How to Code a Human


Book Description

An award-winning author takes us on a mind-bending journey through the world of DNA, exploring how it encodes our genes and make us unique. What is a genetic superhero? Is all DNA important? Can genetics affect your love life, mental health, and even ability to grow a tail? How to Code a Human answers these and many other questions as it investigates all aspects of modern genetics, from the evolution of our species to inherited disease, from "junk" DNA to the molecular processes inside our cells. This fascinating guide examines what gene sequencing reveals about who we are, how we're wired, and how we repair ourselves. Featuring stunning illustrations and infographics, this insightful guide to the code of life takes us on a beautiful visual journey--and is an essential read for anyone captivated by the scope of human discovery.




Regenesis


Book Description

A Harvard biologist and master inventor explores how new biotechnologies will enable us to bring species back from the dead, unlock vast supplies of renewable energy, and extend human life. In Regenesis, George Church and science writer Ed Regis explore the possibilities of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. These technologies-far from the out-of-control nightmare depicted in science fiction-have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span. A breathtaking look at the potential of this world-changing technology, Regenesis is nothing less than a guide to the future of life.




A Clinician's Guide to Sperm DNA and Chromatin Damage


Book Description

This comprehensive, up-to-date text, which brings together the key practical elements of the rapidly evolving field of sperm DNA and chromatin abnormalities, is divided thematically into five main sections. Part I discusses human sperm chromatin structure and nuclear architecture, while part II presents laboratory evaluation of sperm DNA damage, including SCSA, SCD, TUNEL and Comet assays, and cytochemical tests. Biological and clinical factors in the etiology of sperm DNA damage are discussed in part III, including oxidative stress, abortive apoptosis, cancer, and environmental and lifestyle factors. Part IV presents clinical studies on the utility of sperm DNA damage tests, both with natural and ART-assisted pregnancies, and debates the clinical utility of such tests. Finally, part V discusses current treatment options, such as antioxidant therapy, varicocelectomy, advanced sperm processing techniques and the use of testicular sperm. We are now beginning to better understand the unique organization of the sperm chromatin, as well as the nature and etiology of sperm DNA damage. Written and edited by worldwide experts in andrology, A Clinician's Guide to Sperm DNA and Chromatin Damage is an excellent resource for reproductive medicine and REI specialists, urologists, reproductive biologists and any professional working with the infertile male.







Herding Hemingway's Cats


Book Description

The language of genes has become common parlance. We know they make your eyes blue, your hair curly or your nose straight. The media tells us that our genes control the risk of cancer, heart disease, alcoholism or Alzheimer's. The cost of DNA sequencing has plummeted from billions of pounds to a few hundred, and gene-based advances in medicine hold huge promise. So we've all heard of genes, but how do they actually work? There are 2.2 metres of DNA inside every one of your cells, encoding roughly 20,000 genes. These are the 'recipes' that tell our cells how to make the building blocks of life, along with myriad control switches ensuring they're turned on and off at the right time and in the right place. But rather than a static string of genetic code, this is a dynamic, writhing biological library. Figuring out how it all works – how your genes build your body – is a major challenge for researchers around the world. And what they're discovering is that far from genes being a fixed, deterministic blueprint, things are much more random and wobbly than anyone expected. Drawing on stories ranging from six toed cats and stickleback hips to Mickey Mouse mice and zombie genes – told by researchers working at the cutting edge of genetics – Kat Arney explores the mysteries in our genomes with clarity, flair and wit, creating a companion reader to the book of life itself.




DNA (the Compact Guide)


Book Description

The Compact Guide: DNA is an engaging and essential read for anyone captivated by the scope of human discovery, and reveals how we might just uncover the answers to the secrets of life on Earth.




Ancient DNA Typing


Book Description

This is the definitive source of information on techniques for the identification and sequencing of old DNA (pieces) and their use in biological and medical research and application. Application of aDNA techniques are useful tools for investigations reaching from evolutionary studies to law enforcement approaches. What brings them together is the interest in specific methods of handling aDNA, i.e. elaborated PCR and sequencing techniques and the interpretation of the results. This books serves as an ideal guideline for it demonstrates how problem-solving strategies can be applied in various areas.




