Author : Hongbo Zhai
Publisher : CRC Press
Page : 1232 pages
File Size : 29,3 MB
Release : 2004-02-25
Category : Medical
ISBN : 0203426274
For twenty-five years, Dermatotoxicology has stood as the definitive reference book in the field. A generation of toxicologists and dermatologists has consulted this volume throughout their careers, finding within it a wealth of theoretical and practical guidance. Updated and expanded to reflect the latest developments in skin toxicology, De
Author : Klaus Peter Wilhelm
Publisher : CRC Press
Page : 1044 pages
File Size : 42,42 MB
Release : 2007-11-26
Category : Medical
ISBN : 142000977X
Reflecting the embryonic state of the field, the first edition of Dermatoxicology, published in 1977, numbered 567 pages. Now the foundational reference in dermal toxicology, this seventh edition consists of 1,032 pages and defines what was once a largely intuitive field but has evolved into an established science of metrics and mechanisms. Updated
Author : Francis Nicholas Marzulli
Publisher : CRC Press
Page : 1960 pages
File Size : 26,96 MB
Release : 1991-06-01
Category : Medical
ISBN : 9781560320555
A guide to the field of dermatotoxicology. This edition includes fundamental information on the mechanisms of action of toxic substances on skin as well as practical information on the varied responses of skin to specific toxic substances and approaches to evaluating dermal toxicity. Other topics discussed include: hostile natural elements, such as ultraviolet radiation, poisonous plants, man-made detergents and chemicals; problems associated with chronic occupational skin exposure to toxic chemicals; animal alternative research programmes; carcinogenic and Photo Carcinogenic Potential Of Xenobiotic Chemicals; Oculotoxicity; Risk assessment and management; and cosmetic safety. Anatomical factors affecting barrier functions/ lipids of the permeability barrier/the skin immune system.
Author : Howard I. Maibach
Publisher : Academic Press
Page : 150 pages
File Size : 45,54 MB
Release : 2014-06-24
Category : Science
ISBN : 0124201997
Applied Dermatotoxicology: Clinical Aspects provides concise, systematic, and state-of-the-art information on the toxicological effects of substances on skin, and recent advances in dermal toxicity testing. This book specifically addresses the clinical presentations borne out of exposure to a variety of chemicals. It begins with an overview of skin biology to provide toxicologists with a basic understanding of its anatomy and physiology. Next it presents a variety of dermatotoxicological effects, as well at the toxic agents that cause them, with color photographs to illustrate these effects. Applied Dermatotoxicology: Clinical Aspects is an essential reference for toxicologists in industry, and for those medical professionals who encounter cases of dermal exposure to toxic agents. - A concise, yet inclusive review of effects of chemical exposure - Includes background on basic skin biology - Provides vital clinical reference for toxicologists in non-clinical settings
Author : Francis N. Marzulli
Publisher : CRC Press
Page : 581 pages
File Size : 17,75 MB
Release : 2019-05-07
Category : Medical
ISBN : 0429526105
This work presents and evaluates methods employed to identify the potential of certain types of chemicals to adversely affect the skin. A variety of test methods are included such as tests for skin penetration, metabolism, irritation, the skin immune system, photo effects, skin cancer, and topical effects of retinoids and depigmenting chemicals. Tests for chemicals that affect the reproductive and nervous system are also included. Both animal and human tests that have been standardised and tests that are under development and employ animal alternatives are addressed in this book. Besides different testing methods, a rationale for accepting non-animal models and a review of some regulatory agency discussions about animal alternative tests are included.
Author : Francis Nicholas Marzulli
Publisher :
Page : 812 pages
File Size : 16,77 MB
Release : 1987
Category : Medical
ISBN :
The most recent edition of the classic reference text contains 47 chapters on the mechanisms of toxicants on the skin, and related issues. The first part of the book provides background information and basic concepts of dermatotoxicology, and the second part covers methodologies employed to discern toxic effects. Some of the featured topics include: light induced dermal toxicity, problems associated with chronic occupational skin exposure to toxic chemicals, animal rights and animal research, and cosmetics safety. Annotation copyright by Book News, Inc., Portland, OR
Author : Francis Nicholas Marzulli
Publisher : Hemisphere Pub
Page : 604 pages
File Size : 29,58 MB
Release : 1977
Category : Medical
ISBN :
Author : S. Schliemann
Publisher : Karger Medical and Scientific Publishers
Page : 191 pages
File Size : 38,53 MB
Release : 2007-01-01
Category : Medical
ISBN : 3805582188
The differential application of skin protection in occupational settings becomes increasingly complex. Due to new scientific results and technological aspects as well as European and US regulations that have to be considered in the context of cosmetics and personal protective equipment, the practical application of skin protection requires constant reviewing and improvement. This publication provides a comprehensive update on specific cosmetic products from general principles of composition, protection from specific exposures, such as irritants, allergens and ultraviolet irradiation, to safety and efficacy testing both from the perspective of in vitro and in vivo testing. The second part focusses on special requirements and practical application in high-risk occupations and the respective skin protection programs, also including some critical remarks on the limitations of currently available skin protection measures. For specialists in the field of occupational dermatology such as dermatologists, allergists, occupational physicians, industrial hygienists, toxicologists, pharmacists and cosmetic scientists, this volume provides essential information on practical application, recommendation, testing or the making of personal skin protection products.
Author : Robert Chilcott
Publisher : John Wiley & Sons
Page : 392 pages
File Size : 26,12 MB
Release : 2008-07-31
Category : Science
ISBN : 0470773081
Written by authorities in the field, this book provides a “bottom up” approach to studying skin toxicology. Principles and Practice of Skin Toxicology clearly outlines basic concepts, cites historical and modern references and contains a dictionary for easy reference. The inclusion of global legislation and regulatory aspects on the topic makes this a comprehensive review for every practitioner, clinical researcher in industry and academia, and MSc and PhD student of toxicology. Different sections cover skin structure and function, principles and measurement of skin absorption, clinical aspects of dermal toxicity and in vitro alternatives. A section on regulatory and legislative aspects includes case studies from the UK that fulfill European Union and US FDA requirements. A glossary provides definitions of technical terms, and the chapters contain an introduction, learning boxes and summary section for ease of use. Includes a chapter on drug delivery through the skin. Addresses risk assessment: a key area for the interpretation of skin absorption data that is rarely covered.
Author : Kenneth A. Walters
Publisher : CRC Press
Page : 592 pages
File Size : 37,71 MB
Release : 2002-02-20
Category : Medical
ISBN : 0824743237
Containing 350 illustrations, tables, and equations and covering AAPS/FDA guidelines for the experimentation and analysis of in vivo and in vitro percutaneous absorption, this reference provides comprehensive coverage of the development, preparation, and application of topical and transdermal therapeutic systems. Recognized international experts di
