Dopaminergic Alterations in Schizophrenia
Author : Silvia Gatti McArthur
Publisher : Frontiers Media SA
Page : 173 pages
File Size : 16,18 MB
Release : 2021-05-03
Category : Science
ISBN : 2889667316
Schizophrenia and Psychotic Spectrum Disorders
Author : S. Charles Schulz
Publisher : Oxford University Press
Page : 401 pages
File Size : 26,11 MB
Release : 2016-04-01
Category : Medical
ISBN : 019937807X
Book Description
Schizophrenia and Psychotic Spectrum Disorders aims to engage young caregivers in psychiatry, psychology, nursing and social work so that they will be able to become well informed about this significant--and at times confusing--illness. Because schizophrenia is considered to be one of the most complicated and severe psychiatric disorders, this book has the goal of summarizing key issues of the illness, such as its presentation, frequency and age of onset, and diagnostic characteristics. It also contains informative chapters about the pathophysiology of schizophrenia, ranging from brain development issues, genetics, and likely abnormalities in neurotransmitters. This book will give young professionals and those joining the field an excellent and accessible background to treatment. In this area, Schizophrenia and Psychotic Spectrum Disorders provides a comprehensive approach to diagnosis, treatment initiation, strategies for non-response, approaches of therapy, and importantly, ways to provide family therapy and support.
Psychotic Disorders
Author : Carol A. Tamminga MD
Publisher : Oxford University Press
Page : 400 pages
File Size : 33,37 MB
Release : 2020-10-20
Category : Medical
ISBN : 0190653299
Book Description
Psychotic Disorders: Comprehensive Conceptualization and Treatments emphasizes a dimensional approach to psychosis--one of the most fascinating manifestations of altered brain behavior--that cuts across a broad array of psychiatric diagnoses from schizophrenia to affective psychosis and organic disorders like epilepsy and dementias. Written by an international roster of over seventy leading experts in the field, this volume comprehensively reviews, critiques, and integrates available knowledge on the etiology, mechanisms, and treatments of psychotic disorders, and outlines ways forward in both research and clinical practice towards more objective, mechanistically-based definitions of psychotic disorders. Chapters address topics such as psychosis phenomenology, biomarkers and treatments, the overlaps and interfaces between psychiatric disorders within the psychosis dimension, and novel disease definitions. Furthermore, the volume incorporates findings on potential mechanisms, bridges between various system levels (i.e., genetic, epigenetic, molecular and cellular, brain circuit and function, psychological, social, environmental and cultural) and their interactions, as well as the potential role in causation and/or mediation in psychotic disorders. Finally, the volume outlines a broad array of treatment approaches, from the readily available (e.g., psychopharmacology, various modalities of psychotherapy) to the experimental (e.g., cognitive interventions, neuromodulation). With a concluding section of forward perspectives conjecturing future directions and related challenges, this book aspires to stimulate new knowledge, generate novel frameworks, and carry new directions forward on psychotic disorders.
