Dynamic Light Scattering Spectroscopy of the Human Eye


Book Description

Blindness or serious vision impairment is one of the most feared disabilities known to humankind. A 2016 report compiled by the National Eye Institute (NEI) of the National Institutes of Health (NIH) and Prevent Blindness America states that although half of all blindness can be prevented, the number of people who suffer vision loss continues to increase. The technique of dynamic light scattering (DLS) was developed by physicists in the late 1960s to early 1970s. DLS is now emerging as a potential ophthalmic tool, making possible studies of virtually every tissue and fluid comprising the eye, thus pushing the envelope for broader applications in ophthalmology. This book presents a comprehensive review of the application of light scattering in clinical use. It is the first of its kind, offering insight to how DLS can be applied to the human eye as well as animals. Chapters discuss DLS in neurological diseases, including protocols, informed consent, and patents. Dynamic Light Scattering Spectroscopy of the Human Eye is a must-have resource for physicians, engineers, and physicists interested in the clinical application of DLS to diagnose and potentially treat medical conditions in a non-invasive, quantitative and novel way.




Mesoscopic Thermodynamics for Scientists and Engineers


Book Description

Provides comprehensive coverage of the fundamentals of mesoscopic thermodynamics Mesoscopic Thermodynamics for Scientists and Engineers presents a unified conceptual approach to the core principles of equilibrium and nonequilibrium thermodynamics. Emphasizing the concept of universality at the mesoscale, this authoritative textbook provides the knowledge required for understanding and utilizing mesoscopic phenomena in a wide range of new and emerging technologies. Divided into two parts, Mesoscopic Thermodynamics for Scientists and Engineers opens with a concise summary of classical thermodynamics and nonequilibrium thermodynamics, followed by a detailed description of fluctuations and local (spatially-dependent) properties. Part II presents a universal approach to specific meso-heterogeneous systems, illustrated by numerous examples from experimental and computational studies that align with contemporary research and engineering practice. Bridges the gap between conventional courses in thermodynamics and real-world practice Provides in-depth instruction on applying thermodynamics to current problems involving meso- and nano-heterogeneous systems Contains a wealth of examples of simple and complex fluids, polymers, liquid crystals, and supramolecular equilibrium and dissipative structures Includes practical exercises and references to textbooks, monographs, and journal articles in each chapter Mesoscopic Thermodynamics for Scientists and Engineers is an excellent textbook for advanced undergraduate and graduate students in physics, chemistry, and chemical, mechanical, and materials science engineering, as well as an invaluable reference for engineers and researchers engaged in soft-condensed matter physics and chemistry, nanoscience and nanotechnology, and mechanical, chemical, and biomolecular engineering.




Light Scattering and Photon Correlation Spectroscopy


Book Description

Since their inception more than 2.5 years ago, photon correlation techniques for the spatial, temporal or spectral analysis of fluctuating light fields have found an ever-widening range of applications. Using detectors which re spond to single quanta of the radiation field, these methods are intrinsically digital in natnre and in many experimental situations offer a unique degree of accuracy and sensitivity, not only for the study of primary light sources themselves, but most particularly in the use of a laser-beam probe to study light scattering from pure fluids, macromolecular suspensions and laminar or turbulent flowing fluids and gases. Following the earliest developments in laser scattering by dilute macro nl01ecular suspensions, in , ... hich particle sizing was the main aim, and the use of photon correlation techniques for laser-Doppler studies of flow and tnrbuence. both of which areas were the subject of NATO ASls in Capri, Italy in 19;:3 and 19;6. significant advances have be('n made in recent years in many other areas. These were reflected in the topics covered in this NATO Advanced Research Workshop, which took place from August 2;th to 30th, 1!)!}6, at the Jagiellonian University, Krakow, Poland. These in cluded ('xperimental techniques. statist.ics and data reduction, colloids and aggregation, polymers, gels, liquid crystals and mixtures, protein solutions, critical pllf'nomena and dense media.




Femtosecond Laser: Techniques and Technology


Book Description

The book Femtosecond Laser: Techniques and Technology provides complete insight of Femtosecond Laser technology in various ocular indications. Refractive Surgery technology has undergone rapid advancements and innovations in last two decades. Femtosecond Laser offers new possibilities in the field of minimally invasive corneal surgery. It employs near infrared pulses to cut tissue with minimal collateral tissue damage. The highly localized tissue effect of low energy Femtosecond Laser shall expand the capabilities and precision of this technology in near future and may be used to create three-dimensional intrastromal resection with micron precision. Femtosecond laser is a simple, rapid reliable and efficient method in ophthalmology with satisfactory results for effective lens position and refractive outcome. Femtosecond laser is enjoying rapid growth in the area of cataract surgery. The Femtosecond Laser has proved its versatility in Lamellar keratoplasty, customized trephination in penetrating keratoplasty, tunnel creation for intracorneal ring segments, astigmatic keratotomy for keratoprostheses, non-invasive trans-scleral glaucoma surgery, retinal imaging presbyopic surgery and cataract surgery. Advances in ultrafast laser technology continued to improve the surgical safety, efficiency, speed and versatility of Femtosecond Lasers in Ophthalmology. Femtosecond Laser finds application in anterior and posterior segment indications of ophthalmology.




