Essentials of Restenosis


Book Description

Leading interventional cardiologists, including Patrick Serruys, provide the gold-standard reference on the treatment of restenosis for interventional cardiologists. Dr. Serruys, who pioneered the use of drug-eluting stents, and other pioneers in the field, cover everything from non-invasive imaging, to eluting stents, to brachytherapy through to the latest molecular biology-based treatments including antisense, stem cells and gene therapy.




Mechanisms of Vascular Disease


Book Description

This extensively revised third edition provides a practically applicable guide to the pathophysiology, assessment and management of vascular disorders encountered in vascular surgical practice. It features detailed information on the latest developments in the pathophysiology of conditions including atherosclerosis, multi-organ failure, limb compartment syndromes and Raynaud’s phenomenon in a clear easy to digest format. Disorders such as reperfusion injuries, vasculitides, and aortic dissection are covered. Furthermore, key topics in vascular and endovascular practice such as radiation biology and radiation safety are also detailed. Each chapter contains a set of learning objectives and key references, enabling the reader to quickly identify key points. Mechanisms of Vascular Disease: A Textbook for Vascular Specialists comprehensively covers a variety of common and unusual pathophysiologies encountered in vascular surgery, and is an ideal resource for both the trainee, and practicing clinical vascular surgeon seeking an up-to-date resource on the topic.




Textbook of Catheter-Based Cardiovascular Interventions


Book Description

This book is a fully updated and revised second edition of a highly successful text in which a new concept of knowledge mining, based on explication and transfer of interventional knowledge of experts, has been implemented. The dedicated training program that is set out will serve the needs of all interventional operators, whether cardiologists, vascular surgeons, vascular specialists, or radiologists, enabling them to achieve a consistent expert level across the entire broad spectrum of catheter-based interventions. Operator skills – and in particular decision-making and strategic skills – are the most critical factors for the outcome of catheter-based cardiovascular interventions. Currently, such skills are commonly developed by the empirical trial and error method only. The explicit teaching, training, and learning approach adopted in this book permits the rapid transfer of interventional knowledge and enables individual operators to negotiate steep learning curves and acquire complex skills in a highly efficient manner. It will thereby offer invaluable assistance in meeting successfully the challenges of modern cardiovascular care.




Mechanisms of Vascular Disease


Book Description

New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.




Practical Manual of Interventional Cardiology


Book Description

This practical handbook is based on an internal working manual developed by staff and fellows at Mount Sinai Heart Cardiovascular Catheterization Laboratory, renowned for its high-volume and low complication complex coronary procedures. The Practical Handbook of Interventional Cardiology captures the knowledge and methodological know-how from leaders in interventional cardiology, it intends to guide users in a stepwise, methodical and practical approach through various cardiac interventional procedures in order to achieve maximum patient safety and improved outcomes. From patient selection, preoperative work-up, setting up equipment to step-by-step illustrations of various procedural details and troubleshooting, this handbook captures all the details necessary to perform the simplest to the most complex cardiac interventions. The book is designed for cardiologists and trainees who desire an efficient way to review the steps of various cardiac interventional procedures and a quick, reliable reference for everyday use.




Vascular Brachytherapy


Book Description

With the first coronary balloon angioplasty in 1977 came the challenge of the wound healing process of retenosis. Together these events spawned a new field of medicine, vascular brachytherapy, conceived to resolve this leading complication of vascular intervention. In the ensuing 20 year quest to cure restenosis, radiation vascular therapy appears to be the next logical step, but it still needs validation. Just two years after the first edition, this second edition of Vascular Brachytherapy fulfils the promise to provide updated information about the meteoric progress made from recent collaborative investigations within this field. Migrating from ideas and pre-clinical observation to clinical practice, this second edition contains 48 new or revised chapters contributed by well known medical experts from widely disparate fields of medicine. Scientists, cardiologists, radiation safety officers, regulators, engineers and technicians substantiate their observations with clinical and non-clinical data, basic radiation principles and issues from an economic, regulatory and safety perspective. Very little is known about the immediate patient risks, environmental concerns and long term pathobiological responses. For a field which is still in its honeymoon phase due to early technology success, this single volume will serve as a long-range educational tool and trace, giving the field of vascular brachytherapy the intense and continuous evaluation it deserves. For an audience of clinicians, scientists and researchers from all the represented medical disciplines, this book provides in depth information and exposure to subjects within these diverse areas of expertise.




