handle such challenging data analysis problems, and demonstrate with real applications how biologists and clinical scientists can employ data mining to enable them to make meaningful observations and discoveries from a wide array of heterogeneous data from molecular biology to pharmaceutical and clinical domains.




Life Science Data Mining


Book Description

This timely book identifies and highlights the latest data mining paradigms to analyze, combine, integrate, model and simulate vast amounts of heterogeneous multi-modal, multi-scale data for emerging real-world applications in life science.The cutting-edge topics presented include bio-surveillance, disease outbreak detection, high throughput bioimaging, drug screening, predictive toxicology, biosensors, and the integration of macro-scale bio-surveillance and environmental data with micro-scale biological data for personalized medicine. This collection of works from leading researchers in the field offers readers an exceptional start in these areas.




Biological Data Mining


Book Description

Like a data-guzzling turbo engine, advanced data mining has been powering post-genome biological studies for two decades. Reflecting this growth, Biological Data Mining presents comprehensive data mining concepts, theories, and applications in current biological and medical research. Each chapter is written by a distinguished team of interdisciplin




Interactive Knowledge Discovery and Data Mining in Biomedical Informatics


Book Description

One of the grand challenges in our digital world are the large, complex and often weakly structured data sets, and massive amounts of unstructured information. This “big data” challenge is most evident in biomedical informatics: the trend towards precision medicine has resulted in an explosion in the amount of generated biomedical data sets. Despite the fact that human experts are very good at pattern recognition in dimensions of = 3; most of the data is high-dimensional, which makes manual analysis often impossible and neither the medical doctor nor the biomedical researcher can memorize all these facts. A synergistic combination of methodologies and approaches of two fields offer ideal conditions towards unraveling these problems: Human–Computer Interaction (HCI) and Knowledge Discovery/Data Mining (KDD), with the goal of supporting human capabilities with machine learning./ppThis state-of-the-art survey is an output of the HCI-KDD expert network and features 19 carefully selected and reviewed papers related to seven hot and promising research areas: Area 1: Data Integration, Data Pre-processing and Data Mapping; Area 2: Data Mining Algorithms; Area 3: Graph-based Data Mining; Area 4: Entropy-Based Data Mining; Area 5: Topological Data Mining; Area 6 Data Visualization and Area 7: Privacy, Data Protection, Safety and Security.




Biological Data Mining in Protein Interaction Networks


Book Description

"The goal of this book is to disseminate research results and best practices from cross-disciplinary researchers and practitioners interested in, and working on bioinformatics, data mining, and proteomics"--Provided by publisher.




Data Mining in Medical and Biological Research


Book Description

This book intends to bring together the most recent advances and applications of data mining research in the promising areas of medicine and biology from around the world. It consists of seventeen chapters, twelve related to medical research and five focused on the biological domain, which describe interesting applications, motivating progress and worthwhile results. We hope that the readers will benefit from this book and consider it as an excellent way to keep pace with the vast and diverse advances of new research efforts.




Biomedical Data Mining for Information Retrieval


Book Description

BIOMEDICAL DATA MINING FOR INFORMATION RETRIEVAL This book not only emphasizes traditional computational techniques, but discusses data mining, biomedical image processing, information retrieval with broad coverage of basic scientific applications. Biomedical Data Mining for Information Retrieval comprehensively covers the topic of mining biomedical text, images and visual features towards information retrieval. Biomedical and health informatics is an emerging field of research at the intersection of information science, computer science, and healthcare and brings tremendous opportunities and challenges due to easily available and abundant biomedical data for further analysis. The aim of healthcare informatics is to ensure the high-quality, efficient healthcare, better treatment and quality of life by analyzing biomedical and healthcare data including patient’s data, electronic health records (EHRs) and lifestyle. Previously, it was a common requirement to have a domain expert to develop a model for biomedical or healthcare; however, recent advancements in representation learning algorithms allows us to automatically to develop the model. Biomedical image mining, a novel research area, due to the vast amount of available biomedical images, increasingly generates and stores digitally. These images are mainly in the form of computed tomography (CT), X-ray, nuclear medicine imaging (PET, SPECT), magnetic resonance imaging (MRI) and ultrasound. Patients’ biomedical images can be digitized using data mining techniques and may help in answering several important and critical questions relating to healthcare. Image mining in medicine can help to uncover new relationships between data and reveal new useful information that can be helpful for doctors in treating their patients. Audience Researchers in various fields including computer science, medical informatics, healthcare IOT, artificial intelligence, machine learning, image processing, clinical big data analytics.




Data Mining in Clinical Medicine


Book Description

This volume complies a set of Data Mining techniques and new applications in real biomedical scenarios. Chapters focus on innovative data mining techniques, biomedical datasets and streams analysis, and real applications. Written in the highly successful Methods in Molecular Biology series format, chapters are thought to show to Medical Doctors and Engineers the new trends and techniques that are being applied to Clinical Medicine with the arrival of new Information and Communication technologies Authoritative and practical, Data Mining in Clinical Medicine seeks to aid scientists with new approaches and trends in the field.




Data Mining in Biomedicine


Book Description

This volume presents an extensive collection of contributions covering aspects of the exciting and important research field of data mining techniques in biomedicine. Coverage includes new approaches for the analysis of biomedical data; applications of data mining techniques to real-life problems in medical practice; comprehensive reviews of recent trends in the field. The book addresses incorporation of data mining in fundamental areas of biomedical research: genomics, proteomics, protein characterization, and neuroscience.




Data Mining in Biomedical Imaging, Signaling, and Systems


Book Description

Data mining can help pinpoint hidden information in medical data and accurately differentiate pathological from normal data. It can help to extract hidden features from patient groups and disease states and can aid in automated decision making. Data Mining in Biomedical Imaging, Signaling, and Systems provides an in-depth examination of the biomedical and clinical applications of data mining. It supplies examples of frequently encountered heterogeneous data modalities and details the applicability of data mining approaches used to address the computational challenges in analyzing complex data. The book details feature extraction techniques and covers several critical feature descriptors. As machine learning is employed in many diagnostic applications, it covers the fundamentals, evaluation measures, and challenges of supervised and unsupervised learning methods. Both feature extraction and supervised learning are discussed as they apply to seizure-related patterns in epilepsy patients. Other specific disorders are also examined with regard to the value of data mining for refining clinical diagnoses, including depression and recurring migraines. The diagnosis and grading of the world’s fourth most serious health threat, depression, and analysis of acoustic properties that can distinguish depressed speech from normal are also described. Although a migraine is a complex neurological disorder, the text demonstrates how metabonomics can be effectively applied to clinical practice. The authors review alignment-based clustering approaches, techniques for automatic analysis of biofilm images, and applications of medical text mining, including text classification applied to medical reports. The identification and classification of two life-threatening heart abnormalities, arrhythmia and ischemia, are addressed, and a unique segmentation method for mining a 3-D imaging biomarker, exemplified by evaluation of osteoarthritis, is also presented. Given the widespread deployment of complex biomedical systems, the authors discuss system-engineering principles in a proposal for a design of reliable systems. This comprehensive volume demonstrates the broad scope of uses for data mining and includes detailed strategies and methodologies for analyzing data from biomedical images, signals, and systems.