Handbook of Biophotonics


Book Description

This new handbook covers the world of biophotonics not only geographically -- with the editors coming from different continents -- but also in terms of content, since the authors come from the whole spectrum of biophotonic basic and applied research. Designed to set the standard for the scientific community, these three volumes break new ground by providing readers with the physics basics as well as the biological and medical background, together with detailed reports on recent technical advances. The Handbook also adopts an application-related approach, starting with the application and then citing the various tools to solve the scientific task, making it of particular value to medical doctors. Divided into several sections, the first part offers introductory chapters on the different fields of research, with subsequent parts focusing on the applications and techniques in various fields of industry and research. The result is a handy source for scientists seeking the basics in a condensed form, and equally a reference for quickly gathering the knowledge from neighboring disciplines. Absolutely invaluable for biophotonic scientists in their daily work.







Vital Dyes in Vitreoretinal Surgery


Book Description

Chromovitrectomy is a novel approach to visualize the vitreous or retinal surface during vitreoretinal surgery. In recent years, the widely used indocyanine green (ICG) has made the surgical maneuver of inner limiting membrane peeling tremendously safer and efficient. Also, numerous dyes have been applied in experimental settings with promising or devastating results. This volume highlights the major clinical and experimental results of currently used novel vital dyes. The first chapters describe the transparent structure of the vitreous body and summarize historical considerations to visualize its structure by optical coherence tomography, dye injections or autologous cells during surgery and for diagnostic purposes. The following contributions describe the advantages and disadvantages of ICG during vitreoretinal surgery and experimental applications. Alternative approaches by recently approved vital dyes such as trypan blue, patent blue and brilliant blue are evaluated in the subsequent chapters. Finally the last few chapters give an outlook on novel vital dyes, which are currently under evaluation, as well as alternative enzymatic approaches to remove the vitreous from the retinal surface. Being a timely update this publication will be indispensable reading for vitreoretinal surgeons and ophthalmic researchers.




Adler's Physiology of the Eye E-Book


Book Description

Written and designed to enhance your understanding of ocular function, structure, and anatomy, Adler's Physiology of the Eye is a classic, best-selling text that makes critical information easier to learn and retain. The fully revised 12th Edition continues the successful Adler's approach that connects basic science and clinical aspects in a user-friendly, highly visual format—ideal for study, review, and exam preparation. It captures the latest molecular, genetic, and biochemical discoveries and offers you unparalleled knowledge and insight into the physiology of the eye and its structures. - Covers the full structure and function of the eye and its related anatomy and makes the connection between physiology and clinical practice. - Includes major updates throughout, including new information on OCT/OCTA imaging, new drug delivery methods, ocular biomechanics, and evolving gene therapies. - Organizes content by function, rather than anatomy, to help you make a stronger connection between physiological principles and clinical practice. - Explains the physiological principles that underlie visual acuity, intraocular pressure, ocular circulation, the extraocular muscles, and much more. - Features approximately 1,000 illustrations throughout, including medical artwork; schematics, charts, and graphs; clinical photographs; and more. - Any additional digital ancillary content may publish up to 6 weeks following the publication date.




Dynamic Light Scattering


Book Description

In the twenty years since their inception, modern dynamic light-scattering techniques have become increasingly sophisticated, and their applications have grown exceedingly diverse. Applications of the techniques to problems in physics, chemistry, biology, medicine, and fluid mechanics have prolifer ated. It is probably no longer possible for one or two authors to write a monograph to cover in depth the advances in scattering techniques and the main areas in which they have made a major impact. This volume, which we expect to be the first of aseries, presents reviews of selected specialized areas by renowned experts. It makes no attempt to be comprehensive; it emphasizes a body of related applications to polymeric, biological, and colloidal systems, and to critical phenomena. The well-known monographs on dynamic light scattering by Berne and Pecora and by Chu were published almost ten years ago. They provided comprehensive treatments of the general principles of dynamic light scat tering and gave introductions to a wide variety of applications, but natu rally they could not treat the new applications and advances in older ones that have arisen in the last decade. The new applications include studies of interacting particles in solution (Chapter 4); scaling approaches to the dynamics of polymers, including polymers in semidilute solution (Chapter 5); the use of both Fabry-Perot interferometry and photon correlation spectroscopy to study bulk polymers (Chapter 6); studies of micelIes and microemulsions (Chapter 8); studies of polymer gels (Chapter 9).




Sensors And Microsystems, Proceedings Of The 1st Italian Conference


Book Description

This book offers a unique view on the current sensors and microsystems research and development in Italy.Papers, from the most important academic and industrial research labs, cover many aspects of the fields of bio-chemical and physical sensors.Outstanding contributions regards advanced topics such as bio-sensors, new materials for chemical sensing, electronic nose, microsystems for medical applications and low-voltage electronics.The conference was organized by the Italian Association for Sensors and Microsystems (AISEM).