Neurobiology of Brain Disorders
Author : Michael J. Zigmond
Publisher : Elsevier
Page : 823 pages
File Size : 32,7 MB
Release : 2014-12-03
Category : Science
ISBN : 0123982804
Book Description
Neurobiology of Brain Disorders is the first book directed primarily at basic scientists to offer a comprehensive overview of neurological and neuropsychiatric disease. This book links basic, translational, and clinical research, covering the genetic, developmental, molecular, and cellular mechanisms underlying all major categories of brain disorders. It offers students, postdoctoral fellows, and researchers in the diverse fields of neuroscience, neurobiology, neurology, and psychiatry the tools they need to obtain a basic background in the major neurological and psychiatric diseases, and to discern connections between basic research and these relevant clinical conditions. This book addresses developmental, autoimmune, central, and peripheral neurodegeneration; infectious diseases; and diseases of higher function. The final chapters deal with broader issues, including some of the ethical concerns raised by neuroscience and a discussion of health disparities. Included in each chapter is coverage of the clinical condition, diagnosis, treatment, underlying mechanisms, relevant basic and translational research, and key unanswered questions. Written and edited by a diverse team of international experts, Neurobiology of Brain Disorders is essential reading for anyone wishing to explore the basic science underlying neurological and neuropsychiatric diseases. - Links basic, translational, and clinical research on disorders of the nervous system, creating a format for study that will accelerate disease prevention and treatment - Covers a vast array of neurological disorders, including ADHD, Down syndrome, autism, muscular dystrophy, diabetes, TBI, Parkinson, Huntington, Alzheimer, OCD, PTSD, schizophrenia, depression, and pain - Illustrated in full color - Each chapter provides in-text summary points, special feature boxes, and research questions - Provides an up-to-date synthesis of primary source material
Schizophrenia
Author : Steven M. Silverstein
Publisher : MIT Press
Page : 403 pages
File Size : 42,83 MB
Release : 2013-11-15
Category : Medical
ISBN : 0262019620
Book Description
Leading researchers address conceptual and technical issues in schizophrenia and suggest novel strategies for advancing research and treatment. Despite major advances in methodology and thousands of published studies every year, treatment outcomes in schizophrenia have not improved over the last fifty years. Moreover, we still lack strategies for prevention and we do not yet understand how the interaction of genetic, developmental, and environmental factors contribute to the disorder. In this book, leading researchers consider conceptual and technical obstacles to progress in understanding schizophrenia and suggest novel strategies for advancing research and treatment. The contributors address a wide range of critical issues: the construct of schizophrenia itself; etiology, risk, prediction, and prevention; different methods of modeling the disorder; and treatment development and delivery. They identify crucial gaps in our knowledge and offer creative but feasible suggestions. These strategies include viewing schizophrenia as a heterogeneous group of conditions; adopting specific new approaches to prediction and early intervention; developing better integration of data across genetics, imaging, perception, cognition, phenomenology, and other fields; and moving toward an evidence-based, personalized approach to treatment requiring rational clinical decision-making to reduce functional disability. Contributors Robert Bittner, Robert W. Buchanan, Kristin S. Cadenhead, William T. Carpenter, Jr., Aiden Corvin, Daniel Durstewitz, André A. Fenton, Camilo de la Fuente-Sandoval, Jay A. Gingrich, Joshua A. Gordon, Chloe Gott, Peter B. Jones, René S. Kahn, Richard Keefe, Wolfgang Kelsch, James L. Kennedy, Matcheri S. Keshavan, Angus W. MacDonald III, Anil K. Malhotra, John McGrath, Andreas Meyer-Lindenberg, Kevin J. Mitchell, Bita Moghaddam, Vera A. Morgan, Craig Morgan, Kim T. Mueser, Karoly Nikolich, Patricio O'Donnell, Michael O'Donovan, William A. Phillips, Wulf Rössler, Louis Sass, Akira Sawa, Jeremy K. Seamans, Steven M. Silverstein, William Spaulding, Sharmili Sritharan, Heike Tost, Peter Uhlhaas, Aristotle Voineskos, Michèle Wessa, Leanne M. Williams, Ashley Wilson, Til Wykes
The Neuropathology of Schizophrenia
Author : Paul J. Harrison
Publisher :
Page : 402 pages
File Size : 34,81 MB
Release : 2000-08-24
Category : Medical
ISBN :
Book Description
What is schizophrenia? This is one of the most controversial questions in psychiatry and mental health research; however, in the last twenty years, there have been significant advances in our understanding of the topic. This book provides a balanced, comprehensive and up-to-date overview of the neuropathology of schizophrenia and its interpretation, covering the latest evidence derived from all fields of research, from brain scans to microscopy. The authors include many of the foremost international authorities in this rapidly developing field.
