EPA's Neurotoxicity Risk Assessment Guidelines
Author : Society of Toxicology
Publisher :
Page : pages
File Size : 16,80 MB
Release : 1997
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Author : Society of Toxicology
Publisher :
Page : pages
File Size : 16,80 MB
Release : 1997
Category :
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Author :
Publisher :
Page : 92 pages
File Size : 41,73 MB
Release : 1998
Category : Neurotoxicology
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Author :
Publisher :
Page : 94 pages
File Size : 11,71 MB
Release : 1998
Category : Health risk assessment
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Author :
Publisher :
Page : 34 pages
File Size : 24,38 MB
Release : 1997
Category : Neurotoxicology
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Author : Eastern Research Group, Inc
Publisher :
Page : 172 pages
File Size : 27,59 MB
Release : 1992
Category : Neurotoxicology
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Author :
Publisher :
Page : 86 pages
File Size : 48,84 MB
Release : 1994
Category : Medical
ISBN :
Author : National Research Council
Publisher : National Academies Press
Page : 167 pages
File Size : 24,23 MB
Release : 1992-02-01
Category : Science
ISBN : 0309045312
Scientists agree that exposure to toxic agents in the environment can cause neurological and psychiatric illnesses ranging from headaches and depression to syndromes resembling parkinsonism. It can even result in death at high exposure levels. The emergence of subclinical neurotoxicity-the concept that long-term impairments can escape clinical detection-makes the need for risk assessment even more critical. This volume paves the way toward definitive solutions, presenting the current consensus on risk assessment and environmental toxicants and offering specific recommendations. The book covers: The biologic basis of neurotoxicity. Progress in the application of biologic markers. Reviews of a wide range of in vitro and in vivo testing techniques. The use of surveillance and epidemiology to identify neurotoxic hazards that escape premarket screening. Research needs. This volume will be an important resource for policymakers, health specialists, researchers, and students.
Author : National Research Council
Publisher : National Academies Press
Page : 204 pages
File Size : 24,85 MB
Release : 2011-05-31
Category : Science
ISBN : 0309211964
Formaldehyde is ubiquitous in indoor and outdoor air, and everyone is exposed to formaldehyde at some concentration daily. Formaldehyde is used to produce a wide array of products, particularly building materials; it is emitted from many sources, including power plants, cars, gas and wood stoves, and cigarettes; it is a natural product in come foods; and it is naturally present in the human body as a metabolic intermediate. Much research has been conducted on the health effects of exposure to formaldehyde, including effects on the upper airway, where formaldehyde is deposited when inhaled, and effects on tissues distant from the site of initial contact. The U.S. Environmental Protection Agency (EPA) released noncancer and cancer assessments of formaldehyde for its Intergated Risk Information System (IRIS) in 1990 and 1991, respectively. The agency began reassessing formaldehyde in 1998 and released a draft IRIS assessment in June 2010. Given the complexity of the issues and the knowledge that the assessment will be used as the basis of regulatory decisions, EPA asked the National Research Council (NRC) to conduct an independent scientific review of the draft IRIS assessment. In this report, the Committee to Review EPA's Draft IRIS Assessment of Formaldehyde first addresses some general issues associated with the draft IRIS assessment. The committee next focuses on questions concerning specific aspects of the draft assessment, including derivation of the reference concentrations and the cancer unit risk estimates for formaldehyde. The committee closes with recommendations for improving the IRIS assessment of formaldehyde and provides some general comments on the IRIS development process.
Author :
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Page : pages
File Size : 40,30 MB
Release : 1998
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Author : United States. Environmental Protection Agency. Office of Health and Environmental Assessment
Publisher :
Page : 302 pages
File Size : 13,76 MB
Release : 1988
Category : Carcinogenicity testing
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