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Drugs in Neurology

Author : Sathiji Nageshwaran

Publisher : Oxford University Press

Page : 552 pages

File Size : 25,51 MB

Release : 2017-01-26

Category : Medical

ISBN : 0191641243

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Book Description

Part of the Drugs in series, this book provides an easily accessible pocket-sized guide to the use of medications when treating patients with neurological ailments. Drugs in Neurology covers the breadth of medications used in modern neurology, including each drug's indications, contra-indications, side-effects and important interactions. The underlying pharmacology also feature (where known). Practical aspects related to prescribing and therapeutic drug monitoring are covered and based on the most up-to-date evidence-based guidance. Each drug monograph contains a small section drawing on the wisdom of the senior contributors of each chapter with regards to using the medication.



Drug-induced Neurological Disorders

Author : Kewal K. Jain

Publisher : Seattle : Hogrefe & Huber Publishers

Page : 406 pages

File Size : 40,94 MB

Release : 1996

Category : Medical

ISBN :

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Book Description

Emphasizing the relevance of recent findings to the differential diagnoses of a wide range of neurological conditions, this book offers an account of drug- induced neurological disorders. Specific chapters discuss epidemiology and clinical significance, pathomechanisms, encephalopathies, disorders of consciousness, neuropsychiatric disorders, headaches, seizures, movement disorders, cerebrovascular disorders, myopathies, diseases of the spine and spinal cord, cerebellar disorders, aseptic meningitis, benign intracranial hypertension, disorders of the automatic nervous system, sleep disorders, Eosinophilia Myalgia Syndrome, serotonin syndrome, Gillian-Barre syndrome, subacute myelo-optico-neuropathy, and pituitary disorders. Jain is a consultant in pharmaceutical medicine. Annotation copyrighted by Book News Inc., Portland, OR.



Principles of Drug Therapy in Neurology

Author : Michael V. Johnston

Publisher : Oxford University Press, USA

Page : 394 pages

File Size : 39,12 MB

Release : 1992

Category : Medical

ISBN :

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Book Description

Once considered largely untreatable, neurologic disorders have become the newest frontier for breakthrough research in pharmacology. Principles of Drug Therapy in Neurology discusses the latest investigatinal strategies and theories and how they affect current clinical practice. The book details the mechanisms, delivery systems, and efficacy of the latest medication, as the editors outline a "method" for thinking about the action of clinically useful drugs, based on modern information about kinetics, transport to the brain, interaction with neurotransmitter systems and membrane action, etc. All types of major neurologic disorders are discussed.



The Hospital Neurology Book

Author : Arash Salardini

Publisher : McGraw Hill Professional

Page : 982 pages

File Size : 42,80 MB

Release : 2016-04-22

Category : Medical

ISBN : 0071845828

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Book Description

A practical, protocol-oriented guide to the practice of neurology in the hospital setting A Doody's Core Title for 2019! Hospital neurology is one of the fastest growing subspecialties within neurology. Running an efficient and effective neurohospitalist line is important to the financial success of hospitals and the physicians employed there. Many neurology patients also have internal medicine problems, and often it is a general hospitalist without neurology training who treat these patients. These physicians sorely need more information on neurology. Conversely, neurologists caring for these patients have only had one year of internal medicine training and require more guidance on medical problems. Given these realities, there is a need for a resource on hospital neurology. With The Hospital Neurology Book, Drs. Salardini and Biller have created a practical, concise, and useful work that guides both neurologists and internists in the areas in which their training is currently not sufficient for hospital practice. The Hospital Neurology Book features a highly readable format, providing information physicians can act upon, including recipes and protocols for patient care and question-based chapter headings that lead physicians to the exact issue they are dealing with in the moment. Each chapter (or chapter section as appropriate) opens with a case study, setting the stage in a highly practical manner, and ends with high yield summary points useful for consolidating learning.



Disease Control Priorities, Third Edition (Volume 4)

Author : Vikram Patel

Publisher : World Bank Publications

Page : 307 pages

File Size : 28,21 MB

Release : 2016-03-10

Category : Medical

ISBN : 1464804281

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Book Description

Mental, neurological, and substance use disorders are common, highly disabling, and associated with significant premature mortality. The impact of these disorders on the social and economic well-being of individuals, families, and societies is large, growing, and underestimated. Despite this burden, these disorders have been systematically neglected, particularly in low- and middle-income countries, with pitifully small contributions to scaling up cost-effective prevention and treatment strategies. Systematically compiling the substantial existing knowledge to address this inequity is the central goal of this volume. This evidence-base can help policy makers in resource-constrained settings as they prioritize programs and interventions to address these disorders.



Addictive Substances and Neurological Disease

Author : Ronald Ross Watson

Publisher : Academic Press

Page : 416 pages

File Size : 49,50 MB

Release : 2017-02-18

Category : Medical

ISBN : 0128092963

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Book Description

Addictive Substances and Neurological Disease: Alcohol, Tobacco, Caffeine, and Drugs of Abuse in Everyday Lifestyles is a complete guide to the manifold effects of addictive substances on the brain, providing readers with the latest developing research on how these substances are implicated in neurological development and dysfunction. Cannabis, cocaine, and other illicit drugs can have substantial negative effects on the structure and functioning of the brain. However, other common habituating and addictive substances often used as part of an individual's lifestyle, i.e., alcohol, tobacco, caffeine, painkillers can also compromise brain health and effect or accentuate neurological disease. This book provides broad coverage of the effects of addictive substances on the brain, beginning with an overview of how the substances lead to dysfunction before examining each substance in depth. It discusses the pathology of addiction, the structural damage resulting from abuse of various substances, and covers the neurobiological, neurodegenerative, behavioral, and cognitive implications of use across the lifespan, from prenatal exposure, to adolescence and old age. This book aids researchers seeking an understanding of the neurological changes that these substances induce, and is also extremely useful for those seeking potential treatments and therapies for individuals suffering from chronic abuse of these substances. - Integrates current research on the actions of addictive substances in neurological disease - Includes functional foods, such as caffeine beverages, that have habituating effects on the brain - Provides a synopsis of key ideas associated with the consequences of addictive and habituating lifestyle substances



