MRI-Guided Focused Ultrasound Surgery


Book Description

MRI-Guided Focused Ultrasound Surgery will be the first publication on this new technology, and will present a variety of current and future clinical applications in tumor ablation treatment. This source helps surgeons and specialists evaluate, analyze, and utilize MRI-guided focused ultrasound surgery - bridging the gap between phase 3 clinical tr




Biomedical Technology and Devices, Second Edition


Book Description

Biomedical Technology and Devices, Second Edition focuses on the equipment, devices, and techniques used in modern medicine to diagnose, treat, and monitor human illnesses. Gathering together and compiling the latest information available on medical technology, this revised work adds ten new chapters. It starts with the basics, introducing the history of the thermometer and measuring body temperature, before moving on to a medley of devices that are far more complex. This book explores diverse technological functions and procedures including signal processing, auditory systems, magnetic resonance imaging, ultrasonic and emission imaging, image-guided thermal therapy, medical robotics, shape memory alloys, biophotonics, and tissue engineering. Each chapter offers a description of the technique, its technical considerations, and its use according to its applications and relevant body systems. It can be used as a professional resource, as well as a textbook for undergraduate and graduate students.




Diagnostic Ultrasound Imaging: Inside Out


Book Description

Diagnostic Ultrasound Imaging provides a unified description of the physical principles of ultrasound imaging, signal processing, systems and measurements. This comprehensive reference is a core resource for both graduate students and engineers in medical ultrasound research and design. With continuing rapid technological development of ultrasound in medical diagnosis, it is a critical subject for biomedical engineers, clinical and healthcare engineers and practitioners, medical physicists, and related professionals in the fields of signal and image processing. The book contains 17 new and updated chapters covering the fundamentals and latest advances in the area, and includes four appendices, 450 figures (60 available in color on the companion website), and almost 1,500 references. In addition to the continual influx of readers entering the field of ultrasound worldwide who need the broad grounding in the core technologies of ultrasound, this book provides those already working in these areas with clear and comprehensive expositions of these key new topics as well as introductions to state-of-the-art innovations in this field. - Enables practicing engineers, students and clinical professionals to understand the essential physics and signal processing techniques behind modern imaging systems as well as introducing the latest developments that will shape medical ultrasound in the future - Suitable for both newcomers and experienced readers, the practical, progressively organized applied approach is supported by hands-on MATLAB® code and worked examples that enable readers to understand the principles underlying diagnostic and therapeutic ultrasound - Covers the new important developments in the use of medical ultrasound: elastography and high-intensity therapeutic ultrasound. Many new developments are comprehensively reviewed and explained, including aberration correction, acoustic measurements, acoustic radiation force imaging, alternate imaging architectures, bioeffects: diagnostic to therapeutic, Fourier transform imaging, multimode imaging, plane wave compounding, research platforms, synthetic aperture, vector Doppler, transient shear wave elastography, ultrafast imaging and Doppler, functional ultrasound and viscoelastic models




Image-Guided Cancer Therapy


Book Description

Image-Guided Cancer Therapy: A Multidisciplinary Approach provides clinicians with in-depth coverage of the growing, dynamic field of interventional oncology. Combining the knowledge of expert editors and authors into one powerhouse reference, this book looks at tumor ablation, HIFU, embolic therapies, emerging technologies, and radiation therapy throughout the body (liver, bone, breast, gynecologic and prostate cancers, to name just a few) , and includes discussion of different imaging modalities. In the words of Peter Mueller, MD, author of the book’s Foreword: “... The senior authors are all world renowned experts in interventional oncology, which is another example of the high quality authorship and experience that is brought to this book. The later chapters discuss therapies that are simply not covered in any other source. Everyone who is doing or wants to do ablation therapies and interventional oncology will face a time when they will be asked to use their expertise in less used and less investigated areas. There is nowhere else where the reader can get information on the prostate, breast, and gynecologic areas, and especially pediatrics....This book is an outstanding contribution to the literature and will become a ‘must read’ for all physicians who are interested in Interventional Oncology.”




Principles and Applications of Therapeutic Ultrasound in Healthcare


Book Description

Principles and Applications of Therapeutic Ultrasound in Healthcare introduces concepts, principles, construction, and applications of therapeutic ultrasound: from bench to bedside. A comprehensive examination of the industry and medical application of ultrasound therapy, this book highlights working principles, research progress, and system




Theranostics and Image Guided Drug Delivery


Book Description

Molecular imaging of drugs or drug carriers is a valuable tool that can provide important information on spatiotemporal distribution of drugs, allowing improved drug distribution at target sites. Chemically labelled drugs can be used to both diagnose and treat diseases. This book introduces the topic of image guided drug delivery and covers the latest imaging techniques and developments in theranostics, highlighting the interdisciplinary nature of this field as well as its translational ability. These technologies and techniques hold potential for individualised, safer therapies. The book introduces the chemistry behind labelling drugs or drug carriers for imaging. It then discusses current scientific progress in the discovery and development of theranostic agents as well as the latest advances in triggered drug delivery. Novel imaging techniques that can be combined with therapeutics are presented, as well as results and findings from early clinical trials. This text will provide postgraduates and researchers in various disciplines associated with drug discovery, including chemistry, device engineering, oncology, neurology, cardiology, imaging, and nanoscience, an overview of this important field where several disciplines have been combined to improve treatments. Readers will be introduced to techniques that can be translated to the clinic and be applied widely.




