Dynamic Modelling of Diabetes Mellitus
Author : Wanda Rae Puckett
Publisher :
Page : 594 pages
File Size : 37,95 MB
Release : 1992
Category :
ISBN :
Author : Wanda Rae Puckett
Publisher :
Page : 594 pages
File Size : 37,95 MB
Release : 1992
Category :
ISBN :
Author : Eleni I. Georga
Publisher : Academic Press
Page : 253 pages
File Size : 10,43 MB
Release : 2017-12-11
Category : Computers
ISBN : 0128051469
Personalized Predictive Modeling in Diabetes features state-of-the-art methodologies and algorithmic approaches which have been applied to predictive modeling of glucose concentration, ranging from simple autoregressive models of the CGM time series to multivariate nonlinear regression techniques of machine learning. Developments in the field have been analyzed with respect to: (i) feature set (univariate or multivariate), (ii) regression technique (linear or non-linear), (iii) learning mechanism (batch or sequential), (iv) development and testing procedure and (v) scaling properties. In addition, simulation models of meal-derived glucose absorption and insulin dynamics and kinetics are covered, as an integral part of glucose predictive models. This book will help engineers and clinicians to: select a regression technique which can capture both linear and non-linear dynamics in glucose metabolism in diabetes, and which exhibits good generalization performance under stationary and non-stationary conditions; ensure the scalability of the optimization algorithm (learning mechanism) with respect to the size of the dataset, provided that multiple days of patient monitoring are needed to obtain a reliable predictive model; select a features set which efficiently represents both spatial and temporal dependencies between the input variables and the glucose concentration; select simulation models of subcutaneous insulin absorption and meal absorption; identify an appropriate validation procedure, and identify realistic performance measures. Describes fundamentals of modeling techniques as applied to glucose control Covers model selection process and model validation Offers computer code on a companion website to show implementation of models and algorithms Features the latest developments in the field of diabetes predictive modeling
Author : Vasilis Marmarelis
Publisher : Springer Science & Business
Page : 241 pages
File Size : 18,5 MB
Release : 2014-04-22
Category : Technology & Engineering
ISBN : 3642544649
This contributed volume presents computational models of diabetes that quantify the dynamic interrelationships among key physiological variables implicated in the underlying physiology under a variety of metabolic and behavioral conditions. These variables comprise for example blood glucose concentration and various hormones such as insulin, glucagon, epinephrine, norepinephrine as well as cortisol. The presented models provide a powerful diagnostic tool but may also enable treatment via long-term glucose regulation in diabetics through closed-look model-reference control using frequent insulin infusions, which are administered by implanted programmable micro-pumps. This research volume aims at presenting state-of-the-art research on this subject and demonstrating the potential applications of modeling to the diagnosis and treatment of diabetes. The target audience primarily comprises research and experts in the field but the book may also be beneficial for graduate students.
Author : Sean Ewings
Publisher :
Page : pages
File Size : 19,65 MB
Release : 2012
Category :
ISBN :
Author : Ahmad Uzair Mazlan
Publisher :
Page : 0 pages
File Size : 12,60 MB
Release : 2017
Category :
ISBN :
Author : Massoud Boroujerdi
Publisher : Independently Published
Page : 0 pages
File Size : 30,42 MB
Release : 2024-07-02
Category : Science
ISBN :
This book introduces a generic negative feedback mathematical model for describing the dynamics of substrates or hormones. The most attractive feature of this model is that it can describe time-varying blood/plasma concentration with changes in its clearance rate and/or production rate. This negative feedback model is more versatile than the conventional compartmental models because it can also produce oscillatory responses. The glucose and insulin dynamics in type one diabetes mellitus are used as examples. The models are implemented as a Shiny - app to enhance diabetic patients' education about underlying dynamics.
Author : James L. Hargrove
Publisher : Springer Science & Business Media
Page : 332 pages
File Size : 22,70 MB
Release : 1998-06-02
Category : Mathematics
ISBN : 9780387949963
This book and CD-ROM package integrates the use of STELLA software into the teaching of health, nutrition and physiology, and may be used on its own in nutrition and physiology courses, or can serve as a supplement to introduce the role that simulation modelling can play. The author presents key subjects ranging from the theory of metabolic control, through weight regulation to bone metabolism, and gives readers the tools to simulate these using the STELLA software. Topics include methods for simulation of gene expression, a multi-stage model of tumour development, theories of ageing, circadian rhythms and physiological time, as well as a model for managing weight loss and preventing obesity.
Author : Peter S. Hovmand
Publisher : Springer Science & Business Media
Page : 117 pages
File Size : 42,57 MB
Release : 2013-11-09
Category : Psychology
ISBN : 1461487633
Community Based System Dynamics introduces researchers and practitioners to the design and application of participatory systems modeling with diverse communities. The book bridges community- based participatory research methods and rigorous computational modeling approaches to understanding communities as complex systems. It emphasizes the importance of community involvement both to understand the underlying system and to aid in implementation. Comprehensive in its scope, the volume includes topics that span the entire process of participatory systems modeling, from the initial engagement and conceptualization of community issues to model building, analysis, and project evaluation. Community Based System Dynamics is a highly valuable resource for anyone interested in helping to advance social justice using system dynamics, community involvement, and group model building, and helping to make communities a better place.
Author : Troy M. Bremer
Publisher :
Page : 556 pages
File Size : 34,34 MB
Release : 1999
Category :
ISBN :
Author : Edward S. Horton
Publisher : MacMillan Publishing Company
Page : 296 pages
File Size : 11,85 MB
Release : 1988
Category : Health & Fitness
ISBN :
Abstract: Discusses the relationships among nutrition, energy metabolism, and physical exercise, with particular emphasis on normal human physiology, the effects of physical training, and the impact of exercise and nutrition on selected disease states. Each chapter was written by one or more experts in the subject covered. The purpose of this book is to provide the professional with an indepth view of the broad range of nutritional and metabolic implications imposed by exercise.