Endophytes and Secondary Metabolites


Book Description

This reference work presents an authoritative review of endophytes and their applications to human welfare. Endophytes have become a class of interesting and curious microorganisms due to their intimate intra- and intercellular association with plants for competence, survival and reproduction. They can be bacteria or fungi, and they are usually non-pathogenic to their host. Endophytes have important applications in agriculture and industry, namely, they can help with plant growth, act as biocontrol agents and biosurfactant and secondary metabolite producers, and they are also rich sources of bioactive natural products. Novel and beneficial effects of endophytes are constantly emerging, and this book, divided into four sections, provides readers with the latest developments in this fast expanding field. In the first section, readers will discover the biology of the major groups of endophytes, followed by a summary of conventional and molecular tools for endophytes’ identification in Section II. The production of high-value metabolites by endophytes will be explored in the third section of this book, and in the final section, readers will find several case studies, examples and prospects for endophytes’ application in agriculture and industry. Written by leading international authors, this reference work will appeal to a wide readership, from students and researchers in the field of botany, biotechnology and agriculture to professionals interested in the production and applications of endophytic metabolites.




Endophytes for a Growing World


Book Description

Discusses the role of endophytes in food security, forestry and health. It outlines their general biology, spanning theory to practice.




Fungal Endophytes in Plants


Book Description

This book is a printed edition of the Special Issue "Fungal Endophytes in Plants" that was published in JoF




Endophytic Fungi


Book Description

Endophytic fungi are important biotechnological tools because they produce many secondary metabolites. However, to access this important source of bioactive molecules, it is essential to explore the diversity of endophytic fungi and catalog their species richness in different ecosystems. This book reviews the diversity, characterisation and biocontrol of endophytic fungi.




Endophytes: Biology and Biotechnology


Book Description

This book discusses the latest developments in our understanding of microbial endophytes, their ecology, diversity and potential biotechnological applications. It covers all the latest advances concerning the endophytic interaction of microorganisms in a wide array of plants, reported on by experts from the entire globe. The diverse microbial community, which consists of archaeal, bacterial, fungal and protistic taxa, can be found in all plants. The endophytic lifecycle reveals how microorganisms play essential roles in plant growth, fitness and diversification. Diversity is an integral component of ecology. In soil ecology, below-ground interactions of plant and microorganisms are accomplished by endophytes, which reside in the plant’s internal tissues. The microbial world in general and endophytes in particular reflect a unique degree of genetic and functional (metabolic) diversity. Currently, significant attention is being paid to endophytic microorganisms, as their repertoire of cells and metabolites hold immense potential with regard to biotechnological applications for sustainable development. The diversity of bacterial endophytes guarantees that there are endophytes capable of forming compatible associations with all agronomically important plants, including monocots and dicots. The study of endophytes’ diverse nature in connection with biodiesel, medicinal and agriculturally important crop can lead to a better understanding of applicable facets. The topics in this dynamic field of study are so diverse and vast. This volume will benefit all botanists, microbiologists, ecologists, plant pathologists, physiologists, agronomists, molecular biologists, environmentalists, policymakers, conservationists and NGOs working to protect species and prevent the loss of biologically significant genetic material.




Advances in Endophytic Research


Book Description

​In recent years there has been significant attention paid on the endophytic research by various groups working within this domain. Mutualistic endophytic microbes with an emphasis on the relatively understudied fungal endophytes are the focus of this special book. Plants are associated with micro-organisms: endophytic bacteria and fungi, which live inter- and intra-cellularly without inducing pathogenic symptoms, but have active biochemical and genetic interactions with their host. Endophytes play vital roles as plant growth promoters, biocontrol agents, biosurfactant producers, enzymes and secondary metabolite producers, as well as providing a new hidden repertoire of bioactive natural products with uses in pharmaceutical, agrochemical and other biotechnological applications. The increasing interest in endophytic research generates significant progress in our understanding of the host-endophyte relationship at molecular and genetic level. The bio-prospection of microbial endophytes has led to exciting possibilities for their biotechnological application as biocontrol agent, bioactive metabolites, and other useful traits. Apart from these virtues, the microbial endophytes may be adapted to the complex metabolism of many desired molecules that can be of significant industrial applications. These microbes can be a useful alternative for sustainable solutions for ecological control of pests and diseases, and can reduce the burden of excess of chemical fertilizers for this purpose. This book is an attempt to review the recent development in the understanding of microbial endophytes and their potential biotechnological applications. This is a collection of literature authored by noted researchers having signatory status in endophytic research and summarizes the development achieved so far, and future prospects for further research in this fascinating area of research.