Cost-Effectiveness in Health and Medicine


Book Description

A unique, in-depth discussion of the uses and conduct of cost-effectiveness analyses (CEAs) as decision-making aids in the health and medical fields, this volume is the product of over two years of comprehensive research and deliberation by a multi-disciplinary panel of economists, ethicists, psychometricians, and clinicians. Exploring cost-effectiveness in the context of societal decision-making for resource allocation purposes, this volume proposes that analysts include a "reference-case" analysis in all CEAs designed to inform resource allocation and puts forth the most explicit set of guidelines (together with their rationale) ever defined on the conduct of CEAs. Important theoretical and practical issues encountered in measuring costs and effectiveness, evaluating outcomes, discounting, and dealing with uncertainty are examined in separate chapters. Additional chapters on framing and reporting of CEAs elucidate the purpose of the analysis and the effective communication of its findings. Cost-Effectiveness in Health and Medicine differs from the available literature in several key aspects. Most importantly, it represents a consensus on standard methods--a feature integral to a CEA, whose principal goal is to permit comparisons of the costs and health outcomes of alternative ways of improving health. The detailed level at which the discussion is offered is another major distinction of this book, since guidelines in journal literature and in CEA-related books tend to be rather general--to the extent that the analyst is left with little guidance on specific matters. The focused overview of the theoretical background underlying areas of controversy and of methodological alternatives, and, finally, the accessible writing style make this volume a top choice on the reading lists of analysts in medicine and public health who wish to improve practice and comparability of CEAs. The book will also appeal to decision-makers in government, managed care, and industry who wish to consider the uses and limitations of CEAs.




Drug-Coated Balloons


Book Description

This book provides a comprehensive, up-to-date summary of drug-coated balloon (DCB) technology and the role of DCBs in the treatment of coronary and peripheral arterial disease. In addition to clear explanation of how DCBs works, readers will find an enlightening analysis of the mistakes and successes of the past decade and the emergence of the latest delivery systems, which combine a more deliverable device with much improved drug delivery to the vessel wall. The full range of current applications of DCBs are reviewed in detail, drawing on the latest scientific evidence. Due attention is paid to newer devices, with provision of technical insights and documentation of the available clinical data. Ongoing research projects, remaining technical challenges, likely future directions, and reimbursement issues are also carefully considered. This book will be a useful tool for any interventional cardiologist, interventional radiologist, or vascular surgeon who wishes to acquire a deep knowledge of this technology and its application in both coronary and peripheral interventions.




Bioresorbable Scaffolds


Book Description

This book focuses on the coronary bioresorbable scaffold, a new interventional treatment for coronary artery disease, differentiated from a permanent metallic stent. The book provides an overview of the technology including non-clinical studies and clinical evidences in order to help clinicians understand the appropriate application of the technology and the optimal techniques of implantation. It covers the basics of bioresorbable scaffolds; bench test results; preclinical studies; clinical evidences; and tips and tricks of implantation.




Essential Interventional Cardiology E-Book


Book Description

This title is directed primarily towards health care professionals outside of the United States. This book has been prepared by professionals working in the UK. It covers the basic principles and practice of interventional cardiology, vascular and non-vascular, written specifically for the general cardiologist. Designed to facilitate easy access to key information, it contains numerous line illustrations, diagrams, graphs, and charts. The entire spectrum of interventional cardiology is covered in an easy-to-read format. In this new edition are fifteen new chapters written by experts from around the world. The excellent appendix of trials in interventional cardiology has been fully updated making this the best available source on how to apply trials to clinical practice. Includes editors and contributors from the US and Europe for a truly international perspective. Begins each chapter with 6-10 key points written in bullet format that summarize important concepts in the chapter, making reference a snap. Includes extensive coverage of new technologies for interventional cardiology, including lasers, cutting balloons, and distal protection to keep you completely current. Covers high problem areas for intervention, including new material on chronic total occlusions, bifurcation lesions and PCI in small vessels. Adds a new section on peripheral vascular intervention including the new development areas for interventional cardiologists like carotid, renal and lower extremity. Contains new information on hot topics such as ASD, PFO closure, and aortic valve intervention.