Yeast Genetics


Book Description

Yeast Genetics: Methods and Protocols is a collection of methods to best study and manipulate Saccharomyces cerevisiae, a truly genetic powerhouse. The simple nature of a single cell eukaryotic organism, the relative ease of manipulating its genome and the ability to interchangeably exist in both haploid and diploid states have always made it an attractive model organism. Genes can be deleted, mutated, engineered and tagged at will. Saccharomyces cerevisiae has played a major role in the elucidation of multiple conserved cellular processes including MAP kinase signaling, splicing, transcription and many others. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Yeast Genetics: Methods and Protocols will provide a balanced blend of classic and more modern genetic methods relevant to a wide range of research areas and should be widely used as a reference in yeast labs.




Benign Anorectal Disorders


Book Description

Management of benign anorectal disorders is challenging for the treating surgeons as the patients are highly distressed, the symptoms are always alarming, and surgical intervention may be associated with lifelong disabilities such as loss of sphincter control. Written by highly experienced colorectal surgeons, this book provides detailed notes on optimal management of these disorders including pre- and post-operative management. Chapters cover the entire range of benign disorders such as hemorrhoids, fissure, fistula-in-ano, anorectal injuries, anal incontinence, rectal prolapse, pelvic floor disorders, benign tumors and ulcers, and strictures. Chapters on surgical anatomy and physiology equip the surgeons with the information necessary to understand the complex anatomy and functioning of this region which makes surgery all the more difficult. Benign Anorectal Disorders is an essential reading for colorectal surgeons, general surgeons, fellows-in-training and the post-graduate students.




Property and The Human Rights Act 1998


Book Description

By giving further effect to the European Convention on Human Rights,the Human Rights Act 1998 has had a significant effect on property law. Article 1 of the First Protocol to the Convention is particularly important, as it protects against the interference with the enjoyment of possessions. Compulsory acquisition, insolvency, planning, taxation, environmental regulation, and landlord and tenant laws are just some of the fields where the British and European courts have already had to assess the impact of the Protocol on private property. The Human Rights Act 1998 also restricts the scope of property rights, as some Convention rights conflict with rights of private property. For example, the Article 8 right to respect for the home has been used to protect against environmental harm, in some cases at the expense of property and economic rights. This book seeks to provide a structured approach to the extensive case law of the European Court of Human Rights and the UK courts on these issues, and to provide guidance on the direction the law is likely to take in future. Chapters cover the history and drafting of the relevant Convention rights, the scope and structure of the rights (especially Article 1 of the First Protocol), and how, through the Human Rights Act 1998, the Convention rights have already affected and are likely to affect developments in selected areas of English law.




Absentee Landowning and Exploitation in West Virginia, 1760-1920


Book Description

Absentee landowning has long been tied to economic distress in Appalachia. In this important revisionist study, Barbara Rasmussen examines the nature of landownership in five counties of West Virginia and its effects upon the counties' economic and social development. Rasmussen untangles a web of outside domination of the region that commenced before the American Revolution, creating a legacy of hardship that continues to plague Appalachia today. The owners and exploiters of the region have included Lord Fairfax, George Washington, and, most recently, the U.S. Forest Service. The overarching concern of these absentee landowners has been to control the land, the politics, the government, and the resources of the fabulously rich Appalachian Mountains. Their early and relentless domination of politics assured a land tax system that still favors absentee landholders and simultaneously impoverishes the state. Class differences, a capitalistic outlook, and an ethic of growth and development pervaded western Virginia from earliest settlement. Residents, however, were quickly outspent by wealthier, more powerful outsiders. Insecurity in landownership, Rasmussen demonstrates, is the most significant difference between early mountain farmers and early American farmers everywhere.




The State of U.S. History


Book Description

Historians are very much aware of the variety of national and international trends that have shaped historical inquiry in recent decades. Americanists, in particular, have been conscious of the growing importance of gender issues, the 'turn' to questions of language and meaning, the increasing significance of cultural matters, and a new emphasis on regional history. The 1990s, moreover, saw a major movement to internationalize approaches to American history by emphasizing comparisons with other countries and cultures. By the end of the twentieth century it was by no means clear whether there was any distinctive 'American' history or, if it did exist, what its main contours were. This book brings together a distinguished international group of scholars in an effort to answer this key question through a sustained interrogation of the periods, themes, fields, problems and perspectives in historical writing on the United States. How have the intricate issues surrounding gender, race, slavery and civil rights been resolved and interpreted in recent American history? How have historians dealt with the complexities of events such as the American Revolution, the Civil War, Reconstruction and the New Deal in developing their historical narratives? In what ways have technological developments in industry, print and film influenced the questions historians ask?The State of U.S. History offers an exciting introduction to the debates surrounding the major trends in American historical debates and the crucial events and influences that have helped define the American experience.




Habeas Corpus


Book Description

We call habeas corpus the Great Writ of Liberty. But it was actually a writ of power. In a work based on an unprecedented study of thousands of cases across more than five hundred years, Paul Halliday provides a sweeping revisionist account of the world's most revered legal device. In the decades around 1600, English judges used ideas about royal power to empower themselves to protect the king's subjects. The key was not the prisoner's "right" to "liberty"Ñthese are modern idiomsÑbut the possible wrongs committed by a jailer or anyone who ordered a prisoner detained. This focus on wrongs gave the writ the force necessary to protect ideas about rights as they developed outside of law. This judicial power carried the writ across the world, from Quebec to Bengal. Paradoxically, the representative impulse, most often expressed through legislative action, did more to undermine the writ than anything else. And the need to control imperial subjects would increasingly constrain judges. The imperial experience is thus crucial for making sense of the broader sweep of the writ's history and of English law. Halliday's work informed the 2008 U.S. Supreme Court ruling in Boumediene v. Bush on prisoners in the Guant‡namo detention camps. His eagerly anticipated book is certain to be acclaimed the definitive history of habeas corpus.




ENGLISH-TIBETAN DICT CONTAININ


Book Description




My Two Moms


Book Description

An advocate and son of same-gender parents recounts his famed address to the Iowa House of Representatives on civil unions, and describes his positive experiences of growing up in an alternative family in spite of prejudice.







General Alexander Lebed


Book Description

Forty-five year old Alexander Lebed is a charismatic figure whose dry wit and brusque no-nonsense style sets him apart from most of the familiar faces of Moscow's political elite. In this brawling autobiography, General Alexander Lebed tells his dramatic life story, demonstrating the strengths that make him a likely candidate for a future Russian leadership role. photos.