From Neuron to Action
Author : Lüder Deecke
Publisher : Springer Science & Business Media
Page : 656 pages
File Size : 20,68 MB
Release : 2013-03-09
Category : Medical
ISBN : 3662026015
Book Description
A rich source of information about human voluntary movement in health and disease can be found in this book. The most esteemed researchers in their respective fields bring you up-to-date articles. Their collected work combines fundamental research in the life sciences with clinical neuroscience in a unique overview. The interdisciplinary aspects of motor physiology uncover a wealth of information for researchers from neighboring disciplines. For example, oculomotor research, vestibular research, equilibrium, sensory research and cognition, evolution, synaptic and elementary processes and the neurological sciences can be discovered.
Schizo-Obsessive Disorder
Author : Michael Poyurovsky
Publisher : Cambridge University Press
Page : 249 pages
File Size : 13,36 MB
Release : 2013-01-17
Category : Medical
ISBN : 1107000122
Book Description
This is the first book to address the clinical and neurobiological interface between schizophrenia and obsessive-compulsive disorder (OCD). There is growing evidence that obsessive-compulsive symptoms in schizophrenia are prevalent, persistent and characterized by a distinct pattern of familial inheritance, neurocognitive deficits and brain activation. This text provides guidelines for differential diagnosis of schizophrenic patients with obsessive-compulsive symptoms, and patients with primary OCD alongside poor insight, psychotic features or schizotypal personality. Written by a leading expert in the coexistence of obsessive-compulsive and schizophrenic phenomena, Schizo-Obsessive Disorder uses numerous case studies to present diagnostic guidelines and to describe a recommended treatment algorithm, demystifying this complex disorder and aiding its effective management. The book is essential reading for psychiatrists, neurologists and the wider range of multidisciplinary mental health practitioners.
The Neurobiology of Schizophrenia
Author : Ted Abel
Publisher : Academic Press
Page : 470 pages
File Size : 40,46 MB
Release : 2016-07-08
Category : Psychology
ISBN : 0128018771
Book Description
The Neurobiology of Schizophrenia begins with an overview of the various facets and levels of schizophrenia pathophysiology, ranging systematically from its genetic basis over changes in neurochemistry and electrophysiology to a systemic neural circuits level. When possible, the editors point out connections between the various systems. The editors also depict methods and research strategies used in the respective field. The individual backgrounds of the two editors promote a synthesis between basic neuroscience and clinical relevance. - Provides a comprehensive overview of neurobiological aspects of schizophrenia - Discusses schizophrenia at behavioral, cognitive, clinical, electrophysiological, molecular, and genetic levels - Edited by a translational researcher and a psychiatrist to promote synthesis between basic neuroscience and clinical relevance - Elucidates connections between the various systems depicted, when possible
Applied Regression Including Computing and Graphics
Author : R. Dennis Cook
Publisher : John Wiley & Sons
Page : 632 pages
File Size : 45,54 MB
Release : 2009-09-25
Category : Mathematics
ISBN : 0470317787
Book Description
A step-by-step guide to computing and graphics in regression analysis In this unique book, leading statisticians Dennis Cook and Sanford Weisberg expertly blend regression fundamentals and cutting-edge graphical techniques. They combine and up- date most of the material from their widely used earlier work, An Introduction to Regression Graphics, and Weisberg's Applied Linear Regression; incorporate the latest in statistical graphics, computing, and regression models; and wind up with a modern, fully integrated approach to one of the most important tools of data analysis. In 23 concise, easy-to-digest chapters, the authors present:? A wealth of simple 2D and 3D graphical techniques, helping visualize results through graphs * An improved version of the user-friendly Arc software, which lets readers promptly implement new ideas * Complete coverage of regression models, including logistic regression and generalized linear models * More than 300 figures, easily reproducible on the computer * Numerous examples and problems based on real data * A companion Web site featuring free software and advice, available at www.wiley.com/mathem atics Accessible, self-contained, and fully referenced, Applied Regression Including Computing and Graphics assumes only a first course in basic statistical methods and provides a bona fide user manual for the Arc software. It is an invaluable resource for anyone interested in learning how to analyze regression problems with confidence and depth.
