Symbiogenesis


Book Description

Evolution.




Acquiring Genomes


Book Description

In this groundbreaking book, Lynn Margulis and Dorion Sagan present an answer to one of the enduring mysteries of evolution -- the source of inherited variation that gives rise to new species. Random genetic mutation, long believed to be the main source of variation, is only a marginal factor. As the authors demonstrate in this book, the more important source of speciation, by far, is the acquisition of new genomes by symbiotic merger. The result of thirty years of delving into a vast, mostly arcane literature, this is the first book to go beyond -- and reveal the severe limitations of -- the "Modern Synthesis" that has dominated evolutionary biology for almost three generations. Lynn Margulis, whom E. O. Wilson called "one of the most successful synthetic thinkers in modern biology," and her co-author Dorion Sagan have written a comprehensive and scientifically supported presentation of a theory that directly challenges the assumptions we hold about the variety of the living world.




Case Studies in Cell Biology


Book Description

Case Studies in Cell Biology presents real world scenarios to help readers use science process and reasoning skills. The case studies require application and analyzation of concepts beyond rote memory of biological concepts. The book is based on the student learning outcomes from the American Society for Cell Biology, offering practical application for both the classroom and research laboratory. - Guides the reader in applying knowledge directly to real world scenarios - Includes case studies to bridge foundational cell biological concepts to translational science - Aids students in synthesizing information and applying science processes




Mitochondria and Anaerobic Energy Metabolism in Eukaryotes


Book Description

Mitochondria are sometimes called the powerhouses of eukaryotic cells, because mitochondria are the site of ATP synthesis in the cell. ATP is the universal energy currency, it provides the power that runs all other life processes. Humans need oxygen to survive because of ATP synthesis in mitochondria. The sugars from our diet are converted to carbon dioxide in mitochondria in a process that requires oxygen. Just like a fire needs oxygen to burn, our mitochondria need oxygen to make ATP. From textbooks and popular literature one can easily get the impression that all mitochondria require oxygen. But that is not the case. There are many groups of organismsm known that make ATP in mitochondria without the help of oxygen. They have preserved biochemical relicts from the early evolution of eukaryotic cells, which took place during times in Earth history when there was hardly any oxygen avaiable, certainly not enough to breathe. How the anaerobic forms of mitochondria work, in which organisms they occur, and how the eukaryotic anaerobes that possess them fit into the larger picture of rising atmospheric oxygen during Earth history are the topic of this book.




Phylogenomics


Book Description

This unique textbook provides a clear and concise overview of the key principles of the complex field of phylogenomics, with a particular focus on sequencing technologies that are crucial to studying and understanding interrelations in evolutionary genomics. It includes chapters dedicated to the analysis of nucleotide sequences using assembling and alignment methods and also discusses the main strategies for phylogenetic studies, systematic errors and their correction. This highly readable textbook is intended for graduate students and young researchers with an interest in phylogenetics and evolutionary developmental biology.




Mitochondrial Function and Biogenesis


Book Description

Mitochondria are complex organelles, possessing a double-membrane and even their own genome, the mtDNA. They play a pivotal role in cellular metabolism, respiration, and production of ATP essential for the normal function of all human organ systems. It is not surprising, therefore, that genetic defects of mitochondrial functions cause a wide spectrum of human diseases. This book provides the first modern and truly comprehensive coverage of the biochemistry, genetics, and pathology of mitochondria in different organisms. It particularly focuses on the recent advances in our understanding of basic mitochondrial research to the consequences of dysfunction at the molecular level. The 13 contributions written by leading researchers in the field include topics such as: mitochondrial genome evolution and mtDNA stability, mitochondrial biogenesis and protein quality control, mitochondrial morphology, assembly and function of the mitochondrial energy generation apparatus and mitochondrial metabolic pathways. These are particularly oriented to link in these various mitochondrial pathways to the clinical consequences of their dysfunctions.




Evolution by Association


Book Description

In this comprehensive history of symbiosis theory--the first to be written--Jan Sapp masterfully traces its development from modest beginnings in the late nineteenth century to its current status as one of the key conceptual frameworks for the life sciences. The symbiotic perspective on evolution, which argues that "higher species" have evolved from a merger of two or more different kinds of organisms living together, is now clearly established with definitive molecular evidence demonstrating that mitochondria and chloroplasts have evolved from symbiotic bacteria. In telling the exciting story of an evolutionary biology tradition that has effectively challenged many key tenets of classical neo-Darwinism, Sapp sheds light on the phenomena, movements, doctrines, and controversies that have shaped attitudes about the scope and significance of symbiosis. Engaging and insightful, Evolution by Association will be avidly read by students and researchers across the life sciences.




The Origin of Eukaryotic Cells


Book Description




Endosymbiotic Organelle Acquisition


Book Description

Zusammenfassung: This volume provides in depth reviews of the protein targeting translocation processes, gene transfer processes and genome reduction processes in the host and in the endosymbiont which were likely utilized during the evolution of an endosymbiont into mitochondria, mitochondria related organelles, simple and complex chloroplasts. These reviews cover both the current understanding of the host processes as well as the evolutionary outcomes used by these organelles for protein targeting and translocation. Reviews of the current knowledge of these topics are plentiful but scattered throughout the bacterial, parasite, plant and animal literature; here, reviews of current knowledge with evolutionary outcomes and future perspectives, written by leading researchers in their respective areas, are united into one comprehensive volume, essential for students and scientists interested in or working on subcellular protein localization, protein targeting signals, translocation of proteins across and insertion into membranes, nucleic acid transfer between genomes, genome reduction and evolution of mitochondria and chloroplast.




Eukaryotic Microbes


Book Description

Eukaryotic Microbes presents chapters hand-selected by the editor of the Encyclopedia of Microbiology, updated whenever possible by their original authors to include key developments made since their initial publication. The book provides an overview of the main groups of eukaryotic microbes and presents classic and cutting-edge research on content relating to fungi and protists, including chapters on yeasts, algal blooms, lichens, and intestinal protozoa. This concise and affordable book is an essential reference for students and researchers in microbiology, mycology, immunology, environmental sciences, and biotechnology. Written by recognized authorities in the field Includes all major groups of eukaryotic microbes, including protists, fungi, and microalgae Covers material pertinent to a wide range of students, researchers, and technicians in the field