Image-guided Focused Ultrasound Therapy


Book Description

Ultrasound has been widely used in diagnostic imaging for a long time. In the past 10 years, image-guided focused ultrasound therapy has seen rapid growth, in biomedical science and engineering, and in clinical medicine. The purpose of this book is to bring internationally renowned authorities and experts in this field together to provide up-to-date and comprehensive reviews of basic physics, biomedical engineering, and clinical applications of focused ultrasound therapy in a widely accessible fashion. Focusing on applications in cancer treatment, this book covers basic principles, practical aspects, and clinical applications of focused ultrasound therapy. It reviews the medical physics and bio-effects of focused ultrasound beams on living tissues, dosimetric methods and measurements, transducer engineering, image guidance and monitoring (including magnetic resonance imaging -- MRI -- and ultrasound), treatment delivery systems, and clinical applications. The book also gives practical guidelines on patient setup, target localisation, treatment planning and image-guided procedures for the treatment in various sites, including the prostate, liver, pancreas, breast, kidney, uterus, bone, and brain. The book discusses major challenges for the use of focused ultrasound energy on living tissues and explores the cellular and physiological responses that can be employed in the fight against cancer from biological, physics and engineering perspectives. It also highlights recent advances, including the treatment of solid tumours using image-guided drug delivery, and the exploitation of microbubbles, nanoparticles, and other cutting-edge techniques. Readers who are interested in learning more about the technique and the clinical applications described in each chapter can find more information in the comprehensive bibliographies provided. This book is suitable for anyone involved in, or looking to become involved in, the research and clinical applications of focused ultrasound therapy, including medical professionals, physicists, biomedical engineers, graduate students and others working in this multidisciplinary field. It offers a balanced and critical assessment of state-of-the-art technologies, major challenges, and an outlook on the future of focused ultrasound therapy. It presents a thorough introduction for those new to the field while providing helpful, up-to-date information and guidelines for readers already using this therapy in clinical and pre-clinical settings. Key Features: Brings together a wide range of world-leading experts in this new field, presenting the latest clinical outcomes of using focused ultrasound for the treatment of benign and malignant diseases Covers the fundamental physics of focused ultrasound therapy and ultrasound-mediated drug delivery, including chapters on the mechanism of sonoporation, microbubble and ultrasound interaction, and their potential clinical applications Introduces clinical guidelines for focused ultrasound therapy, including indications and contraindications, treatment goals, the selection of patients, clinical observation during treatment procedure and follow-up, and characteristics of image changes after treatment




DeVita, Hellman, and Rosenberg's Cancer


Book Description

Presenting comprehensive, cutting-edge information on the science of oncology and the multimodality treatment of every cancer type, this eighth edition--now in full color--contains more than 40 brand-new chapters, and more than 70 chapters have been rewritten by new contributing authors.




Emerging Therapeutic Ultrasound


Book Description

With contributions by internationally re-knowned authorities and experts in the field of ultrasonic imaging, this book provides comprehensive reviews on basic physical principles and applications of emerging and rapidly developing therapeutic techniques.In specific, reviews of mechanisms for bioeffects of ultrasound relevant to therapeutic applications, high intensity focused ultrasound and its application in surgery, ultrasound assisted target drug and gene delivery, as well as transdermal drug delivery are discussed.The book will be a useful reference source for graduate students, academics and researchers.




The Tumor


Book Description

John Grisham says THE TUMOR is the most important book he has ever written. In this short book, he provides readers with a fictional account of how a real, new medical technology could revolutionize the future of medicine by curing with sound. THE TUMOR follows the present day experience of the fictional patient Paul, an otherwise healthy 35-year-old father who is diagnosed with a malignant brain tumor. Grisham takes readers through a detailed account of Paul’s treatment and his family’s experience that doesn’t end as we would hope. Grisham then explores an alternate future, where Paul is diagnosed with the same brain tumor at the same age, but in the year 2025, when a treatment called focused ultrasound is able to extend his life expectancy. Focused ultrasound has the potential to treat not just brain tumors, but many other disorders, including Parkinson’s, Alzheimer’s, hypertension, and prostate, breast and pancreatic cancer. For more information or to order a free hardcopy of the book, please visit The Focused Ultrasound Foundation’s website www.fusfoundation.org. Here you will find a video of Grisham on the TEDx stage with the Foundation’s chairman and a Parkinson’s patient who brings the audience to its feet sharing her incredible story of a focused ultrasound “miracle.” Readers will get a taste of the narrative they expect from Grisham, but this short book will also educate and inspire people to be hopeful about the future of medical innovation.