Computational Systems Biology


Book Description

This volume introduces the reader to the latest experimental and bioinformatics methods for DNA sequencing, RNA sequencing, cell-free tumour DNA sequencing, single cell sequencing, single-cell proteomics and metabolomics. Chapters detail advanced analysis methods, such as Genome-Wide Association Studies (GWAS), machine learning, reconstruction and analysis of gene regulatory networks and differential coexpression network analysis, and gave a practical guide for how to choose and use the right algorithm or software to handle specific high throughput data or multi-omics data. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Computational Systems Biology: Methods and Protocols aims to ensure successful results in the further study of this vital field.




The Palgrave Handbook of Leadership in Transforming Asia


Book Description

This handbook provides a comprehensive overview and evaluation of the variety of organizational leadership issues within the Asian region. It highlights the relationship between leaders and their followers, and the complexity of leadership research and practices in Asian transformational economies. Covering a wide range of contexts and perspectives, the chapters are based on empirical studies with evidence-based findings that can be used as case studies for academics and practitioners. The handbook makes significant contributions to leadership theory including practice and assists international researchers, practitioners and students in understanding the influence of the Asian culture and its impact on leadership.




Surviving Death


Book Description

THE INSPIRATION FOR THE NETFLIX ORIGINAL SERIES • An impeccably researched, page-turning investigation, revealing stunning and wide-ranging evidence suggesting that consciousness survives death, from New York Times bestselling author Leslie Kean “An engaging, personal, and transformative journey that challenges the skeptic and informs us all.”—Harold E. Puthoff, Ph.D., director of the Institute for Advanced Studies at Austin In this groundbreaking book, award-winning journalist and New York Times bestselling author Leslie Kean investigates the unexplained continuity of the human psyche after death. Here, Kean explores the most compelling case studies of young children reporting verifiable details from past lives, contemporary mediums who seem to defy the boundaries of the brain and of the physical world, apparitions providing information about their lives on earth, and people who die and then come back to report journeys into another dimension. Based on facts and scientific studies, Surviving Death includes fascinating chapters by medical doctors, psychiatrists, and PhDs from four countries. As a seasoned reporter whose work transcends belief systems and ideology, Kean enriches the narrative by including her own unexpected, confounding experiences encountered while she probed the question concerning all of us: Do we survive death?




Art as We Don't Know it


Book Description

What worlds are revealed when we listen to alpacas, make photographs with yeast or use biosignals to generate autonomous virtual organisms? Bioart invites us to explore artistic practices at the intersection of art, science and society. This rapidly evolving field utilises the tools of life sciences to examine the materiality of life; the collision of human and nonhuman. Microbiology, virtual reality and robotics cross disciplinary boundaries to engage with arts as artists and scientists work together to challenge the ways in which we understand and observe the world. This book offers a stimulating and provocative exploration into worlds emerging, seen through art as we don?t know it ? yet.00'Art as We Don?t Know It' showcases art and research that has grown and flourished within the wider network of both the Bioart Society and Biofilia during the previous decade. The book features a foreword by curator and art historian Mónica Bello, and a selection of peer-reviewed articles, personal accounts and interviews, artistic contributions and collaborative projects which illustrate the breadth and diversity of bioart. The resulting book is a tantalising and invaluable indicator of trends, visions and impulses in the field.




Architecture and the Smart City


Book Description

Increasingly the world around us is becoming ‘smart.’ From smart meters to smart production, from smart surfaces to smart grids, from smart phones to smart citizens. ‘Smart’ has become the catch-all term to indicate the advent of a charged technological shift that has been propelled by the promise of safer, more convenient and more efficient forms of living. Most architects, designers, planners and politicians seem to agree that the smart transition of cities and buildings is in full swing and inevitable. However, beyond comfort, safety and efficiency, how can ‘smart design and technologies’ assist to address current and future challenges of architecture and urbanism? Architecture and the Smart City provides an architectural perspective on the emergence of the smart city and offers a wide collection of resources for developing a better understanding of how smart architecture, smart cities and smart systems in the built environment are discussed, designed and materialized. It brings together a range of international thinkers and practitioners to discuss smart systems through four thematic sections: ‘Histories and Futures’, ‘Agency and Control’, ‘Materialities and Spaces’ and ‘Networks and Nodes’. Combined, these four thematic sections provide different perspectives into some of the most pressing issues with smart systems in the built environment. The book tackles questions related to the future of architecture and urbanism, lessons learned from global case studies and challenges related to interdisciplinary research, and critically examines what the future of buildings and cities will look like.




Wittgenstein and Merleau-Ponty


Book Description

Maurice Merleau-Ponty and Ludwig Wittgenstein are two of the most important philosophers of the twentieth century, yet their work is generally regarded as standing in contrast to one another. However, as this outstanding collection demonstrates they both reject a Cartesian picture of the mind and sought to offer an alternative that does justice to the role played by bodily action, language, and our membership within a community that shares a way of life. This is the first collection to compare and contrast the work of these two major philosophers. Fundamental topics and problems discussed include the role of community in their philosophies; Merleau-Ponty on description and depiction and Wittgenstein on saying and doing; the role of language; their treatment of expression; their relation to the philosophy of the Vienna Circle; solipsism; and rule-following. It is essential reading for anyone studying the work of Wittgenstein and Merleau-Ponty, as well as those interested in phenomenology, philosophy of mind, and philosophy of language.




Knowledge and Reality


Book Description

This book brings together a selection of Colin McGinn's philosophical essays from the 1970s to the 1990s, whose unifying theme is the relation between the mind and the world. The essays range over a set of prominent topics in contemporary philosophy, including the analysis of knowledge, the a priori, necessity, possible worlds, realism, mental representation, appearance and reality, and color.




Education Policy and Practice


Book Description

Education Policy and Practice provides teachers with effective strategies for meeting racial, linguistic, and cultural diversity within the classroom, creating a framework teachers can use to improve urban school outcomes and in-class interaction.