Author : Yong Xiao
Publisher : Frontiers Media SA
Page : 175 pages
File Size : 28,62 MB
Release : 2022-11-23
Category : Science
ISBN : 2832506941
Author : Yuan-Ming Zhang
Publisher : Frontiers Media SA
Page : 236 pages
File Size : 41,63 MB
Release : 2019-06-19
Category :
ISBN : 2889458342
Genome-Wide Association Studies (GWAS) are widely used in the genetic dissection of complex traits. Most existing methods are based on single-marker association in genome-wide scans with population structure and polygenic background controls. To control the false positive rate, the Bonferroni correction for multiple tests is frequently adopted. This stringent correction results in the exclusion of important loci, especially for GWAS in crop genetics. To address this issue, multi-locus GWAS methodologies have been recommended, i.e., FASTmrEMMA, ISIS EM-BLASSO, mrMLM, FASTmrMLM, pLARmEB, pKWmEB and FarmCPU. In this Research Topic, our purpose is to clarify some important issues in the application of multi-locus GWAS methods. Here we discuss the following subjects: First, we discuss the advantages of new multi-locus GWAS methods over the widely-used single-locus GWAS methods in the genetic dissection of complex traits, metabolites and gene expression levels. Secondly, large experiment error in the field measurement of phenotypic values for complex traits in crop genetics results in relatively large P-values in GWAS, indicating the existence of small number of significantly associated SNPs. To solve this issue, a less stringent P-value critical value is often adopted, i.e., 0.001, 0.0001 and 1/m (m is the number of markers). Although lowering the stringency with which an association is made could identify more hits, confidence in these hits would significantly drop. In this Research Topic we propose a new threshold of significant QTN (LOD=3.0 or P-value=2.0e-4) in multi-locus GWAS to balance high power and low false positive rate. Thirdly, heritability missing in GWAS is a common phenomenon, and a series of scientists have explained the reasons why the heritability is missing. In this Research Topic, we also add one additional reason and propose the joint use of several GWAS methodologies to capture more QTNs. Thus, overall estimated heritability would be increased. Finally, we discuss how to select and use these multi-locus GWAS methods.
Author : Rachid Serraj
Publisher : World Scientific
Page : 409 pages
File Size : 43,1 MB
Release : 2009-07-15
Category : Technology & Engineering
ISBN : 9814467383
The success of the Green Revolution in closing the gap between world population and food production was principally achieved by increasing crop productivity in favorable areas. However, this success has been limited in the rainfed systems, which are prone to frequent droughts and other abiotic stresses. Worldwide, drought affects approximately 23 million hectares of rainfed rice. Varieties combining improved drought resistance with high yield under favorable conditions and quality characteristics preferred by farmers are the most promising and deliverable technologies for alleviating poverty in communities dependent on rainfed rice production.This book describes some of the recent advances in the genetics and physiology of drought resistant rice varieties and the integration of highly efficient breeding and genetic analysis techniques with functional genomics. Harnessing recent scientific breakthroughs, Drought Frontiers Project (seeds.irri.org/drought) is launched as a major assault on the problem of improving drought resistance in rice. Featuring contributions from leading international experts, case studies are discussed to present perspectives on the various multidisciplinary facets of drought resistance in rice, along with the involvement of natural resource management practices and the socioeconomic implications that entail. Readers will be better informed of this highly relevant and complex topic of improving rice drought resistance in a global environment characterized by increased water scarcity./a
Author : Bozzano G Luisa
Publisher : Elsevier
Page : 441 pages
File Size : 48,81 MB
Release : 2012-12-02
Category : Technology & Engineering
ISBN : 008098438X
Lipids in Cereal Technology provides a comprehensive review of cereal lipids and their role in cereal processing and products. Topics range from acyl lipids and non-saponifiable lipids in cereals, such as barley and maize, to lipid metabolism in germinating cereals, physical state of lipids and their technical effects in baking, the effect of storage on the lipids and breadmaking properties of wheat flour, and lipids in pasta and pasta processing. Organized into 19 chapters, this review brings together the knowledge and experience of an international group of experts. It begins with an overview of the fundamental aspects of cereal grain lipids and enzymes. It then discusses the specific cereals, processing, and cereal products. Moreover, the book explains the composition and distribution of lipids in the grain, the biochemical changes that occur when the grain germinates, and the biochemistry of the enzymes involved in lipid degradation. Some chapters focus on wheat and the significance of lipids in milling, flour storage, baking, and pasta manufacture. Other chapters consider individual cereals such as rice, oats, maize, malt, and barley along with corn oil, wheat germ oil, and other cereal products.
