Design Sensitivity


Book Description

All researchers face an important challenge - designing research that will have sufficient sensitivity to detect those effects it purports to investigate. Through careful explanations and selection of examples, this title examines the concept of design sensitivity and explains statistical power and the elements that determine it.




Design Sensitivity Analysis of Structural Systems


Book Description

The book is organized into four chapters. The first three treat distinct types of design variables, and the fourth presents a built-up structure formulation that combines the other three. The first chapter treats finite-dimensional problems, in which the state variable is a finite-dimensional vector of structure displacements and the design parameters. The structual state equations are matrix equations for static response, vibration, and buckling of structures and matrix differential equations for transient dynamic response of structures, which design variables appearing in the coefficient matrices.




Design Sensitivity Analysis


Book Description

This book provides an understandable introduction to one approach to design sensitivity computation and illustrates some of the important mathematical and computational issues inherent in using the sensitivity equation method (SEM) for partial differential equations. The authors use basic models to illustrate the computational issues that one might encounter when applying the SEM in a laboratory or research setting, while providing an overview of applications and computational issues regarding sensitivity calculations performed by way of continuous sensitivity equation methods (CSEM).




Value Sensitive Design


Book Description

Using our moral and technical imaginations to create responsible innovations: theory, method, and applications for value sensitive design. Implantable medical devices and human dignity. Private and secure access to information. Engineering projects that transform the Earth. Multigenerational information systems for international justice. How should designers, engineers, architects, policy makers, and others design such technology? Who should be involved and what values are implicated? In Value Sensitive Design, Batya Friedman and David Hendry describe how both moral and technical imagination can be brought to bear on the design of technology. With value sensitive design, under development for more than two decades, Friedman and Hendry bring together theory, methods, and applications for a design process that engages human values at every stage. After presenting the theoretical foundations of value sensitive design, which lead to a deep rethinking of technical design, Friedman and Hendry explain seventeen methods, including stakeholder analysis, value scenarios, and multilifespan timelines. Following this, experts from ten application domains report on value sensitive design practice. Finally, Friedman and Hendry explore such open questions as the need for deeper investigation of indirect stakeholders and further method development. This definitive account of the state of the art in value sensitive design is an essential resource for designers and researchers working in academia and industry, students in design and computer science, and anyone working at the intersection of technology and society.




Structural Sensitivity Analysis and Optimization 2


Book Description

Extensive numerical methods for computing design sensitivity are included in the text for practical application and software development. The numerical method allows integration of CAD-FEA-DSA software tools, so that design optimization can be carried out using CAD geometric models instead of FEA models. This capability allows integration of CAD-CAE-CAM so that optimized designs can be manufactured effectively.




Structural Sensitivity Analysis and Optimization 1


Book Description

Extensive numerical methods for computing design sensitivity are included in the text for practical application and software development. The numerical method allows integration of CAD-FEA-DSA software tools, so that design optimization can be carried out using CAD geometric models instead of FEA models. This capability allows integration of CAD-CAE-CAM so that optimized designs can be manufactured effectively.




Design of Observational Studies


Book Description

An observational study is an empiric investigation of effects caused by treatments when randomized experimentation is unethical or infeasible. Observational studies are common in most fields that study the effects of treatments on people, including medicine, economics, epidemiology, education, psychology, political science and sociology. The quality and strength of evidence provided by an observational study is determined largely by its design. Design of Observational Studies is both an introduction to statistical inference in observational studies and a detailed discussion of the principles that guide the design of observational studies. Design of Observational Studies is divided into four parts. Chapters 2, 3, and 5 of Part I cover concisely, in about one hundred pages, many of the ideas discussed in Rosenbaum’s Observational Studies (also published by Springer) but in a less technical fashion. Part II discusses the practical aspects of using propensity scores and other tools to create a matched comparison that balances many covariates. Part II includes a chapter on matching in R. In Part III, the concept of design sensitivity is used to appraise the relative ability of competing designs to distinguish treatment effects from biases due to unmeasured covariates. Part IV discusses planning the analysis of an observational study, with particular reference to Sir Ronald Fisher’s striking advice for observational studies, "make your theories elaborate." The second edition of his book, Observational Studies, was published by Springer in 2002.




Research Handbook on Design Law


Book Description

Written by expert scholars and practitioners, this unique Research Handbook presents the state of the art in research on, and the practice of, international design law. Combining cutting-edge research with a practical approach, it examines key trends and covers key cases, regional and national laws, as well as concepts of international design protection. In particular, the U.S. framework is compared with the regime of the EU, and issues relating to the Hague Agreement are also covered.




Developing a Protocol for Observational Comparative Effectiveness Research: A User's Guide


Book Description

This User’s Guide is a resource for investigators and stakeholders who develop and review observational comparative effectiveness research protocols. It explains how to (1) identify key considerations and best practices for research design; (2) build a protocol based on these standards and best practices; and (3) judge the adequacy and completeness of a protocol. Eleven chapters cover all aspects of research design, including: developing study objectives, defining and refining study questions, addressing the heterogeneity of treatment effect, characterizing exposure, selecting a comparator, defining and measuring outcomes, and identifying optimal data sources. Checklists of guidance and key considerations for protocols are provided at the end of each chapter. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews. More more information, please consult the Agency website: www.effectivehealthcare.ahrq.gov)




The CRC Handbook of Mechanical Engineering


Book Description

The second edition of this standard-setting handbook provides and all-encompassing reference for the practicing engineer in industry, government, and academia, with relevant background and up-to-date information on the most important topics of modern mechanical engineering. These topics include modern manufacturing and design, robotics, computer engineering, environmental engineering, economics, patent law, and communication/information systems. The final chapter and appendix provide information regarding physical properties and mathematical and computational methods. New topics include nanotechnology, MEMS, electronic packaging, global climate change, electric and hybrid vehicles, and bioengineering.