The Interface of Neurology & Internal Medicine

Author : José Biller

Publisher : Lippincott Williams & Wilkins

Page : 1086 pages

File Size : 50,1 MB

Release : 2008

Category : Medical

ISBN : 9780781779067

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Book Description

This book is the first comprehensive reference on the interface between neurology and internal medicine. In 171 chapters organized by organ system, the book examines the neurologic manifestations of dozens of medical conditions, the neurologic effects of drugs, organ transplantation, and other treatments, and the medical comorbidities or complications—iatrogenic or otherwise—that neurologists must diagnose and treat in patients with neurologic disease. Most chapters are co-authored by a neurologist and a non-neurologic specialist. Each chapter presents information in an accessible format and includes a case vignette and the authors' recommendations for the case. A companion Website provides a multiple-choice question for each chapter and the fully searchable text, with case vignettes and recommendations linked.



Behavioral Neuroscience of Drug Addiction

Author : David W. Self

Publisher : Springer Science & Business Media

Page : 392 pages

File Size : 37,25 MB

Release : 2009-12-18

Category : Medical

ISBN : 3642030017

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Book Description

Drug addiction is a chronically relapsing mental illness involving severe motivational disturbances and loss of behavioral control leading to personal dev- tation. The disorder af?icts millions of people, often co-occurring with other mental illnesses with enormous social and economic costs to society. Several decades of research have established that drugs of abuse hijack the brain’s natural reward substrates, and that chronic drug use causes aberrant alterations in these rewa- processing systems. Such aberrations may be demonstrated at the cellular, neu- transmitter, and regional levels of information processing using either animal models or neuroimaging in humans following chronic drug exposure. Behaviorally, these neural aberrations manifest as exaggerated, altered or dysfunctional expr- sion of learned behavioral responses related to the pursuit of drug rewards, or to environmental factors that precipitate craving and relapse during periods of drug withdrawal. Current research efforts are aimed at understanding the associative and causal relationships between these neurobiological and behavioral events, such that treatment options will ultimately employ therapeutic amelioration of neural de?cits and restoration of normal brain processing to promote efforts to abstain from further drug use. The Behavioral Neuroscience of Drug Addiction, part of the Springer series on Current Topics in Behavioral Neurosciences, contains scholarly reviews by noted experts on multiple topics from both basic and clinical neuroscience ?elds.



Drugs, Addiction, and the Brain

Author : George F. Koob

Publisher : Academic Press

Page : 351 pages

File Size : 44,85 MB

Release : 2014-07-12

Category : Medical

ISBN : 0123869595

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Book Description

Drugs, Addiction, and the Brain explores the molecular, cellular, and neurocircuitry systems in the brain that are responsible for drug addiction. Common neurobiological elements are emphasized that provide novel insights into how the brain mediates the acute rewarding effects of drugs of abuse and how it changes during the transition from initial drug use to compulsive drug use and addiction. The book provides a detailed overview of the pathophysiology of the disease. The information provided will be useful for neuroscientists in the field of addiction, drug abuse treatment providers, and undergraduate and postgraduate students who are interested in learning the diverse effects of drugs of abuse on the brain. - Full-color circuitry diagrams of brain regions implicated in each stage of the addiction cycle - Actual data figures from original sources illustrating key concepts and findings - Introduction to basic neuropharmacology terms and concepts - Introduction to numerous animal models used to study diverse aspects of drug use. - Thorough review of extant work on the neurobiology of addiction



Improving and Accelerating Therapeutic Development for Nervous System Disorders

Author : Institute of Medicine

Publisher : National Academies Press

Page : 107 pages

File Size : 45,13 MB

Release : 2014-02-06

Category : Medical

ISBN : 0309292492

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Book Description

Improving and Accelerating Therapeutic Development for Nervous System Disorders is the summary of a workshop convened by the IOM Forum on Neuroscience and Nervous System Disorders to examine opportunities to accelerate early phases of drug development for nervous system drug discovery. Workshop participants discussed challenges in neuroscience research for enabling faster entry of potential treatments into first-in-human trials, explored how new and emerging tools and technologies may improve the efficiency of research, and considered mechanisms to facilitate a more effective and efficient development pipeline. There are several challenges to the current drug development pipeline for nervous system disorders. The fundamental etiology and pathophysiology of many nervous system disorders are unknown and the brain is inaccessible to study, making it difficult to develop accurate models. Patient heterogeneity is high, disease pathology can occur years to decades before becoming clinically apparent, and diagnostic and treatment biomarkers are lacking. In addition, the lack of validated targets, limitations related to the predictive validity of animal models - the extent to which the model predicts clinical efficacy - and regulatory barriers can also impede translation and drug development for nervous system disorders. Improving and Accelerating Therapeutic Development for Nervous System Disorders identifies avenues for moving directly from cellular models to human trials, minimizing the need for animal models to test efficacy, and discusses the potential benefits and risks of such an approach. This report is a timely discussion of opportunities to improve early drug development with a focus toward preclinical trials.