Rebel Cell


Book Description

Why do we get cancer? Is it our modern diets and unhealthy habits? Chemicals in the environment? An unwelcome genetic inheritance? Or is it just bad luck? The answer is all of these and none of them. We get cancer because we can't avoid it—it's a bug in the system of life itself. Cancer exists in nearly every animal and has afflicted humans as long as our species has walked the earth. In Rebel Cell: Cancer, Evolution, and the New Science of Life's Oldest Betrayal, Kat Arney reveals the secrets of our most formidable medical enemy, most notably the fact that it isn't so much a foreign invader as a double agent: cancer is hardwired into the fundamental processes of life. New evidence shows that this disease is the result of the same evolutionary changes that allowed us to thrive. Evolution helped us outsmart our environment, and it helps cancer outsmart its environment as well—alas, that environment is us. Explaining why "everything we know about cancer is wrong," Arney, a geneticist and award-winning science writer, guides readers with her trademark wit and clarity through the latest research into the cellular mavericks that rebel against the rigid biological "society" of the body and make a leap towards anarchy. We need to be a lot smarter to defeat such a wily foe—smarter even than Darwin himself. In this new world, where we know that every cancer is unique and can evolve its way out of trouble, the old models of treatment have reached their limits. But we are starting to decipher cancer's secret evolutionary playbook, mapping the landscapes in which these rogue cells survive, thrive, or die, and using this knowledge to predict and confound cancer's next move. Rebel Cell is a story about life and death, hope and hubris, nature and nurture. It's about a new way of thinking about what this disease really is and the role it plays in human life. Above all, it's a story about where cancer came from, where it's going, and how we can stop it.




Microbial Physiology Genetics and Ecology


Book Description

Microbial Physiology retains the logical, easy-to-follow organization of the previous editions. An introduction to cell structure and synthesis of cell components is provided, followed by detailed discussions of genetics, metabolism, growth, and regulation for anyone wishing to understand the mechanisms underlying cell survival and growth. This comprehensive reference approaches the subject from a modern molecular genetic perspective, incorporating new insights gained from various genome projects. The major objective of this book is to identify and focus attention on those methods and concepts that contribute to an understanding of organismal or genetic persistence. In addition, information about microbial physiology, genetics and ecology contributing to persistence of microorganisms or the measurement of persistence will be discussed. Consequently, there is a great need for more baseline information concerning the ecology of microbes in the natural environment. In determining the underlying risks associated with the release of genetically engineered microorganisms, both the target of risk and the critical exposure level must be identified.




Bang to Eternity and Betwixt


Book Description

Covering the Cosmos from before the Big Bang through to the creation of our universe and up to but not including our arrival on stage; our will is not yet imposed, we had no hand, act nor part in its provisions, beyond investigating to understand what has been delivered us. The many aspects of the Cosmos are melded, in a headline driven style, to paint a cohesive picture as well as allowing the reader choose to delve further where they may choose to paint their personal picture. Cosmos – includes; • The creation mechanism for our Universe and why there exists a possible Multiverse. • The creation mechanisms of the galaxies with their diversity of Star types. • The space exploration of our Solar System. • The Earth and Moon from their birth to their life driving engines for our planet. • The evolutionary processes that led to our arrival on the planet. • Our natural world with its great events. • Documentary video links on all topics of the book are included. The story is factual in manner, in the proper tradition of reporting, no personal opinions are expressed. The life stories of the standout personalities, in text and video, without whom what is now known, could not have been unraveled, in the case of Cosmos, they are; • Galileo Galilei • Isaac Newton • Albert Einstein • Charles Darwin This is a Video Book, vBook, beyond its text there are 150+ video titles, 100+ viewing hours, downloaded and stored locally on your computer, to be able to watch anytime, offline, without the need for local internet connection. Google ‘Cosmos’ and you get about 27,800,000 search results, so over these last several years I’ve searched out the best documentary videos with their hyperlinks included here, blending their content to report cohesively, supplementing, where appropriate, from Wikipedia and also include those hyperlinks for readers wanting to delve further. The ‘List of Contents’ runs to 6 levels to provide a form of map to the reader as the reporting sequence is not a mere chronology of Cosmic events, it delves, as necessary into the stories as to how the events became understood to us. There is a 7th level, hyperlinked, at its base, which brings further background content, from Wikipedia, to those who choose to read further into any of the topics. The ‘Index’ allows navigation for the reader who has specific interests to investigate through the fabric of the report. The ‘Text’ is structured to 4 levels beginning with the primary, headline driven, main body content followed by relevant Wikipedia extracts, indented in purple, for those choosing to read further into a particular topic through to hyperlinked Wikipedia - Full Article text within the book and in turn out to the website itself. For the reader that wants to stay with the big picture, main body content, there is a “Skip” link to take you past each of the extracts, on to the next headline title and main body content. There are 150+ video content links delivering 100+ hours of viewing time, of the best documentary film available online. The main sequence structure is; • Cosmology – Universe & Multiverse • Geology – Earth & Moon • Biology – Life – Plant & Animal • Ecology – Evolution & Environment – Plant, Animal & Human Special Edition There is also a Special Edition of this book available for US$49.95 which streams all video content from a secure Cloud Drive; therefore, video content cannot be removed by third party video platform providers such as YouTube, DailyMotion, Vimeo….. This Standard Edition streams from these. The Cloud Drive Server also allows you conveniently download to your local drive, as much video content as you choose, to watch, offline, at a time that best suits you. To view or purchase, paste the books ASIN: B00LEWY5WW into the Kindle Store search box. If you've any queries, feel welcome to contact [email protected]