Electrochemical Sensors in Bioanalysis


Book Description

"Covers the most recent methods and materials for the construction, validation, analysis, and design of electrochemical sensors for bioanalytical, clinical, and pharmaceutical applications--emphasizing the latest classes of enantioselective electrochemical sensors as well as electrochemical sensors for in vivo and in vitro diagnosis, for DNA assay and HIV detection, and as detectors in flow systems. Contains current techniques for the assay or biochemical assay of biological fluids and pharmaceutical compounds."




Electrochemistry of Nucleic Acids and Proteins


Book Description

DNA (sometimes referred to as the molecule of life), is the most interesting and most important of all molecules. Electrochemistry of Nucleic Acids and Proteins: Towards Electrochemical Sensors for Genomics and Proteomics is devoted to the electrochemistry of DNA and RNA and to the development of sensors for detecting DNA damage and DNA hybridization. Volume 1, in the brand new series Perspectives in Bioanalysis, looks at the electroanalytical chemistry of nucleic acids and proteins, development of electrochemical sensors and their application in biomedicine and in the new fields of genomics and proteomics. The authors have expertly formatted the information for a wide variety of readers, including new developments that will inspire students and young scientists to create new tools for science and medicine in the 21st century. * Covers highly sophisticated methods of electrochemical analysis of nucleic acids and proteins * Summarises the present state of electrochemical analysis of nucleic acids and proteins * Includes future trends in the electrochemical analysis in genomics and proteomics




Printed Electrochemical Sensors for Bioanalysis


Book Description

Recently, point-of-care diagnostics has gained great attention because it can improve patient's quality of life. Electrochemical diagnostic systems are promising because of their miniaturizability and low-cost. However, fabrication of such devices requires special skills as well as expensive equipment and supplies. This thesis is based on a research project aimed at fabricating electrochemical sensors combing wax printing and inkjet printing or wax printing and hand painting. The electrochemical sensors can be used for measuring different kinds of electrochemical analytes like dopamine, uric acid by electrochemical methods like amperometry, which can show great calibration curve. The LOD of dopamine, uric acid, ascorbic acid, Nile Blue, hydrogen peroxide and ferrocene is 0.015 μM, 7.3 μM, 30 μM, 1.3 μM, 8 nM and 30 μM, respectively. Further, we can modify the electrochemical sensor by using multiwall carbon nanotube in order to improve the sensitivity of the electrochemical sensors. This modified electrochemical sensor can also be used as immunoassay by sandwich format ELISA for detecting carcinoembryonic antigen (CEA), which has been designated as a reliable biomarker for several types of cancers. We found that the CNT modified hand-painting device can detect CEA down to 0.6 ng/mL, which is three times lower than the cut-off value of diagnosis, i.e. 5 ng/mL in blood.




Electrochemistry for Bioanalysis


Book Description

Electrochemistry for Bioanalysis provides a comprehensive understanding of the benefits and challenges of the application of electrochemical and electroanalytical techniques for measurement in biological samples. The book presents detailed information on measurement in a host of various biological samples from single cells, tissues and in vivo. Sections cover real insights surrounding key experimental design and measurement within multiple complex biological environments. Finally, users will find discussions on emerging topics such as electrogenerated chemiluminescence and the use of additive manufacturing for biosensor fabrication. Continuous learning reinforcement throughout the book, including problems for self-assessment, make this an ideal resource. Balances the fundamentals of electrochemical and neurochemical methods with current advances in the field of bioanalysis Includes self-assessment scenarios on experimental design and validation to teach readers key factors and considerations in measurement Highlights applications (such as sensors and biosensors) and key points within each chapter




Electrochemical Sensors, Biosensors and their Biomedical Applications


Book Description

This book broadly reviews the modem techniques and significant applications of chemical sensors and biosensors. Chapters are written by experts in the field – including Professor Joseph Wang, the most cited scientist in the world and renowned expert on sensor science who is also co-editor. Each chapter provides technical details beyond the level found in typical journal articles, and explores the application of chemical sensors and biosensors to a significant problem in biomedical science, also providing a prospectus for the future.This book compiles the expert knowledge of many specialists in the construction and use of chemical sensors and biosensors including nitric oxide sensors, glucose sensors, DNA sensors, hydrogen sulfide sensors, oxygen sensors, superoxide sensors, immuno sensors, lab on chip, implatable microsensors, et al. Emphasis is laid on practical problems, ranging from chemical application to biomedical monitoring and from in vitro to in vivo, from single cell to animal to human measurement. This provides the unique opportunity of exchanging and combining the expertise of otherwise apparently unrelated disciplines of chemistry, biological engineering, and electronic engineering, medical, physiological. Provides user-oriented guidelines for the proper choice and application of new chemical sensors and biosensors Details new methodological advancements related to and correlated with the measurement of interested species in biomedical samples Contains many case studies to illustrate the range of application and importance of the chemical sensors and biosensors










Electrochemical Sensors Technology


Book Description

This book Electrochemical Sensors Technology mostly reviews the modem methods and significant electrochemical and electroanalytical applications of chemical sensors and biosensors. Chapters of this book are invited and contributed from the experts throughout the world from prominent researchers and scientists in the field of sensors and in the field of electro- and biochemistry. Each chapter provides technical and methodological details beyond the level found in typical journal articles or reviews and explores the application of chemical sensors, environmental sensors, and biosensors to a significant problem in biomedical and environmental science, also providing a prospectus for the future. This book compiles with the expert knowledge of many specialists in the construction and use of chemical sensors and biosensors including chemical sensors, biological sensors, DNA sensors, immunosensors, gaseous sensors, ionic sensors, bioassay sensors, lab-on-chips, devices, portable sensors, microchips, nanosensors, implantable microsensors, and so on in the field of fundamental and applied electrochemistry. Highlights and importance are laid on real or practical problems, ranging from chemical application to biomedical monitoring, from in vitro to in vivo, and from single cell to animal to human measurement. This offers a unique opportunity of exchanging and combining the scientist or researcher in electrochemical sensors in largely chemistry, biological engineering, electronic engineering, and biomedical and physiological fields.




Electrochemical Biosensors


Book Description

Since four decades, rapid detection and monitoring in clinical and food diagnostics and in environmental and biodefense have paved the way for the elaboration of electrochemical biosensors. Thanks to their adaptability, ease of use in relatively complex samples, and their portability, electrochemical biosensors now are one of the mainstays of analy




Electrochemical Sensors


Book Description

Electrochemical Sensors: From Working Electrodes to Functionalization and Miniaturized Devices provides an overview of the materials, preparation and fabrication methods for biosensor applications. The book introduces the field of electrochemistry and its fundamentals, also providing a practical overview of working electrodes as key components for the implementation of sensors and assays. Features covered include the prompt transfer of electrons, favorable redox behavior, biocompatibility, and inertness in terms of electrode fouling. Special attention is dedicated to analyzing the various working materials systems for electrodes used in electrochemical cells such as gold, carbon, copper, platinum and metal oxides. This book is suitable for academics and practitioners working in the disciplines of materials science and engineering, analytical chemistry and biomedical engineering. Introduces key concepts for electrochemistry and biosensors Reviews the most common and emerging materials-based electrodes for sensor applications, including gold, carbon, platinum and metal oxides Discusses both macro and miniaturized electrodes, including their cleaning, engineering, fabrication, examples of working biosensors, and advantages and disadvantages