Author : Reyazul Rouf Mir
Publisher : Frontiers Media SA
Page : 255 pages
File Size : 46,62 MB
Release : 2021-03-22
Category : Medical
ISBN : 2889666115
Author : Michael I. Gurr
Publisher : John Wiley & Sons
Page : 446 pages
File Size : 15,62 MB
Release : 2016-08-29
Category : Science
ISBN : 1118501136
For the 6th Edition of this highly regarded textbook devoted to lipids, the title has been modified from Lipid Biochemistry to Lipids to acknowledge the coming together of biological and medical sciences, the increasingly blurred boundaries between them and the growing importance of lipids in diverse aspects of science and technology. The principal aims of this new edition - to inform students and researchers about lipids, to assist teachers and encourage further research – have not changed since previous editions. Significant advances in lipid science have demanded yet another extensive rewriting for this edition, with the addition of two new authors, to cover new knowledge of genes coding for proteins involved in lipid metabolism, the many lipids involved in cell signalling, the roles of lipids in health and disease and new developments in biotechnology in support of agriculture and industry. An introductory chapter summarizes the types of lipids covered and their identification and provides a guide to the contents. Chapters contain boxes illustrating special topics, key point summaries and suggested further reading. Lipids: Sixth Edition provides a huge wealth of information for upper-level students of biological and clinical sciences, food science and nutrition, and for professionals working in academic and industrial research. Libraries in all universities and research establishments where biological, medical and food and nutritional sciences are studied and taught should have copies of this excellent and comprehensive new edition on their shelves.
Author : Linghe Zeng
Publisher : Frontiers Media SA
Page : 297 pages
File Size : 17,71 MB
Release : 2022-11-07
Category : Science
ISBN : 2832501109
Author : Henry T. Nguyen
Publisher : Springer
Page : 216 pages
File Size : 41,94 MB
Release : 2017-09-20
Category : Science
ISBN : 3319641980
This book examines the application of soybean genome sequences to comparative, structural, and functional genomics. Since the availability of the soybean genome sequence has revolutionized molecular research on this important crop species, the book also describes how the genome sequence has shaped research on transposon biology and applications for gene identification, tilling and positional gene cloning. Further, the book shows how the genome sequence influences research in the areas of genetic mapping, marker development, and genome-wide association mapping for identifying important trait genes and soybean breeding. In closing, the economic and botanical aspects of the soybean are also addressed.
Author : Johann Vollmann
Publisher : Springer Science & Business Media
Page : 557 pages
File Size : 48,49 MB
Release : 2009-09-18
Category : Science
ISBN : 0387775943
When one is privileged to participate long enough in a professional capacity, certain trends may be observed in the dynamics of how challenges are met or how problems are solved. Agricultural research is no exception in view of how the plant sciences have moved forward in the past 30 years. For example, the once grand but now nearly forgotten art of whole plant physiology has given way almost completely to the more sophisticated realm of molecular biology. What once was the American Society of Plant Physiologists’ is now the American Society of Plant Molecular Biology; a democratic decision to indemnify efforts to go beyond the limits of the classical science and actually begin to understand the underlying biological basis for genetic regulation of metabolic mechanisms in plants. Yet, as new technologies open windows of light on the inner workings of biological processes, one might reminisce with faint nostalgia on days long past when the artisans of plant physiology, biochemistry, analytical chemistry and other scientific disciplines ebbed and waned in prominence. No intentional reference is made here regarding Darwinism; the plant sciences always have been extremely competitive. Technology is pivotal. Those who develop and/or implement innovative concepts typically are regarded as leaders in their respective fields. Each positive incremental step helps bring recognition and the impetus to push a scientific discipline forward with timely approaches to address relevant opportunities.
Author : Ting Peng
Publisher : Frontiers Media SA
Page : 307 pages
File Size : 35,29 MB
Release : 2024-06-13
Category : Science
ISBN : 2832550355
Global climate change, reductions in arable land, and food security demands that plant breeding will continue to play an imperative role in feeding 9 billion people sustainably by 2050. In order to face this challenge, modern plant breeding will necessitate the adoption of new technologies and practices to boost production of cultivated plants by capturing or generating more favorable genetic diversity. In crop plants, the majority of agronomically important traits are quantitatively inherited, controlled by multiple genes each with a small effect (quantitative trait loci, QTLs). The most common approach to pre-breeding is to use genetic mapping to identify QTLs for key phenotypic variation followed by introgressing those QTLs into the elite gene pool with marker-assisted selection (MAS), which can enhance the selection criteria of phenotypes comparing to conventional breeding with the selection of genes. As the cost of genotyping continues to decline, the use of genotyping-by-sequencing (GBS) technologies or whole genome re-sequencing, coupled with the release of the genome sequences of plant species have permitted the development of dense arrays of single nucleotide polymorphisms (SNPs) covering the entire genome, which have in turn paved the way to genome-wide association studies (GWAS). Meanwhile, fine mapping guided by genome sequences of many plant species have facilitated the exploration of functional genes; in addition, pan-genomes constructed from various available resources such as the reference sequence and its variants, raw reads and haplotype reference panels provide a new perspective on QTL locations and potential molecular targets for plant breeding. Similarly, new approaches to marker-trait association analyses such as quantitative trait locus sequencing (QTL-seq) and quantitative trait gene sequencing (QTG-seq) that are based on bulked-segregant analysis (BSA) and whole-genome resequencing will help accelerate QTL fine-mapping and identification of the causal genes. In conclusion, the tools and strategies for MAS in modern plant breeding have been expanding in recent years. By embracing a broad array of conventional and new molecular techniques, modern plant breeding has a bright future in delivering new crop cultivars to keep our food, fiber and biobased economy diverse and safe.