Biocontrol Agents and Secondary Metabolites


Book Description

Biocontrol and Secondary Metabolites: Applications and Immunization for Plant Growth and Protection covers established and updated research on emerging trends in plant defense signaling in, and during, stress phases. Other topics cover growth at interface as a sustainable way of life and the context of human welfare and conservation of fungi as a group of organisms. Further, the book explores induced systemic resistance using biocontrol agents and/or secondary metabolites as a milestone for sustainable agricultural production, thus providing opportunities for the minimization or elimination of the use of fungicides. - Presents an overview on mechanisms by which plants protect themselves against herbivory and pathogenic microbes - Identifies the use of immunization as a popular and effective alternative to chemical pesticides - Explores how these fungi help crop plants in better uptake of soil nutrients, increase soil fertility, produce growth promoting substances, and secrete metabolites that act as bio-pesticides




Advances in Endophytic Fungal Research


Book Description

Plant endophytes are a potential source for the production of bioactive compounds that can fight against devastating diseases in both plants and humans. Among these endophytic microorganisms, endophytic fungi are one of the dominant group of microorganisms with a potential role in plant growth promotion and the discovery of noble bioactive natural products. Endophytic fungi possess several bioactivities like anticancer, antimicrobial, insecticidal, plant growth stimulants, crop protection, phytoremediation, etc. Presence of modular biosynthetic genes clusters like PKS and NRPS in several endophytic fungi underscores the need to understand and explore such organisms. This volume presents and demonstrates the applied aspects of endophytic fungi. Practical applications of such endophytes are discussed in detail, including studies in pharmaceutical development and agricultural management of important microbial diseases. The beneficial effects that endophytic fungi provide to host plants—enhancing growth, increasing fitness, strengthening tolerance to abiotic and biotic stresses through secondary metabolites—are also discussed. The reader is provided with a comprehensive and detailed understanding of such relationships between endophytic fungi and their host.




Microbial Endophytes


Book Description

Examining intercellular infections in certain plant species that lead to a symbiotic relationship between the host and its endophytic microbes, this volume demonstrates the ability of many types of endosymbionts, acting as a unit with hosts to better survive, compete and reproduce. Practical applications of such endophytes are also discussed, for e




Biotechnological Approaches to Enhance Plant Secondary Metabolites


Book Description

Thousands of secondary metabolites are produced by plants to withstand unfavourable environmental conditions and are important molecules for nutraceutical, agro, cosmetic and pharmaceutical industries, etc. Harvesting of plants for the extraction of these important metabolites can threaten the plant germplasm, and various medicinally important plants are at the verge of extinction. Based on need, various methods and strategies were developed and followed by researchers from time to time to save the plant germplasm and produce important secondary metabolites efficiently to meet their growing demands. Biotechnological Approaches to Enhance Plant Secondary Metabolites: Recent Trends and Future Prospects provides a comprehensive introduction and review of state-of-the-art biotechnological tools in this field of research at global level. The methodologies are highlighted by real data examples in both in vitro and in vivo level studies. The book: • Highlights and provides overviews of the synthesis, classification, biological function and medicinal applications of the recent advancements for the enhanced production of novel secondary metabolites in plants • Provides an overview of the role of induced mutation, salinity stress and brassinosteroids impact to increase the secondary metabolic contents in plants and suggests an increase in enzymatic activity in plants could be due to various point mutations, which in turn could play a role at transcriptome levels • Discusses the significant role of endophytes to enhance the contents of plant secondary metabolites • Alternatively, suggests the urgent need to set up the standard operating procedures using hydroponics system of cultivation for significant enhancement of secondary metabolite contents • Enlists various in vitro techniques to enhance plant secondary metabolites contents using plant tissue culture approaches • Provides a systematic overview of state-of-the-art biotechnological tools CRISPER Cas9 and RNAi to enhance the plant secondary metabolite contents • Recommends CRISPER Cas9 technology over RNAi, ZFNs and TALENs because of its relatively simple and high precision method with an easily programmable tool This serves as a reference book for the researchers working in the field of plant secondary metabolites and pharmaceutical industries at global level.